The Work of the Digestive Glands
Author : Ivan Petrovich Pavlov
Publisher :
Page : 252 pages
File Size : 32,84 MB
Release : 1902
Category : Digestion
ISBN :
Secretin, Cholecystokinin, Pancreozymin and Gastrin
Author : J. Erik Jorpes
Publisher : Springer
Page : 376 pages
File Size : 15,8 MB
Release : 1973-07-30
Category : Medical
ISBN : 9783540059523
Book Description
In the beginning of this century physiology witnessed the creation of a new concept, the hormonal regulation of the work of the digestive organs. It was found that such essential functions as the flow of pancreatic juice and emptying of bile into the intestine were regulated by two hormones, secretin and cholecystokinin, respectively. Already in 1925 French authors attempted to measure the functional capacity of the exocrine pancreas by means of stimulation with secretin. The use fulness of the secretin test in this connection was definitely established by Scandinavian workers in the 1930's. In spite of the difficulties in obtaining secretin American authors succeeded in keeping the interest in the secretin test alive. The development in the 1950's of counter-current, ion exchange and chromato graphic techniques offered new possibilities in this field. The intestinal hormones were known to be relatively low molecular peptides and these could now be isolated in pure form. Thus secretin was isolated in 1961, and cholecystokinin in 1964. The newly developed methods for peptide analysis likewise soon brought us full information about the primary structure of the peptides. Gastrin, the specific stimulant of the gastric acid secretion, which was discovered in 1905 and acknowledged as a hormone in 1938, was the first of the gastrointestinal hormones for which the structure became known. This was in 1964. Synthesis soon followed. These developments are reviewed in the first chapter of the present volume.
Regulation of Gastrointestinal Mucosal Growth
Author : Rao N. Jaladanki
Publisher : Biota Publishing
Page : 150 pages
File Size : 21,96 MB
Release : 2016-11-30
Category : Medical
ISBN : 1615047352
Book Description
The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is regulated by the same hormones that alter metabolism in other tissues, but the gastrointestinal mucosa also responds to host events triggered by the ingestion and presence of food within the digestive tract. These gut hormones and peptides regulate the growth of the exocrine pancreas, gallbladder epithelium, and the mucosa of the oxyntic gland region of the stomach and the small and large intestines. Luminal factors, including nutrients or other dietary factors, secretions, and microbes that occur within the lumen and distribute over a proximal-to-distal gradient, are also crucial for maintenance of normal gut mucosal regeneration and could explain the villous-height-crypt-depth gradient and variety of adaptation, since these factors are diluted, absorbed, and destroyed as they pass down the digestive tract. Recently, intestinal stem cells, cellular polyamines, and noncoding RNAs are shown to play an important role in the regulation of gastrointestinal mucosal growth under physiological and various pathological conditions. In this book, we highlight key issues and factors that control gastrointestinal mucosal growth and homeostasis, with special emphasis on the mechanisms through which epithelial renewal and apoptosis are regulated at the cellular and molecular levels.
Fundamentals of Body MRI E-Book
Author : Christopher G. Roth
Publisher : Elsevier Health Sciences
Page : 402 pages
File Size : 50,44 MB
Release : 2011-08-11
Category : Medical
ISBN : 1455712752
Book Description
Fundamentals of Body MRI—a new title in the Fundamentals of Radiology series—explains and defines key concepts in body MRI so you can confidently make radiologic diagnoses. Dr. Christopher G. Roth presents comprehensive guidance on body imaging—from the liver to the female pelvis—and discusses how physics, techniques, hardware, and artifacts affect results. This detailed and heavily illustrated reference will help you effectively master the complexities of interpreting findings from this imaging modality. Master MRI techniques for the entirety of body imaging, including liver, breast, male and female pelvis, and cardiovascular MRI. Avoid artifacts thanks to extensive discussions of considerations such as physics and parameter tradeoffs. Grasp visual nuances through numerous images and correlating anatomic illustrations.
Gastrin
Author : Morton I. Grossman
Publisher : Univ of California Press
Page : 427 pages
File Size : 29,79 MB
Release : 2023-11-10
Category :
ISBN : 0520324781
Book Description
Defining Physiology: Principles, Themes, Concepts. Volume 2
Author : Hwee Ming Cheng
Publisher : Springer Nature
Page : 104 pages
File Size : 14,55 MB
Release : 2021-01-12
Category : Medical
ISBN : 3030622851
Book Description
This second volume of Defining Physiology: Principles, Themes, Concepts. continues on the same format as the first. In this new release, a selection of 44 essential topics in each major organ system is defined, then major themes, concept and principles surrounding these words in their physiologic scenarios are elaborated. For each keyword, a question is posed at the end of the text to test for a better understanding of the associated physiology of nervous and gastrointestinal systems. This book presents an easy reference guide for those just starting out in the area of physiology and for those who are interested in clear and succinct definitions of key terms.
