Safety Critical Systems Handbook


Book Description

Safety Critical Systems Handbook: A Straightfoward Guide to Functional Safety, IEC 61508 (2010 Edition) and Related Standards, Including Process IEC 61511 and Machinery IEC 62061 AND ISO 13849, Third Edition, offers a practical guide to the functional safety standard IEC 61508. The book is organized into three parts. Part A discusses the concept of functional safety and the need to express targets by means of safety integrity levels. It places functional safety in context, along with risk assessment, likelihood of fatality, and the cost of conformance. It also explains the life-cycle approach, together with the basic outline of IEC 61508 (known as BS EN 61508 in the UK). Part B discusses functional safety standards for the process, oil, and gas industries; the machinery sector; and other industries such as rail, automotive, avionics, and medical electrical equipment. Part C presents case studies in the form of exercises and examples. These studies cover SIL targeting for a pressure let-down system, burner control system assessment, SIL targeting, a hypothetical proposal for a rail-train braking system, and hydroelectric dam and tidal gates. - The only comprehensive guide to IEC 61508, updated to cover the 2010 amendments, that will ensure engineers are compliant with the latest process safety systems design and operation standards - Helps readers understand the process required to apply safety critical systems standards - Real-world approach helps users to interpret the standard, with case studies and best practice design examples throughout




The Safety Critical Systems Handbook


Book Description

The Safety Critical Systems Handbook: A Straightforward Guide to Functional Safety: IEC 61508 (2010 Edition), IEC 61511 (2016 Edition) & Related Guidance, Fourth Edition, presents the latest on the electrical, electronic, and programmable electronic systems that provide safety functions that guard workers and the public against injury or death, and the environment against pollution. The international functional safety standard IEC 61508 was revised in 2010, and authors David Smith and Kenneth Simpson provide a comprehensive guide to the revised standard, as well as the revised IEC 61511 (2016). The book enables engineers to determine if a proposed or existing piece of equipment meets the safety integrity levels (SIL) required by the various standards and guidance, and also describes the requirements for the new alternative route (route 2H), introduced in 2010. A number of other areas have been updated by Smith and Simpson in this new edition, including the estimation of common cause failure, calculation of PFDs and failure rates for redundant configurations, societal risk, and additional second tier guidance documents. As functional safety is applicable to many industries, this book will have a wide readership beyond the chemical and process sector, including oil and gas, machinery, power generation, nuclear, aircraft, and automotive industries, plus project, instrumentation, design, and control engineers. - Provides the only comprehensive guide to IEC 61508, updated to cover the 2010 amendments, that will ensure engineers are compliant with the latest process safety systems design and operation standards - Addresses the 2016 updates to IEC 61511 to helps readers understand the processes required to apply safety critical systems standards and guidance - Presents a real-world approach that helps users interpret new standards, with case studies and best practice design examples throughout




The Safety Critical Systems Handbook


Book Description

The Safety Critical Systems Handbook: A Straightforward Guide to Functional Safety: IEC 61508 (2010 Edition), IEC 61511 (2015 Edition) and Related Guidance, Fifth Edition presents the latest guidance on safety-related systems that guard workers and the public against injury and death, also discussing environmental risks. This comprehensive resource has been fully revised, with additional material on risk assessment, cybersecurity, COMAH and HAZID, published guidance documents/standards, quantified risk assessment and new worked examples. The book provides a comprehensive guide to the revised IEC 61508 standard as well as the 2016 IEC 61511. This book will have a wide readership, not only in the chemical and process industries, but in oil and gas, power generation, avionics, automotive, manufacturing and other sectors. It is aimed at most engineers, including those in project, control and instrumentation, design and maintenance disciplines. - Provides the only comprehensive guide to IEC 61508 and 61511 (updated for 2016) that ensures engineers are compliant with the latest process safety systems design and operation standards - Presents a real-world approach that helps users interpret the standard, with new case studies and best practice design examples using revised standards - Covers applications of the standard to device design




