Author : James Ralph Hanson
Publisher : Royal Society of Chemistry
Page : 180 pages
File Size : 28,34 MB
Release : 2001
Category : Education
ISBN : 9780854046270
Hanson introduces first-year undergraduates to the characteristic properties of functional groups. He covers general principles, the chemistry of the sigma-bond and the pi-bond, and the chemistry of aromatic compounds. Answers to the questions are in the back. c. Book News Inc.
Author : Thomas L. Lemke
Publisher :
Page : 156 pages
File Size : 45,37 MB
Release : 1988
Category : Science
ISBN :
Author : G. Denis Meakins
Publisher : Oxford University Press, USA
Page : 100 pages
File Size : 19,69 MB
Release : 1996
Category : Mathematics
ISBN :
The characteristic properties of functional groups and the methods for interconverting them are the foundations of organic chemistry; a sound grasp of these topics is essential for the aspiring chemist's journey to the higher levels of the subject. Many text-books are long and contain additional material, this text presents the chemistry of the groups in a concise and systematic form.
Author : Marc Harrold
Publisher : ASHP
Page : 405 pages
File Size : 33,65 MB
Release : 2013-01-18
Category : Medical
ISBN : 1585283649
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Author : Bruce Averill
Publisher :
Page : 1233 pages
File Size : 28,67 MB
Release : 2007
Category : Chemistry
ISBN : 9780321413703
Emphasises on contemporary applications and an intuitive problem-solving approach that helps students discover the exciting potential of chemical science. This book incorporates fresh applications from the three major areas of modern research: materials, environmental chemistry, and biological science.
Author : Robert A. Stockland, Jr.
Publisher : John Wiley & Sons
Page : 697 pages
File Size : 22,83 MB
Release : 2016-01-26
Category : Science
ISBN : 1118612809
A practical handbook for chemists performing bond forming reactions, this book features useful information on the synthesis of common functional groups in organic chemistry. • Details modern functional group synthesis through carbon-heteroelement (N, O, P, S, B, halogen) bond forming reactions with a focus on operational simplicity and sustainability. • Summarizes key and recent developments – which are otherwise scattered across journal literature – into a single source • Contains over 100 detailed preparations of common functional groups • Included 25 troubleshooting guides with suggestions and potential solutions to common problems. • Complements the text in enhanced ebook editions with tutorial videos where the author provides an introduction to microwave assisted chemistry
Author : Hrvoj Vančik
Publisher : Springer Nature
Page : 213 pages
File Size : 13,41 MB
Release : 2022-01-18
Category : Medical
ISBN : 3030924386
This textbook is designed for students of biology, molecular biology, ecology,medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays an important role. The work may also be of interest to non-professionals, as well as to teachers in high schools. The book consists of 13 chapters that cover the essentials of organic chemistry, including - basic principles of structure and constitution of organic compounds, - the elements of the nomenclature, - the concepts of the nature of chemical bond, - introductions in NMR and IR spectroscopy, - the concepts and main classes of the organic reaction mechanisms, - reactions and properties of common classes or organic compounds, - and the introduction to the chemistry of the natural organic products followed by basic principles of the reactions in living cells. This second edition includes revisions and suggestions made by the readers of the first edition and the author's colleagues. In addition, it includes substantial changes compared to the first edition. The chapter on Cycloaddition has been completed by including the other pericyclic reactions (sigmatropic rearrangements, electrocyclic reactions). The chapter on Organic Natural Products has been extended to include new section covering the principles of organic synthesis. New chapter "Organic Supramolecular and Supermolecular Structures" is added. This chapter covers the basic knowledge about the molecular recognition, supramolecular structures, and the mechanisms of the enzyme catalyzed reactions.
Author : George H. Schenk
Publisher : Elsevier
Page : 309 pages
File Size : 43,96 MB
Release : 2016-06-23
Category : Science
ISBN : 1483136078
Organic Functional Group Analysis: Theory and Development attempts to symbolize the growth in functional groups analysis by using handpicked methods. Those methods are positioned to represent as many functional groups as possible. The book begins with the author referencing books about a quantitative organic analysis. Majority of the first few chapters highlight the oximation and carbonyl method, which support portions of Chapter 2 and the book's second half. The book then discusses the hydroxyl, amino, and alkoxysilanes groups. Chapters 3 and 4 showcase the strong analytical advantages in using base catalysis and acid catalysis with the same anhydride, while Chapters 5, 6, and 7 illustrate extremely useful functional group methods that have received impetus from research. The next chapters talk about the quantitative ring opening method and Diels-Alder addition method. Succeeding studies are about various compounds and its relevant subtopics. The text provides a very great reference for undergraduates and postgraduates of chemistry and its affiliated studies.
Author :
Publisher : Elsevier
Page : 9196 pages
File Size : 41,98 MB
Release : 2004-12-16
Category : Science
ISBN : 0080523471
Comprehensive Organic Functional Group Transformations II (COFGT-II) will provide the first point of entry to the literature for all scientists interested in chemical transformations. Presenting the vast subject of organic synthesis in terms of the introduction and interconversion of all known functional groups, COFGT-II provides a unique information source documenting all methods of efficiently performing a particular transformation. Organised by the functional group formed, COFGT-II consists of 144 specialist reviews, written by leading scientists who evaluate and summarise the methods available for each functional group transformation. Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. By systematically treating each functional group in turn the work also identifies what is not known, thus pointing the way to new research areas Follows the systematic layout of the successful 1995 COFGT reference work, based on the arrangement and bonding of hetero-atoms around a central carbon atom The work will save researchers valuable time in their research as each chapter is written by experts who have critically read and reviewed the literature and presented the best methods of forming every known functional group
Author : Dennis A. Smith
Publisher : Royal Society of Chemistry
Page : 545 pages
File Size : 14,53 MB
Release : 2010
Category : Medical
ISBN : 1849730164
Written by medicinal chemists and ADMET scientists with a combined experience of over 300 years this aid to discovering drugs provides detailed coverage on absorption, distribution, metabolism, excretion and toxicology issues associated with new drugs.
