Book Description
"The majority of the chapters of this volume are based on the papers read in a Symposium on the "GEP Endocrine System" held on 11 and 12 February, 1972, at Ikaho, Japan."
Author : Tsuneo Fujita
Publisher :
Page : 214 pages
File Size : 47,62 MB
Release : 1974
Category : Alimentary canal
ISBN :
"The majority of the chapters of this volume are based on the papers read in a Symposium on the "GEP Endocrine System" held on 11 and 12 February, 1972, at Ikaho, Japan."
Author : Tsuneo Fujita
Publisher : Springer Science & Business Media
Page : 373 pages
File Size : 11,87 MB
Release : 2012-12-06
Category : Medical
ISBN : 4431680667
The regulation of the organism has traditionally been ascribed to two distinct systems-the nervous and the endocrine. Though coordination between the two systems has been acknowledged, researchers and authors have tended to deal with them as comprising separate categories of cells involved in different activities. With this approach, a given regulatory mechanism would be evaluated as to whether it should be accounted for by nervous or endocrine functions. The past 15 years, however, have witnessed numerous important discoveries and conceptual developments concerning the morphological, physiological, and bio chemical relations between the nervous and endocrine systems. Advances in im munocytochemical studies have revealed that there are a wide variety of messenger substances that function in both regulatory systems. As a result, researchers have been stimulated to investigate neuronlike properties of endocrine cells and, con versely, endocrine or secretory features of neurons. It has thus become obvious that the rigidities in the classic criteria of neurotransmitters and hormones may rather impede further advances in these research fields. The activities of neurons are no longer evaluated simply in terms of EPSP, IPSP, and the release of classic trans mitters such as acetylcholine, noradrenaline, and GABA. Hormonal actions are no longer analyzed solely with regard to concentrations of classic aminic and peptidic hormones in the systemic blood circulation. The concept of the paraneuron, which we proposed in 1975, has become one of the theoretical bases for the development of this trend of study.
Author : Stephen Pandol
Publisher : Morgan & Claypool Publishers
Page : 66 pages
File Size : 36,34 MB
Release : 2011
Category : Medical
ISBN : 1615041389
The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.
Author : W.D. Travis
Publisher : Springer Science & Business Media
Page : 139 pages
File Size : 19,16 MB
Release : 2012-12-06
Category : Medical
ISBN : 3642600492
with contributions by Pathologists from 14 Countries
Author : F. T. Bosman
Publisher : International Agency for Research on Cancer
Page : 424 pages
File Size : 12,29 MB
Release : 2010-10-15
Category : Medical
ISBN :
"The WHO Classification of Tumours of the Digestive System presented in this book reflects the views of a Working Group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, December 10-12, 2009"--P. [5].
Author : Hans G. Beger
Publisher : John Wiley & Sons
Page : 1218 pages
File Size : 22,85 MB
Release : 2018-04-23
Category : Medical
ISBN : 1119188393
This brand new updated edition of the most comprehensive reference book on pancreatic disease details the very latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known disorders. Included for the first time, are two brand new sections on the key areas of Autoimmune Pancreatitis and Benign Cystic Neoplasms. In addition, this edition is filled with over 500 high-quality illustrations, line drawings, and radiographs that provide a step-by-step approach to all endoscopic techniques and surgical procedures. Each of these images can be downloaded via an online image bank for use in scientific presentations. Every existing chapter in The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition has been thoroughly revised and updated to include the many changes in clinical practice since publication of the current edition. The book includes new guidelines for non-surgical and surgical treatment; new molecular biologic pathways to support clinical decision making in targeted treatment of pancreatic cancer; new minimally invasive surgical approaches for pancreatic diseases; and the latest knowledge of neuroendocrine tumors and periampullary tumors. The most encyclopedic book on the pancreas—providing outstanding and clear guidance for the practicing clinician Covers every known pancreatic disorder in detail including its anatomy, physiology, pathology, pathophysiology, diagnosis, and management Completely updated with brand new chapters Over 500 downloadable illustrations An editor and author team of high international repute who present global best-practice The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition is an important book for gastroenterologists and gastrointestinal surgeons worldwide.