Safety and Health for Engineers


Book Description

SAFETY AND HEALTH FOR ENGINEERS A comprehensive resource for making products, facilities, processes, and operations safe for workers, users, and the public Ensuring the health and safety of individuals in the workplace is vital on an interpersonal level but is also crucial to limiting the liability of companies in the event of an onsite injury. The Bureau of Labor Statistics reported over 4,700 fatal work injuries in the United States in 2020, most frequently in transportation-related incidents. The same year, approximately 2.7 million workplace injuries and illnesses were reported by private industry employers. According to the National Safety Council, the cost in lost wages, productivity, medical and administrative costs is close to 1.2 trillion dollars in the US alone. It is imperative—by law and ethics—for engineers and safety and health professionals to drive down these statistics by creating a safe workplace and safe products, as well as maintaining a safe environment. Safety and Health for Engineers is considered the gold standard for engineers in all specialties, teaching an understanding of many components necessary to achieve safe workplaces, products, facilities, and methods to secure safety for workers, users, and the public. Each chapter offers information relevant to help safety professionals and engineers in the achievement of the first canon of professional ethics: to protect the health, safety, and welfare of the public. The textbook examines the fundamentals of safety, legal aspects, hazard recognition and control, the human element, and techniques to manage safety decisions. In doing so, it covers the primary safety essentials necessary for certification examinations for practitioners. Readers of the fourth edition of Safety and Health for Engineers readers will also find: Updates to all chapters, informed by research and references gathered since the last publication The most up-to-date information on current policy, certifications, regulations, agency standards, and the impact of new technologies, such as wearable technology, automation in transportation, and artificial intelligence New international information, including U.S. and foreign standards agencies, professional societies, and other organizations worldwide Expanded sections with real-world applications, exercises, and 164 case studies An extensive list of references to help readers find more detail on chapter contents A solution manual available to qualified instructors Safety and Health for Engineers is an ideal textbook for courses in safety engineering around the world in undergraduate or graduate studies, or in professional development learning. It also is a useful reference for professionals in engineering, safety, health, and associated fields who are preparing for credentialing examinations in safety and health.




Definitive Guide to Arm Cortex-M23 and Cortex-M33 Processors


Book Description

The Definitive Guide to Arm® Cortex®-M23 and Cortex-M33 Processors focuses on the Armv8-M architecture and the features that are available in the Cortex-M23 and Cortex- M33 processors. This book covers a range of topics, including the instruction set, the programmer's model, interrupt handling, OS support, and debug features. It demonstrates how to create software for the Cortex-M23 and Cortex-M33 processors by way of a range of examples, which will enable embedded software developers to understand the Armv8-M architecture. This book also covers the TrustZone® technology in detail, including how it benefits security in IoT applications, its operations, how the technology affects the processor's hardware (e.g., memory architecture, interrupt handling, etc.), and various other considerations in creating secure software. - Presents the first book on Armv8-M Architecture and its features as implemented in the Cortex-M23 and Cortex-M33 processors - Covers TrustZone technology in detail - Includes examples showing how to create software for Cortex-M23/M33 processors




A Comprehensive Guide to Toxicology in Nonclinical Drug Development


Book Description

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. - Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy - Includes the latest international guidelines for nonclinical toxicology in both small and large molecules - Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology




Artificial Intelligence in Daily Life


Book Description

Given the exponential growth of Artificial Intelligence (AI) over the past few decades, AI and its related applications have become part of daily life in ways that we could never have dreamt of only a century ago. Our routines have been changed beyond measure by robotics and AI, which are now used in a vast array of services. Though AI is still in its infancy, we have already benefited immensely. This book introduces readers to basic Artificial Intelligence concepts, and helps them understand the relationship between AI and daily life. In the interest of clarity, the content is divided into four major parts. Part I (AI Concepts) presents fundamental concepts of and information on AI; while Part II (AI Technology) introduces readers to the five core AI Technologies that provide the building blocks for various AI applications, namely: Machine Learning (ML), Data Mining (DM), Computer Vision (CV), Natural Languages Processing (NLP), and Ontology-based Search Engine (OSE). In turn, Part III (AI Applications) reviews major contemporary applications that are impacting our ways of life, working styles and environment, ranging from intelligent agents and robotics to smart campus and smart city projects. Lastly, Part IV (Beyond AI) addresses related topics that are vital to the future development of AI. It also discusses a number of critical issues, such as AI ethics and privacy, the development of a conscious mind, and autonomous robotics in our daily lives.




