Author : C. Buske
Publisher : Karger Medical and Scientific Publishers
Page : 76 pages
File Size : 44,44 MB
Release : 2022-11-30
Category : Medical
ISBN : 3318071951
Waldenström macroglobulinemia (WM) is a rare lymphoplasmacytic lymphoma characterized by the presence of an immunoglobulin M (IgM) monoclonal protein. WM is a chronic, indolent disease, which can remain undiagnosed for years. A better understanding of the role of signaling pathways in the development of the disease and the identification of clinical and genetic markers have driven the development of targeted therapeutic strategies, improving overall survival.
Author : S. D'Sa
Publisher : Karger Medical and Scientific Publishers
Page : 34 pages
File Size : 17,21 MB
Release : 2022-06-17
Category : Medical
ISBN : 3318071447
Waldenström macroglobulinemia (shortened to WM) is a rare blood cancer. WM usually progresses slowly; some people do not show symptoms for several years after diagnosis. A person who does not have symptoms usually does not need treatment, but active monitoring is essential so that treatment can be started as soon as it is needed. Although there is no cure for WM, different treatment options can keep the disease under control for many years in a lot of people. Eventually, the treatments tend to lose their effect. New therapies are being tested in clinical trials across the world, with promising results. Table of Contents: • What is Waldenström macroglobulinemia? How will WM affect me? Who is in my care team? What tests will I need to have? Common feelings when diagnosed • Helping yourself • Active monitoring • Starting treatment • Types of treatment • What are supportive treatments? How do I know if treatment has worked? Follow-up after treatment • When WM comes back • Research and new treatments • Understanding WM
Author : Christian Buske
Publisher : Karger Medical and Scientific Publishers
Page : 76 pages
File Size : 23,3 MB
Release : 2022-10-05
Category : Medical
ISBN : 3318067350
Author : Graham P. Collins
Publisher : Karger Medical and Scientific Publishers
Page : 188 pages
File Size : 29,20 MB
Release : 2023-07-20
Category : Medical
ISBN : 3318072869
Lymphoma can be broadly defined as a cancer of mature lymphocytes. Our understanding of the biology of normal lymphocytes and lymphoma has grown at a tremendous pace, and this is now directly translating into changes in clinical practice. This became evident with the introduction of one of the first therapeutic monoclonal antibodies into cancer medicine, the CD20-directed antibody rituximab, which has led to significant benefit for patients with B-cell lymphomas. Since then, a raft of novel agents has entered clinical practice, including targeted small molecules, antibody-drug conjugates, bispecific antibodies, and chimeric antigen receptor (CAR) T cells. This new edition of 'Fast Facts: Lymphoma' has been updated to include recent changes in our understanding of lymphoma biology as well as improvements in diagnostics and therapeutics.
Author : Karthik Ramasamy
Publisher : Karger Medical and Scientific Publishers
Page : 162 pages
File Size : 39,63 MB
Release : 2017-01-09
Category : Medical
ISBN : 1910797332
Our understanding of multiple myeloma (MM) is growing at a formidable pace, particularly in terms of risk factors and potential drug targets. Minimal residual disease (MRD) negativity is set to become the new benchmark in treatment, and cytogenetic analysis is now paving the way for personalized therapies. This second edition of 'Fast Facts: Multiple Myeloma and Plasma Cell Dyscrasias' includes: - the new IMWG SLiM CRAB criteria - the latest advances in diagnostic tests and imaging - cytogenetics and genetic profiling - induction therapy prior to SCT - new lenalidomide- and bortezomib-based regimens - second-generation proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies treatments. This Fast Facts handbook provides a comprehensive overview of MM and other plasma cell dyscrasias, from bench to bedside, presenting the pathogenesis, diagnosis and treatment in the context of daily clinical practice. Contents: • Epidemiology and etiology Predisposing conditions associated with MM • Pathophysiology of MM and MGUS • Diagnosis, staging and monitoring of multiple myeloma • Genetics and multiple myeloma • Treatment of newly diagnosed multiple myeloma • Stem cell transplantation in multiple myeloma • Relapsed and refractory multiple myeloma • Bone disease and renal complications • AL amyloidosis • Rare plasma cell dyscrasias • Supportive care
Author : Fred F. Ferri
Publisher : Elsevier Health Sciences
Page : 464 pages
File Size : 44,56 MB
Release : 2017-09-16
Category : Medical
ISBN : 0323530419
Pocket-sized for easy portability and reference, this highly practical, full-color resource provides expert guidance in the diagnosis and treatment of the dermatologic conditions most often seen in everyday practice. Veteran author Dr. Fred F. Ferri, joined by University of Colorado dermatologists James Fitzpatrick, MD and Lori Prok, MD, present this enhanced, updated edition to aid medical students, residents, practicing physicians, and allied health professionals who deal with disorders of the skin. - Devotes a section to practical dermatologic differential diagnosis, providing a quick reference to differential diagnoses of common complaints. - Covers each topic in a consistent, practical format: General Comments (definition, etiology), Keys to Diagnosis (clinical manifestations, physical examination, diagnostic tests), Differential Diagnosis, Treatment, and Clinical Pearls. - Contains new, high-quality images in a larger size for superb visual diagnostic guidance. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Author : Shirly D'Sa
Publisher : Karger Medical and Scientific Publishers
Page : 135 pages
File Size : 26,60 MB
Release : 2024-08-13
Category : Medical
ISBN : 3318073229
'Fast Facts: Marginal Zone Lymphoma' provides an overview of MZL for healthcare professionals and others with an interest in this blood cancer. It summarizes what is known about the pathophysiology of the disease, and discusses the importance of accurate diagnosis, staging, and prognosis, together with existing approaches to treatment and monitoring, including the latest evidence for new therapies in the R/R setting. With an eye to the future, it also reviews some of the therapies in development, which may ultimately improve quality of life and ensure better outcomes for patients with MZL.