Author : Stephen Robert Bloom
Publisher :
Page : 640 pages
File Size : 33,78 MB
Release : 1981
Category : Gastrointestinal hormones
ISBN :
Author : Alexander L. Shifrin
Publisher : Springer Nature
Page : 1117 pages
File Size : 21,96 MB
Release : 2022-01-19
Category : Medical
ISBN : 3030847373
Every surgical subspecialty has been rapidly developing with establishment of the board certification. The Division of Endocrine Surgery (DES) of the European Board of Surgery has defined the curriculum for Endocrine Surgery to include thyroid, parathyroid, adrenal and GEP-NET surgery, and handles accreditation in Endocrine Surgery. The first examinations in Endocrine Surgery in Europe have been introduced in 2003. The main goal of the exam is to maintain a uniform and high standard of endocrine surgical professionalism across the Europe. This book was completed with the expectation that it would benefit all European surgeons looking to be certified in Endocrine Surgery. Additionally, surgeons from the United States and other non-EU countries we hope will also benefit from this book. There is a need for a specialized book that reviews evidence based endocrine surgery that aligns itself with current curriculum standards in the field. The book contains knowledge that is expected to be known on the board examination of the DES. In general, chapters start with a patient’s case followed by questions. The subsequent comprehensive yet concise main text provides all the information needed for a successful DES exam and cites important references. After the patient case and questions, the text goes on to define the condition, the standard of care approach to establish the diagnosis, perform diagnostic tests of choice, review evidence-based treatment options including medical therapy, preparation for surgery. The chapters conclude with follow up care and long term outcomes. The topics discussed within this book closely follow the curriculum of the European Board of Surgery Examination. Written by experts in the field, Endocrine Surgery Comprehensive Board Exam Guide is a valuable source of preparation for the Endocrine Surgery examination and brings Endocrine Surgery to a higher level of expertise by helping to raise the standard of training for future endocrine surgeons.
Author : Georgios S. Limouris
Publisher : Springer Nature
Page : 265 pages
File Size : 28,22 MB
Release : 2021-05-30
Category : Medical
ISBN : 3030707733
This book describes in detail a clinical project that reveals the tumoricidal efficacy of Auger and internal conversion electrons, emitted from n.c.a. 111In and implemented in oncology as a treating armamentarium for peptide receptor radionuclide therapy (PRRT), targeting small size (ø ≤ 20 mm) tumors and micro-metastases. The keen interest in n.c.a. 111In began when it was observed that its Auger electron emission could be highly radiotoxic, due to its high LET when it decayed in the vicinity of cellular DNA. The somatostatin analog octreotide, labeled with [111In-diethylenetriaminepentaacetic acid (DTPA0-D-Phe1)] is an established diagnostic agent for the imaging of somatostatin receptor-positive neuro- (or non-neuro) endocrine tumors. It relies on receptor-mediated binding, internalization and installation in the lysosomes in the proximity of the nucleus; administered in large doses, loco-regionally, via the feeding artery of solid tumors, can be highly radiotoxic if they over-express somatostatin receptors, mainly of the sst2 histotype. The book compares the results between i.v. and i.a. implementation in more than 80 patients after over 800 i.a. infusions in neuroendocrine tumors, meningiomas, paragangliomas and colorectal carcinomas in a single Institute (Aretaieion University Hospital) and encourages the i.a. way, leading to “tumor melting”, while minimizing the toxicity to healthy peritumoral liver tissue and critical organs (kidneys and bone marrow). The volume is an invaluable tool for nuclear medicine physicians, interventional radiologists and oncologists dealing with radiopeptide therapies.
Author : Ricardo V. Lloyd
Publisher : WHO Classification of Tumours
Page : 0 pages
File Size : 34,55 MB
Release : 2017
Category : Medical
ISBN : 9789283244936
The WHO Classification of Tumours of Endocrine Organs is the 10th volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies evaluating response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, pathology, genetics, prognosis, and predictive factors. The book, prepared by 166 authors from 25 countries, contains more than 700 color images and tables and more than 3100 references.