Fetal Cells and Fetal Nucleic Acids in Maternal Blood
Author : Sinuhe Hahn
Publisher :
Page : 78 pages
File Size : 20,78 MB
Release : 2001
Category :
ISBN :
Author : Sinuhe Hahn
Publisher :
Page : 78 pages
File Size : 20,78 MB
Release : 2001
Category :
ISBN :
Author : Sinuhe Hahn
Publisher : Karger Medical and Scientific Publishers
Page : 145 pages
File Size : 36,79 MB
Release : 2001-01-01
Category : Medical
ISBN : 3805572220
Is noninvasive, risk-free prenatal diagnosis of fetal genetic characteristics still a fantasy, or will it soon become reality? The current status of both the leading European research groups as well as the NIH-funded NIFTY study are reported here, indicating that certain fetal genetic traits can now be examined efficiently in a noninvasive manner. Considerable focus is placed on new laser-mediated systems for the effective micro-manipulation of single fetal cells, as well as their analysis by single-cell PCR and the pitfalls to avoid when performing such analyses. Other issues addressed in depth include: novel enrichment techniques, optimal fetal cell recognition, fetal cell culture, as well as the exciting finding that fetal cell traffic is elevated in certain pregnancy-related disorders, most prominently in preeclampsia. This publication is of interest to researchers in the field, genetic counsellors, gynecologists and obstetricians, and researchers in microchimerism, transplantation and transfusion medicine.
Author : S. Hahn
Publisher :
Page : 0 pages
File Size : 49,2 MB
Release : 2001
Category : Medical
ISBN : 9783318006995
Is noninvasive, risk-free prenatal diagnosis of fetal genetic characteristics still a fantasy, or will it soon become reality? The current status of both the leading European research groups as well as the NIH-funded NIFTY study are reported here, indicating that certain fetal genetic traits can now be examined efficiently in a noninvasive manner. Considerable focus is placed on new laser-mediated systems for the effective micro-manipulation of single fetal cells, as well as their analysis by single-cell PCR and the pitfalls to avoid when performing such analyses. Other issues addressed in depth include: novel enrichment techniques, optimal fetal cell recognition, fetal cell culture, as well as the exciting finding that fetal cell traffic is elevated in certain pregnancy-related disorders, most prominently in preeclampsia. This publication is of interest to researchers in the field, genetic counsellors, gynecologists and obstetricians, and researchers in microchimerism, transplantation and transfusion medicine.
Author : Joe Leigh Simpson
Publisher :
Page : 296 pages
File Size : 23,63 MB
Release : 1994
Category : Health & Fitness
ISBN :
Several lines of evidence indicate that foetal cells - lymphocytes, nucleated red cells, trophoblasts - exist in maternal blood during pregnancy. The potential thus exists for recovering foetal cells from maternal blood and then analysing these cells for foetal genetic abnormalities. This volume explores the biology and maternal foetal transfer of the three cell types during pregnancy, the use of flow cytometry and other techniques to enrich the yield of these cells from maternal blood, the application of diagnostic techniques for identifying cytogenetic and other genetic abnormalities, and public health and other issues involved in the implementation of such testing.
Author : Peter B. Gahan
Publisher : Springer
Page : 476 pages
File Size : 15,59 MB
Release : 2014-11-18
Category : Medical
ISBN : 9401791686
DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up. In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal and premature born infant development. This volume is intended as a primer for those who are interested in entering the field of circulating nucleic acids. The areas covered in this volume include: · Background and general biology of circulating nucleic acids · Methodology · Applications of circulating nucleic acids · Quality Assurance · Ethics
Author : Yuk-Ming Dennis Lo
Publisher :
Page : 0 pages
File Size : 20,22 MB
Release : 1994
Category : Fetal cells from maternal blood
ISBN :
Author : Jacob Mørup Schlütter
Publisher :
Page : pages
File Size : 27,86 MB
Release : 2014
Category :
ISBN :
Author : Yuk-Ming Dennis Lo
Publisher :
Page : 316 pages
File Size : 33,82 MB
Release : 1994
Category : Fetal cells from maternal blood
ISBN :
Author : Shruti Bajaj
Publisher :
Page : 96 pages
File Size : 18,14 MB
Release : 1998
Category :
ISBN :
Author : Jan Cornelis Oosterwijk
Publisher :
Page : 139 pages
File Size : 35,87 MB
Release : 1998
Category :
ISBN : 9789090116846
Summary ; Samenvatting.