Author : Korise Elaine Rasmusson
Publisher :
Page : 392 pages
File Size : 25,56 MB
Release : 1991
Category :
ISBN :
Author : Henry Erlich
Publisher : Springer
Page : 246 pages
File Size : 39,60 MB
Release : 2015-12-31
Category : Science
ISBN : 1349202355
This is an introduction to the methods and applications of polymerase chain reaction (PCR) technology, a technology developed by Erlich's group at Cetus and Cetus, and is expected to be used in all biology laboratories worldwide within the next few years.
Author :
Publisher : Academic Press
Page : 0 pages
File Size : 18,83 MB
Release : 2019-05-21
Category : Science
ISBN : 9780128163634
Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research.
Author : Pawel Michalak
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 36,93 MB
Release : 2013
Category : Science
ISBN : 9781626183896
The origin of species, or speciation, the "mystery of mysteries", as Charles Darwin called it, is an issue at the very heart of evolutionary biology, critical to understanding the mechanisms behind the great diversity of life around us. This book is centred around three major research areas: (1) biodiversity patterns in relation to speciation scenarios; (2) mechanisms that produce pre- and postzygotic reproductive isolation and adaptive divergence; as well as (3) genetics, epigenetics, and genomics of speciation. Being a mishmash of new ideas, reviews, conventional and nonconventional case studies, this collection demonstrates more than anything how research can benefit from integration of traditionally divergent disciplines, such as biogeography, paleontology, taxonomy, molecular genetics, proteomics, and genomics.
Author : J. F. McDonald
Publisher : Springer Science & Business Media
Page : 314 pages
File Size : 46,79 MB
Release : 2000-07-31
Category : Medical
ISBN : 9780792363064
Once considered merely `selfish' or `parasitic' DNA, transposable elements are today recognized as being of major biological significance. Not only are these elements a major source of mutation, they have contributed both directly and indirectly to the evolution of genome structure and function. On October 8-10, 1999, 100 molecular biologists and evolutionists representing 11 countries met on the campus of The University of Georgia in Athens for the inaugural Georgia Genetics Symposium. The topics of presentations ranged from how the elements themselves have evolved to the impact transposable elements have had on the evolution of their host genomes. The papers in this volume therefore represent state-of-the-art thinking, by leading world experts in the field, on the evolutionary significance of transposable elements.
Author : Max E. Gottesman
Publisher :
Page : 240 pages
File Size : 34,8 MB
Release : 1992
Category : Science
ISBN :
Mechanisms of Eukaryotic DNA Recombination is a collection of papers that discusses advances in eukaryotic genetic recombination. Papers address issues in eukaryotic genetic recombination, particularly DNA integration in mammalian genomes, genetic recombination in Drosophila or Caenorhabditis; the manipulation of the mouse genome; genome organization; and genetic recombination in protozoa. One paper discusses chromatid interactions during intrachromosomal recombination in mammalian cells, namely, intrachromatid and sister chromatid. Another paper analyzes the implication for chromosomal recomb ...
Author : James Alan Shapiro
Publisher : Pearson Education
Page : 273 pages
File Size : 14,6 MB
Release : 2011
Category : Juvenile Nonfiction
ISBN : 0132780933
This book proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents an alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and saltationism, and points toward an emerging synthesis of physical, information, and biological sciences.
Author : Heinz Saedler
Publisher : Springer Science & Business Media
Page : 242 pages
File Size : 41,61 MB
Release : 2012-12-06
Category : Science
ISBN : 3642797954
Most genes are lined up on chromosomes like pearls on a string. However, a certain class of genes differ by being highly mobile; and the mecha they are termed transposons. Their properties of transposition will be described in this book. nism is the rule, irregularities like a spot on a Where uniformity plain-coloured surface strike the eye. Thus the phenomenon of has long been a source of fascina variegation among organisms In plants, variegation is most easily recognised as irregulari tion. in pigment patterns on leaves, flowers and seeds, but other ties as leaf or flower form might also show characteristics such In 1588, such a variegation pattern was described in variegation. kernels of Zea mays by Jacob Theodor of Bergzabern, a village is so detailed that if south of Strasbourg. The report by Theodor one counts the different kernel phenotypes described it be is looking at a Mendelian segrega comes clear that the author had tion. It goes without saying that Latin-American Indians already bred such variegated material much earlier, but no descriptions have yet been uncovered. Meanwhile, genetically heritable variegation patterns have been described at many different loci in more than 34 different plant species.
Author : Renato Paro
Publisher : Springer Nature
Page : 215 pages
File Size : 26,56 MB
Release : 2021-03-23
Category : Science
ISBN : 3030686701
This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Author : Pierre Capy
Publisher : Springer Science & Business Media
Page : 366 pages
File Size : 32,33 MB
Release : 1998-01-31
Category : Science
ISBN : 9780792346906
During the last 50 years, the perception oftransposable elements (TEs) has changed considerably from selfish DNA to sequences that may contribute significantly to genome function and evolution. The recent increased interest in TEs is based on the realization that they are a major genetic component (at least 10--20%) of all organisms and a major contributor to the mutation process. It is currently estimated that 70--80% of spontaneous mutations are the result of TE-mediated insertions, deletions, or chromosomal rearrangements. Thus, it seems at least plausible that TEs may playa significant role in the adaptation and evolution of natural populations and species. The ubiquity of TEs suggests that they are an old component of genomes which have been vertically transmitted through generations over evolutionary time. However, detailed analyses carried out over the last 20 years have revealed several unusual features of TE evolution: (i) TEs can be horizontally transferred between species; (ii) TE evolutionary rates can be dramatically increased by specific inactivation processes, such as the RIP (Repeat Induced Point mutation) mechanism in fungi; (iii) TEs can influence the regulation of other TEs by insertion or deletion; (iv) different classes of TEs in even distantly related species can be remarkably similar in both structure and function.
