The Dismal State of the Great Lakes


Book Description

"Ludwig tells powerful stories about places, people and environmental issues. He narrates with unfl inching honesty his experiences investigating and tracking down the culprits in continuing environmental contamination. He rises to meet the beauty and grace of the Great Lakes with lively tales of decades out on their waters as a researcher. This book is an indispensable part of the Great Lakes literary canon." Dave Dempsey, author of "On the Brink: The Great Lakes in the 21st Century" and "The Blanchard Connection". "Ludwig has written a monumental compendium about the largest source of fresh water in the world, a life support system whose function he reveals has been under siege. It refl ects what happened as peer reviewed science, public health, and common sense were set aside and corporate-creep infected the chambers where policy decisions are made. It also parallels the same problem where humanity is now under siege from a growing list of epidemics of endocrine-related disorders the problem fi rst reported by Ludwig and his cronies back in the early 80s." Theo Colborn, Ph.D President, The Endocrine Disruption Exchange




Trends in Levels and Effects of Persistent Toxic Substances in the Great Lakes


Book Description

`Are the Great Lakes getting better or worse?' This is the question that the public, scientists and managers are asking the International Joint Commission after a quarter-century of cooperative action by the United States and Canadian governments to clean up the Great Lakes. This volume contains papers from the workshop on Environmental Results, hosted in Windsor, Ontario, by the Great Lakes Science Advisory Board of the International Joint Commission, on September 12 and 13, 1996. The Great Lakes have been through almost a century of severe pollution from the manufacture, use and disposal of chemicals. In the 1960s wildlife biologists started to investigate the outbreaks of reproductive failure in fish-eating birds and ranch mink and to link these to exposure to organochlorine compounds. Human health researchers in the 1980s and 1990s linked growth retardation, behavioral anomalies and deficits in cognitive development with maternal consumption of Great Lakes fish prior to pregnancy. The Great Lakes became the laboratory where the theory of endocrine disruptors was first formulated. Now a group of Great Lakes scientists, hosted by the International Joint Commission, has compiled the story of the trends in the concentrations and effects of persistent toxic substances on wildlife and humans. The technical papers review the suitability of various organisms as indicators, and present the results of long-term monitoring of the concentrations and of the incidence of effects. The evidence shows that there was an enormous improvement in the late 1970s, but that in the late 1990s there are still concentrations of some persistent toxic substances that have stubbornly remained at levels that continue to cause toxicological effects.







Bald Eagles in Alaska


Book Description

An expansive collection of papers and articles from internationally recognized bald eagle experts. Presented is a complete portrait of the status and ecology of the bald eagle in Alaska.A collection of papers and articles from international bald eagle experts, which present a complete portrait of the status and ecology of the bald eagle in Alaska. Myriad topics include culture, biology, population history and status, conservation and management, the Alaskan habitat from the northern rainforest to the Aleutian Islands, attitudes from diverse groups from the Tlingit to bounty hunters, along with sound scientific data.







Ecosystem Responses to Mercury Contamination


Book Description

As rising levels of mercury in the environment pose an increasing threat of toxicity to humans and wildlife, several laws already call for industries to reduce mercury emissions at the source. Ecosystem Responses to Mercury Contamination: Indicators of Change outlines the infrastructure and methods needed to measure, monitor, and regulate the conce




Toxicity Assessment Alternatives


Book Description

Toxicity Assessment Alternatives: Methods, Issues, Opportunities contains a broad array of critical surveys, contributed by active and respected investigators, describing their research and offering updates on toxicity assessment alternatives, directions determined by current and future grant programs, opportunities for mechanistically based test methods to detect endocrine disruptor activity, the use of alternatives in the Department of Defense hazard assessment initiatives, and the issues and opportunities for validation and regulatory acceptance. Several of these advances make use oftransgenic models that reduce the time and cost of carcinogenicity testing. Others use tissue cultures for the assessment of endocrine disrupting chemicals. Cultures of human epidermal keratinocytes are applicable as models for sulfur mustard lesions, and in vitro protein denaturation is used as a chemical test for assessing the ocular and dermal irritation potential of cosmetic prod ucts. Molecular modeling is applied to explaining chemical toxicity. Commercially developed assay systems have undergone extensive evaluation by their manufacturers. Some of these await external valida tion, and others await acceptance by North American and European regulatory agencies. Toxicity Assessment Alternatives: Methods, Issues, Opportunities provides information from members of the scientific and regulatory communities on what has been achieved and what has been accepted in alternatives to animal testing.