Fixing EPA's Broken Integrated Risk Information System, Serial No. 111-33, June 11, 2009, 111-1 Hearing, *.
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Page : pages
File Size : 24,11 MB
Release : 2010
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Author :
Publisher :
Page : pages
File Size : 24,11 MB
Release : 2010
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Author : United States. Congress. House. Committee on Science and Technology (2007). Subcommittee on Investigations and Oversight
Publisher :
Page : 144 pages
File Size : 17,45 MB
Release : 2009
Category : Law
ISBN :
Author : United States. Congress. House. Committee on Science and Technology
Publisher :
Page : pages
File Size : 45,53 MB
Release : 2010*
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Author : United States. Congress. House. Committee on Science and Technology (2007-2011). Subcommittee on Investigations and Oversight
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Page : pages
File Size : 45,14 MB
Release : 2009
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Author : National Research Council
Publisher : National Academies Press
Page : 227 pages
File Size : 28,36 MB
Release : 2014-06-25
Category : Political Science
ISBN : 0309304172
The Integrated Risk Information System (IRIS) is a program within the US Environmental Protection Agency (EPA) that is responsible for developing toxicologic assessments of environmental contaminants. An IRIS assessment contains hazard identifications and dose-response assessments of various chemicals related to cancer and noncancer outcomes. Although the program was created to increase consistency among toxicologic assessments within the agency, federal, state, and international agencies and other organizations have come to rely on IRIS assessments for setting regulatory standards, establishing exposure guidelines, and estimating risks to exposed populations. Over the last decade, the National Research Council (NRC) has been asked to review some of the more complex and challenging IRIS assessments, including those of formaldehyde, dioxin, and tetrachloroethylene. In 2011, an NRC committee released its review of the IRIS formaldehyde assessment. Like other NRC committees that had reviewed IRIS assessments, the formaldehyde committee identified deficiencies in the specific assessment and more broadly in some of EPA's general approaches and specific methods. Although the committee focused on evaluating the IRIS formaldehyde assessment, it provided suggestions for improving the IRIS process and a roadmap for its revision in case EPA decided to move forward with changes to the process. Congress directed EPA to implement the report's recommendations and then asked the National Research Council to review the changes that EPA was making (or proposing to make) in response to the recommendations. Review of EPA's Integrated Risk Information System (IRIS) Process provides an overview of some general issues associated with IRIS assessments. This report then addresses evidence identification and evaluation for IRIS assessments and discusses evidence integration for hazard evaluation and methods for calculating reference values and unit risks. The report makes recommendations and considerations for future directions. Overall, Review of EPA's Integrated Risk Information System Process finds that substantial improvements in the IRIS process have been made, and it is clear that EPA has embraced and is acting on the recommendations in the NRC formaldehyde report. The recommendations of this report should be seen as building on the progress that EPA has already made.
Author : United States. Congress. House. Committee on Science, Space, and Technology (2011). Subcommittee on Oversight
Publisher :
Page : 140 pages
File Size : 27,85 MB
Release : 2014
Category : Chemicals
ISBN :
Author : United States. Congress. House. Committee on Science and Technology (2007). Subcommittee on Investigations and Oversight
Publisher :
Page : 236 pages
File Size : 19,94 MB
Release : 2008
Category : Chemicals
ISBN :
Author : United States Government Accountability Office
Publisher : Createspace Independent Publishing Platform
Page : 90 pages
File Size : 43,96 MB
Release : 2017-09-07
Category :
ISBN : 9781976190728
The Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) contains EPA's scientific position on the potential human health effects of exposure to more than 540 chemicals. IRIS is a critical component of EPA's capacity to support scientifically sound environmental decisions, policies, and regulations. GAO was asked to examine (1) the outcome of steps EPA has taken to ensure that IRIS contains current, credible chemical risk information, to address the backlog of ongoing assessments, and to respond to new requirements from the Office of Management and Budget (OMB); and (2) the potential effects of planned changes to the IRIS assessment process on EPA's ability to ensure that IRIS provides current, credible risk information. To do this work, GAO reviewed and analyzed EPA data and interviewed officials at relevant agencies.
Author : John B. Stephenson
Publisher : DIANE Publishing
Page : 13 pages
File Size : 38,78 MB
Release : 2009-12
Category : Medical
ISBN : 1437917968
The EPA Integrated Risk Info. System (IRIS) contains EPA's scientific position on the potential human health effects of exposure to more than 540 chemicals. Toxicity assessments in the IRIS database constitute the first two critical steps of the risk assessment process. Thus, IRIS is a critical component of EPA's capacity to support scientifically sound environmental decisions, policies, and regulations. This testimony discusses: (1) the findings from a March 2008 report ¿Chemical Assessments: Low Productivity and New Interagency Review Process Limit the Usefulness and Credibility of EPA's Integrated Risk Info. System¿ and related testimonies; and (2) a preliminary evaluation of the revised IRIS assessment process EPA issued on May 21, 2009.
Author :
Publisher :
Page : 169 pages
File Size : 17,9 MB
Release : 2014
Category : Electronic books
ISBN :