Author : Ajay Singh
Publisher : Karger Medical and Scientific Publishers
Page : 146 pages
File Size : 42,76 MB
Release : 2013-06-01
Category : Medical
ISBN : 1908541180
Early detection of renal problems coupled with the appropriate therapeutic strategy can radically reduce the progressive nature of, and complications associated with, chronic kidney disease, and in many instances will result in the successful treatment of acute kidney injury. As many patients will not be seen by nephrologists, it is essential that all healthcare professionals, in hospitals and in the community, have an awareness of renal disease – the presenting signs, differential diagnoses, treatment strategies and approach to the management of complications. 'Fast Facts: Renal Disorders' is an easy-to-read, evidence-based guide to renal diseases and disorders for all doctors, nurses and medical students. It includes: • A clear explanation of proteinuria, hematuria, electrolyte imbalances and acid–base disorders • A concise summary of kidney function tests, imaging techniques and biopsy • Important questions for prompt diagnosis of acute kidney injury • Management options for chronic kidney disease and its complications • Practical guidance on the most common renal problems, including glomerulonephritis, systemic disease, UTIs and kidney stones Written by three specialists of international repute, 'Fast Facts: Renal Disorders' provides the key information required for the optimal care of renal patients. This fully updated second edition will help healthcare professionals assess, identify, treat and refer patients with renal problems appropriately. Directly applicable to the clinical setting, it is essential reading for all primary care providers, junior hospital doctors, specialist trainees, renal nurses and medical students. Contents: • Proteinuria, hematuria and renal investigations • Electrolyte disturbances and acid–base disorders • Acute kidney injury • Chronic kidney disease • Hypertension and diabetic nephropathy • Glomerulonephritis • Systemic disease • Inherited kidney disease • Urinary tract infection • Kidney stones • Urinary tract obstruction and tumors • Renal replacement therapy and transplantation
Author : David Green
Publisher : Karger Medical and Scientific Publishers
Page : 150 pages
File Size : 13,22 MB
Release : 2013-02-25
Category : Medical
ISBN : 1908541369
Most hemorrhagic problems are emergencies, requiring rapid diagnosis and prompt management to stop bleeding. In some cases, such as nose bleeds, large bruises and heavy menses, it is the clinician’s responsibility to discern whether the patient has a clinically significant bleeding disorder that may predispose to excessive or potentially serious bleeding. 'Fast Facts: Bleeding Disorders' keeps a complex subject simple and clinically oriented. The authors have made numerous updates to this second edition to ensure it provides essential information in a readily accessible format. Highlights include: • An expert overview of normal hemostasis • A clear assessment pathway, from taking an accurate history and focused clinical examination, to essential laboratory investigations • Objective criteria for diagnosing hereditary hemorrhagic telangiectasia • The latest guidelines on diagnosing and treating primary immune thrombocytopenia • A discussion of the benefits of prophylaxis in patients with hemophilia • Updated methods for evaluating and treating bleeding disorders in pregnancy • An overview of the scoring system for disseminated intravascular coagulation • Information on the latest anticoagulants and antithrombotics, including bleeding risks and strategies to control bleeding. 'Fast Facts: Bleeding Disorders' remains a comprehensive up-to-date reference that reflects the latest research and clinical guidelines. It will assist primary care providers, physician assistants, nurse-clinicians, pharmacists, residents and doctors in training as they confront the challenges of controlling bleeding in patients with hemophilia, von Willebrand disease, platelet disorders and thrombosis, or as a result of antithrombotic or anticoagulant therapy. It is a small book packed with important information, designed to swiftly improve patient treatment and outcomes. Contents: • Normal hemostasis • Assessment of bleeding symptoms • Vascular purpuras • Platelet disorders • Pharmacological hemostatic products • Hemophilia • von Willebrand disease • Uncommon congenital coagulation disorders • Liver and kidney disorders • Pregnancy • Perioperative bleeding • Disseminated intravascular coagulation • Anticoagulants and antithrombotic agents • Useful resources
Author : Wilma Barcellini
Publisher : Karger Medical and Scientific Publishers
Page : 70 pages
File Size : 44,18 MB
Release : 2023
Category : Medical
ISBN : 3318072338
Cold agglutinin disease (CAD) is a rare, autoimmune hemolytic anemia in which cold-reacting autoantibodies (cold agglutinins) bind to normal antigens on the surface of red blood cells during passage through the cooler peripheral circulation. These antibodies cause agglutination of red blood cells, leading to an immune response and premature destruction of the healthy red blood cells. The authors have written this resource to give clinicians the information they need to successfully diagnose and manage CAD in adult patients.
