Binding Fate


Book Description

Duty and loyalty come first...everything else comes second. Sent to the palace with a hardened heart, Alzerion navigates his new life amidst lessons, trainings, and rumors of a rebellion. When the rebel leader takes him, Alzerion realizes the forces at play, the lengths they will go to get what they want, and the lines he must cross. Alzerion clashes with the rebels and the demons within as relationships are tested and betrayals await. Can he save them all or will success come at a cost? Enter the world of Bachusa.




Receptor-Mediated Endocytosis


Book Description

This volume focuses exclusively on those endocytic processes that sequester proteins by a selective, receptor-mediated mechanism. In such an endocytic process, cell surface receptors specifically bind protein ligands and localize them to specialized invaginations of the plasma membrane. These regions are coated pits, so named because they are lined on the cytoplasmic face with an ordered array of the protein, clathrin. It is this 'coat' which provides their characteristic electron microscopic image. Subsequently, these regions pinch off to form coated vesicles which rapidly lose their 'coat' and then fuse with other organelles or the plasma membrane. The hallmarks of ,this process are the specific receptors, coated pits, coated vesicles and an ordered sequence of transit events leading to delivery to selected locations. Receptor recognition, specific disposition of the endocytosed ligand and the existence of recep tor-ligand complexes at highest density in coated pits define the process as selective and concentrative. This topic has received ever increasing attention during the past few years. The evolving mechanisms are especially exciting because they come at a time when the conventional views based on thermodynamic arguments suggest that proteins should not be able to cross into the cell. Receptor-mediated endocytosis, however, reconciles the view that biological membranes should be impervious to macromolecules with the evidence that certain mac romolecules do gain entrance into the cell. During the last few years this field has been stimulated by studies on the uptake and processing of low density lipoproteins (LDL) by cells.




The Crown's Fate


Book Description

The gorgeous and darkly compelling sequel to The Crown’s Game—perfect for fans of Red Queen and Shadow and Bone.A New York Times bestseller! Magic is growing, shadows are rising, and the throne is at stake… Russia is on the brink of great change. Pasha’s coronation approaches, and Vika is now the Imperial Enchanter, but the role she once coveted may be more difficult—and dangerous—than she ever expected. Pasha is grappling with his own problems—his legitimacy is in doubt, the girl he loves loathes him, and he believes his best friend is dead. When a challenger to the throne emerges—and with the magic in Russia growing rapidly—Pasha must do whatever it takes to keep his position and protect his kingdom. For Nikolai, the ending of the Crown’s Game stung deeply. Although he just managed to escape death, Nikolai remains alone, a shadow hidden in a not-quite-real world of his own creation. But when he’s given a second chance at life—tied to a dark price—Nikolai must decide just how far he’s willing to go to return to the world. With revolution on the rise, dangerous new magic rearing up, and a tsardom up for the taking, Vika, Nikolai, and Pasha must fight—or face the destruction of not only their world but also themselves.




Molecular and Cellular Iron Transport


Book Description

This text analyzes the molecular mechanisms, chemical behaviour and regulation of iron transport in biological systems and offers novel methods for the assessment of iron transport across biological membranes. It details the characteristics and consequences of iron deficiency and excess to prevent diseases affecting major organ structures and promote bodily iron homeostasis.




The Crown's Game


Book Description

"Gorgeous and richly imagined."—Sara Raasch, New York Times bestselling author of the Snow Like Ashes series "Teeming with hidden magic and fiery romance."—Sabaa Tahir, #1 New York Times bestselling author of An Ember in the Ashes Perfect for fans of Shadow and Bone and Red Queen, The Crown’s Game is a thrilling and atmospheric historical fantasy set in Imperial Russia about two teenagers who must compete for the right to become the Imperial Enchanter—or die in the process—from debut author Evelyn Skye. Vika Andreyeva can summon the snow and turn ash into gold. Nikolai Karimov can see through walls and conjure bridges out of thin air. They are enchanters—the only two in Russia—and with the Ottoman Empire and the Kazakhs threatening, the tsar needs a powerful enchanter by his side. And so he initiates the Crown’s Game, an ancient duel of magical skill—the greatest test an enchanter will ever know. The victor becomes the Imperial Enchanter and the tsar’s most respected adviser. The defeated is sentenced to death. Raised on tiny Ovchinin Island her whole life, Vika is eager for the chance to show off her talent in the grand capital of Saint Petersburg. But can she kill another enchanter—even when his magic calls to her like nothing else ever has? For Nikolai, an orphan, the Crown’s Game is the chance of a lifetime. But his deadly opponent is a force to be reckoned with—beautiful, whip smart, imaginative—and he can’t stop thinking about her. And when Pasha, Nikolai’s best friend and heir to the throne, also starts to fall for the mysterious enchantress, Nikolai must defeat the girl they both love . . . or be killed himself. As long-buried secrets emerge, threatening the future of the empire, it becomes dangerously clear . . . the Crown’s Game is not one to lose.




Federation Proceedings


Book Description

Vols. for 1942- include proceedings of the American Physiological Society.




Birth of Nomos


Book Description

This is a highly original, interdisciplinary study of the archaic Greek word nomos and its family of words. More recently used to mean simply 'law' or 'law-making', Thanos Zartaloudis draws out the richness of this fundamental term by exploring its many roots and uses over the centuries. The Birth of Nomos includes extracts from ancient sources, in both the original and English translation, including material from legal history, philosophy, philology, linguistics, ancient history, poetry, archaeology, ancient musicology and anthropology. Through a thorough analysis of these extracts, we gain a new and complete understanding of nomos and its foundational place in the Western legal tradition.







Vitamin D


Book Description

Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This second edition includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must have resource for anyone working in endocrinology, osteology, bone biology, or cancer research. *Most comprehensive, up-to-date two-volume set on Vitamin D *New chapters on squamous cell cancer, brain cancer, thyroid cancer and many more *Further sections on emerging uses for treatments of auto-immune diseases and diabetes *Over 600 illustrations and figures available on CD