Fundamentals of Heterocyclic Chemistry


Book Description

Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters




Introduction to Heterocyclic Chemistry


Book Description

A unique approach to a core topic in organic chemistry presented by an experienced teacher to students and professionals Heterocyclic rings are present in the majority of known natural products, contributing to enormous structural diversity. In addition, they often possess significant biological activity. Medicinal chemists have embraced this last property in designing most of the small molecule drugs in use today. This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic systems. Introductory Heterocyclic Chemistry offers in-depth chapters covering naturally occurring heterocycles; properties of aromatic heterocycles; π-deficient heterocycles; π-excessive heterocycles; and ring transformations of heterocycles. It then offers an overview of 1,3-dipolar cycloadditions before finishing up with a back-to-basics section on nitriles and amidines. Presents a conversational approach to a fundamental topic in organic chemistry teaching Offers a unique look at this core organic chemistry topic via important naturally occurring and/or biologically active heterocycles Based on the author's many years of class lectures for teaching at the undergraduate and graduate level as well as pharmaceutical-industry courses Clear, concise, and accessible for advanced students of chemistry to gain a fundamental understanding of the basics of heterocyclic chemistry Introductory Heterocyclic Chemistry is an excellent text for undergraduate and graduate students as well as chemists in industrial environments in chemistry, pharmacy, medicinal chemistry, and biology.




Heterocyclic Chemistry


Book Description

Explores the fundamentals of heterocyclic chemistry, including importance, classification and nomenclature of heterocyclic compounds. The book discusses the chemistry of three-membered heterocyclic compounds, four-membered heterocyclic compounds, five membered heterocyclic compounds, and six-membered heterocyclic compounds.




Heterocyclic Chemistry At A Glance


Book Description

This expanded second edition provides a concise overview of the main principles and reactions of heterocyclic chemistry for undergraduate students studying chemistry and related courses. Using a successful and student-friendly "at a glance" approach, this book helps the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The chapters are thoroughly revised and updated with references to books and reviews; extra examples and student exercises with answers online; and color diagrams that emphasize exactly what is happening in the reaction chemistry depicted.




The Chemistry of Heterocycles


Book Description

This classical textbook in the best sense of the word is now completely revised, updated and with more than 40% new content. The approved ordering system according to the ring size of the heterocycles has been retained, while the important chapter on 'Problems and their Solutions' has been almost completely renewed by introduction of up-to-date scientific exercises, resulting in a great tool for self-testing and exams. There was maintained a chapter on nomenclature and a helpful index of name reactions. With approximately 1,000 new literature citations, this book remains a brilliant gateway to modern heterocyclic science for master and graduate students, as well as PhDs and researchers entering the field. 'If you want quick information about the basic (or acidic!) properties of a heterocycle, some interesting facts, or an assorted few ways of making it, this book provides a welcoming, accurate, and concise introduction.' Angewandte Chemie IE 'Eicher and Hauptmann provide an up to date introduction to the field for the advanced undergraduate and graduate students. ... The book is carefully produced to a very high standard.' European Journal of Medicinal Chemistry




Fundamentals of Industrial Chemistry


Book Description

This book discusses the connectivity between major chemicals, showing how a chemical is made along with why and some of the business considerations. The book helps smooth a student’s transition to industry and assists current professionals who need to understand the larger picture of industrial chemistry principles and practices. The book: Addresses a wide scope of content, emphasizing the business and polymer / pharmaceutical / agricultural aspects of industrial chemistry Covers patenting, experimental design, and systematic optimization of experiments Written by an author with extensive industrial experience but who is now a university professor, making him uniquely positioned to present this material Has problems at the end of chapters and a separate solution manual available for adopting professors Puts chemical industry topics in context and ties together many of the principles chemistry majors learn across more specific courses




Heterocyclic Organic Corrosion Inhibitors


Book Description

Heterocyclic Organic Corrosion Inhibitors: Principles and Applications aims to comprehend the synthesis and application of organic heterocyclic compounds as corrosion inhibitors in various corrosive environments. Considering the high importance of corrosion inhibitor development for different industries, the book provides the fundamentals and most recent advancements in this field. The book is an indispensable reference tool for industrialists and academicians working in the field of corrosion protection. - Provides a systematic overview of fundamentals and current advancements - Acts as a primary reference for beginner researchers in this arena - Presents a handy reference tool to different chemical industries - Covers fundamentals, industrial applications and most recent advancements in this area




Aromatic Chemistry


Book Description

All the basic principles of this important topic are clearly presented here in an account which takes as examples many compounds of industrial and biological significance. Consideration is given to the structure, reactions, and properties of benzene and classes of aromatic compounds derived from it, and topics such as thermodynamic versus kinetic control and pericyclic reactions are introduced. The text also covers polycyclic arenes and the small and large ring systems which are embraced by the wider definition of aromaticity.




Fundamentals of Medicinal Chemistry


Book Description

Provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style. The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs, pharmacokinetics and drug metabolism, The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing the final product. The text assumes little in the way of prior biological knowledge. relevant biology is included through biological topics, examples and the Appendices. Incorporates summary sections, examples, applications and problems Each chapter contains an additional summary section and solutions to the questions are provided at the end of the text Invaluable for undergraduates studying within the chemical, pharmaceutical and life sciences.




Chemistry for Pharmacy Students


Book Description

"This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read." –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules