Exploding the Gene Myth


Book Description

"Is human behavior genetic? Do we inherit our intelligence, our sexuality, our predispositions to illness or depression, or our particular talents through our genes? Newspaper headlines today tout genetic explanations of everything from cancer to alcoholism and criminality. But as Exploding the Gene Myth demonstrates, such explanations are nearly always exaggerated or unfounded, ignoring the complex interactions of genes with environment at every level. Like the eugenic theories of seventy-five years ago, the new genetic determinism serves a conservative social agenda, reflecting our society's eagerness to blame ill health and misfortune on individuals rather than on social and environmental conditions." "Exploding the Gene Myth explains in clear, accessible language how genes really work. Ruth Hubbard and Elijah Wald then evaluate the tremendous impact of genetic information on how we are treated by doctors and health insurance companies, by schools, by the criminal justice system, and by potential employers." "The authors are especially critical of the multi-billion-dollar Human Genome Initiative, the huge research project to map every gene on the DNA of a prototypical human being. Hubbard and Wald deflate the grandiose promises of therapeutic benefits that are supposed to emerge from the project. They point instead to the real threats to privacy and civil liberties already resulting from the unregulated increase in genetic predictions." "At a time when the biosciences are undergoing a revolution, the enthusiasm of scientists and the media about new genetic information and technologies needs to be tempered with realism. Hubbard and Wald argue that all citizens, not just scientists, should be able to participate in making the necessary decisions about how to regulate information, protect privacy, and avoid discrimination. Exploding the Gene Myth is a forceful plea for a society that would invest in safe, healthful living and working conditions for everyone rather than the search for ideal or improved genes."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved




Exploding the Gene Myth


Book Description

How Genetic Information Is Produced and Manipulated by Scientists, Physicians, Employers, Insurance Companies, Educators, and Law Enforcers




Genetics and the Manipulation of Life


Book Description

A provocative work that challenges our common assumptions about nature and science, this book is for all who want to understand the biological revolution of the late twentieth century. In this clearly written, well-illustrated book, Holdrege describes, using fascinating examples, how living organisms develop and exist within the context of their environments. In an age when we are able to reshape life on earth, this book offers a deeper, more complex vision of nature, one that can help us establish a more conscious and responsible connection to the world around us.




Genetic Explanations


Book Description

Can genes determine which fifty-year-old will succumb to Alzheimer’s, which citizen will turn out on voting day, and which child will be marked for a life of crime? Yes, according to the Internet, a few scientific studies, and some in the biotechnology industry who should know better. Sheldon Krimsky and Jeremy Gruber gather a team of genetic experts to argue that treating genes as the holy grail of our physical being is a patently unscientific endeavor. Genetic Explanations urges us to replace our faith in genetic determinism with scientific knowledge about how DNA actually contributes to human development. The concept of the gene has been steadily revised since Watson and Crick discovered the structure of the DNA molecule in 1953. No longer viewed by scientists as the cell’s fixed set of master molecules, genes and DNA are seen as a dynamic script that is ad-libbed at each stage of development. Rather than an autonomous predictor of disease, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning. Emphasizing relatively new understandings of genetic plasticity and epigenetic inheritance, the authors put into a broad developmental context the role genes are known to play in disease, behavior, evolution, and cognition. Rather than dismissing genetic reductionism out of hand, Krimsky and Gruber ask why it persists despite opposing scientific evidence, how it influences attitudes about human behavior, and how it figures in the politics of research funding.




Reclaiming Our Health


Book Description

The author calls for a revolution in health care, criticizing its hostility to alternative medicine and its bias against women.




The Missing Gene


Book Description

Researchers still haven't found the genes that underlie schizophrenia, bipolar disorder, ADHD, and autism; perhaps they do not exist. A genetic researcher in psychiatry and psychology urges we return our focus to family, social, and political environments as the sources of psychological distress.