Canine and Feline Gastroenterology
Author : Robert J. Washabau
Publisher : Elsevier Health Sciences
Page : 1017 pages
File Size : 13,27 MB
Release : 2012-04-27
Category : Medical
ISBN : 143770302X
Book Description
A comprehensive reference standard for the discipline, Canine and Feline Gastroenterology covers the biology, pathobiology, and diagnosis and treatment of diseases of the gastrointestinal, pancreatic, and hepatobiliary systems. An international team of experts, including 85 authors from 17 different countries, led by Robert Washabau and Michael Day, covers everything from minor problems such as adverse food reactions to debilitating inflammatory, infectious, metabolic, and neoplastic diseases of the digestive system. This authoritative text utilizes an evidence-based approach to reflect the latest science and research, complemented by principles of problem solving, algorithms to improve clinical diagnoses, and extensive full-color illustrations. For generalists and specialists alike, this gastroenterology reference should be part of every serious practitioner's professional library. - A comprehensive, 928-page reference standard covers the discipline of canine and feline gastroenterology. - An international focus is provided by 85 authors from 17 different countries, including renowned experts in veterinary gastroenterology, internal medicine, pathology, clinical pathology, radiology, and infectious disease. - Coverage of the entire breadth and depth of gastroenterology ranges from biology to pathobiology, as well as diagnosis and treatment of diseases of the gastrointestinal, pancreatic, and hepatobiliary systems. - Current information on GI microflora, immunology, cellular growth, and systems integration provides a foundation for treating clinical problems. - Coverage of diseases in dogs and cats includes the oral cavity, esophagus, stomach, small intestine, large intestine, colon, anorectum, liver and biliary tract, exocrine pancreas, peritoneum, and associated vasculature. - A focus on patient management examines the full range of procedures and techniques essential to diagnosis and treatment from clinical signs and diagnosis to nutritional support and pharmacologic management of disease. - Clear explanations of current diagnostic modalities include laboratory tests, molecular methods, diagnostic imaging, endoscopy, and histopathology, also showing how to interpret and utilize results. - A strong clinical approach emphasizes need-to-know information for managing the common and not-so-common G.I. clinical problems of everyday practice. - Full-color photographs and illustrations depict concepts, conditions, and procedures. - An evidence-based medicine perspective reflects the latest research as well as the modern practice of veterinary medicine. - Logical, coherent, and consistent internal organization makes this a reader-friendly edition. - Problem-based algorithms help in diagnosing every G.I. clinical problem from A to Z. - A stand-alone section on the pharmacologic approach to G.I. disease offers quick and easy drug reference.
Secretin, Cholecystokinin, Pancreozymin and Gastrin
Author : J. Erik Jorpes
Publisher : Springer Science & Business Media
Page : 385 pages
File Size : 32,73 MB
Release : 2013-06-29
Category : Medical
ISBN : 3642807046
Book Description
In the beginning of this century physiology witnessed the creation of a new concept, the hormonal regulation of the work of the digestive organs. It was found that such essential functions as the flow of pancreatic juice and emptying of bile into the intestine were regulated by two hormones, secretin and cholecystokinin, respectively. Already in 1925 French authors attempted to measure the functional capacity of the exocrine pancreas by means of stimulation with secretin. The use fulness of the secretin test in this connection was definitely established by Scandinavian workers in the 1930's. In spite of the difficulties in obtaining secretin American authors succeeded in keeping the interest in the secretin test alive. The development in the 1950's of counter-current, ion exchange and chromato graphic techniques offered new possibilities in this field. The intestinal hormones were known to be relatively low molecular peptides and these could now be isolated in pure form. Thus secretin was isolated in 1961, and cholecystokinin in 1964. The newly developed methods for peptide analysis likewise soon brought us full information about the primary structure of the peptides. Gastrin, the specific stimulant of the gastric acid secretion, which was discovered in 1905 and acknowledged as a hormone in 1938, was the first of the gastrointestinal hormones for which the structure became known. This was in 1964. Synthesis soon followed. These developments are reviewed in the first chapter of the present volume.
Basic Physiology for Anaesthetists
Author : David Chambers
Publisher : Cambridge University Press
Page : 469 pages
File Size : 32,34 MB
Release : 2019-07-25
Category : Medical
ISBN : 1108463991
Book Description
Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.
The Exocrine Pancreas
Author : Stephen Pandol
Publisher : Morgan & Claypool Publishers
Page : 66 pages
File Size : 12,84 MB
Release : 2011
Category : Medical
ISBN : 1615041389
Book Description
The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.