Safety Engineering in the Oil and Gas Industry


Book Description

When accidents occur in the oil and gas industry, the impacts can be profound. Serious injury or death to workers, environmental disasters and colossal costs for insurance or clean ups make the industry a hazardous one to operate in. Disasters become major news events such as the Prestige oil spill, Piper Alpha, Exxon Valdez oil spill and Deepwater Horizon. A move towards improving the health and safety of the industry is underway. This book emphasizes controlling, managing, and mitigating the risk of hazards in the oil and gas industry, increasing safety, and protecting the environment by identifying the hazards in the oil and gas industry through safety engineering techniques and management methods. Safety Engineering in the Oil and Gas Industry discusses how to improve safety and reliability in the oil and gas industry so that hazards can be reduced to the lowest level feasible. It covers the techniques needed to operate safely in an oil and/or gas industry setting, the standards that should be adhered to, the impacts of PPE, fire and explosions, equipment and infrastructure failures and storage and reliability engineering, amongst many other topics. This book is written in an easy-to-read and appealing style and multiple-choice questions are included to help with learning and understanding the concepts included. Underpinned by real life case studies and examples, this book aims to allow readers to consider how they can reduce the costs associated with bad safety practices to their business through maintained and consistent health, safety and environmental (HSE) standards. This book is a must-read for any student or professional studying or working in the oil and gas industries. It also has additional appeal to those with an academic or professional interest in occupational health and safety, civil engineering, offshore engineering and maritime engineering.




Fire Risk Management


Book Description

FIRE RISK MANAGEMENT Practical methodologies to develop holistic and comprehensive fire safety strategies for buildings and industrial assets In Fire Risk Management: Principles and Strategies for Buildings and Industrial Assets, a team of distinguished authors delivers an incisive combination of risk management principles and fire safety assessment methods that offers practical strategies and workflows to prevent and mitigate today’s complex fire scenarios. The book summarizes modern, risk-based approaches to fire safety, discussing fire safety objectives in terms of functional statements, performance requirements, and detailed protection measures for buildings and industrial assets towards the development of a fire safety case to timely manage risk with a systematic and structured approach throughout the life cycle of the asset. The authors introduce the fundamentals of fire safety and design principles before moving on to discuss topics like fire risk assessment methods, risk profiles, risk mitigation, safety management and performance, and protective layers and controls. Fire Risk Management presents practical methods, often borrowed from those successfully used in other domains, that can be defined, shared, and communicated with multiple stakeholders from different backgrounds and with different needs and perspectives. Readers will also find: A code-neutral examination of fire safety principles that is independent of local regulations Discussions of key principle standards, including NFPA 550 and ISO 45001, and guidelines on fire risk assessment Practical explorations that connect theory with practice in the real world In-depth case studies that walk readers through fire risk management strategies for railway stations, warehouse storage facilities, heritage buildings, renewable energy installations, and process industry plants Perfect for fire safety practitioners, engineers, and other stakeholders involved in the design and operation of buildings and industrial assets, Fire Risk Management: Principles and Strategies for Buildings and Industrial Assets will also earn a place in the libraries of facility owners and operators, safety systems managers, occupational health and safety professionals, and code officials.




Smart Manufacturing


Book Description

Research efforts in the past ten years have led to considerable advances in the concepts and methods of smart manufacturing. Smart Manufacturing: Concepts and Methods puts these advances in perspective, showing how process industries can benefit from these new techniques. The book consolidates results developed by leading academic and industrial groups in the area, providing a systematic, comprehensive coverage of conceptual and methodological advances made to date. Written by leaders in the field from around the world, Smart Manufacturing: Concepts and Methods is essential reading for graduate students, researchers, process engineers, and managers. It is complemented by a companion book titled Smart Manufacturing: Applications and Case Studies, which covers the applications of smart manufacturing concepts and methods in process industries and beyond. - Takes a process-systems engineering approach to design, monitoring, and control of smart manufacturing systems - Brings together the key concepts and methods of smart manufacturing, including the advances made in the past decade - Includes coverage of computation methods for process optimization, control, and safety, as well as advanced modelling techniques