The Trouble with Nature


Book Description

Roger N. Lancaster provides the definitive rebuttal of evolutionary just-so stories about men, women, and the nature of desire in this spirited exposé of the heterosexual fables that pervade popular culture, from prime-time sitcoms to scientific theories about the so-called gay gene. Lancaster links the recent resurgence of biological explanations for gender norms, sexual desires, and human nature in general with the current pitched battles over sexual politics. Ideas about a "hardwired" and immutable human nature are circulating at a pivotal moment in human history, he argues, one in which dramatic changes in gender roles and an unprecedented normalization of lesbian and gay relationships are challenging received notions and commonly held convictions on every front. The Trouble with Nature takes on major media sources—the New York Times, Newsweek—and widely ballyhooed scientific studies and ideas to show how journalists, scientists, and others invoke the rhetoric of science to support political positions in the absence of any real evidence. Lancaster also provides a novel and dramatic analysis of the social, historical, and political backdrop for changing discourses on "nature," including an incisive critique of the failures of queer theory to understand the social conflicts of the moment. By showing how reductivist explanations for sexual orientation lean on essentialist ideas about gender, Lancaster invites us to think more deeply and creatively about human acts and social relations.




Genetic Engineering


Book Description

Discusses current and potential uses of genetic engineering in fields such as medicine, criminal investigation, and agriculture and examines some of the ethical questions involved.




Genes in Development


Book Description

In light of scientific advances such as genomics, predictive diagnostics, genetically engineered agriculture, nuclear transfer cloning, and the manipulation of stem cells, the idea that genes carry predetermined molecular programs or blueprints is pervasive. Yet new scientific discoveries—such as rna transcripts of single genes that can lead to the production of different compounds from the same pieces of dna—challenge the concept of the gene alone as the dominant factor in biological development. Increasingly aware of the tension between certain empirical results and interpretations of those results based on the orthodox view of genetic determinism, a growing number of scientists urge a rethinking of what a gene is and how it works. In this collection, a group of internationally renowned scientists present some prominent alternative approaches to understanding the role of dna in the construction and function of biological organisms. Contributors discuss alternatives to the programmatic view of dna, including the developmental systems approach, methodical culturalism, the molecular process concept of the gene, the hermeneutic theory of description, and process structuralist biology. None of the approaches cast doubt on the notion that dna is tremendously important to biological life on earth; rather, contributors examine different ideas of how dna should be represented, evaluated, and explained. Just as ideas about genetic codes have reached far beyond the realm of science, the reconceptualizations of genetic theory in this volume have broad implications for ethics, philosophy, and the social sciences. Contributors. Thomas Bürglin, Brian C. Goodwin, James Griesemer, Paul Griffiths, Jesper Hoffmeyer, Evelyn Fox Keller, Gerd B. Müller, Eva M. Neumann-Held, Stuart A. Newman, Susan Oyama, Christoph Rehmann-Sutter, Sahotra Sarkar, Jackie Leach Scully, Gerry Webster, Ulrich Wolf




Our Genes, Our Choices


Book Description

Our Genes, Our Choices: How Genotype and Gene Interactions Affect Behavior, Second Edition explains how the complexity of human behavior, including concepts of free will, derives from a relatively small number of genes, which direct neurodevelopmental sequences. Are people free to make choices, or do genes determine behavior? Paradoxically, the answer to both questions is "yes," because of neurogenetic individuality, a new theory with profound implications. Here, author David Goldman uses judicial, political, medical, and ethical examples to illustrate that this lifelong process is guided by individual genotype, molecular and physiologic principles, as well as by randomness and environmental exposures, a combination of factors that we choose and do not choose. Written in an authoritative yet accessible style, the book includes practical descriptions of the function of DNA, discusses the scientific and historical bases of genethics, and introduces the topics of epigenetics and the predictive power of behavioral genetics. In the decade since the first edition published, knowledge of genetic influences on the neurogenetic underpinnings of behavior has been transformed by genomic technologies. Genome-Wide Association studies, for example, have revealed that hundreds of genes influence vulnerability to psychiatric disease and innate predisposition to risk-taking behaviors. This new edition has been thoroughly revised to focus on free will and its neurogenetic origins. In addition, the use of polygenic scores for behavioral prediction are discussed in-depth, reflecting the GWAS (Genome-Wide Association Study) revolution and combined use of genetic predictors in polygenic scores. Sections on epigenetics are also substantially expanded throughout, better defined, and tied to neuroplasticity and gene-environment interaction. Figures and illustrations have been added or improved throughout, and disease nosology and terminology has been updated. - Updates on the previous edition which was the First Prize winner of the 2013 BMA Medical Book Award for Basic and Clinical Sciences - Poses and resolves challenges to moral responsibility raised by modern genetics and neuroscience - Analyzes the neurogenetic origins of human behavior and free will - Features expanded sections on the neurogenetic basis of free will, polygenic risk scores, and epigenetic influence over behavior, as well as improved figures and updated terminology