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Genetic Susceptibility to Infectious Diseases

Author : Richard A. Kaslow M.D.

Publisher : Oxford University Press

Page : 464 pages

File Size : 35,18 MB

Release : 2008-03-03

Category : Medical

ISBN : 019972122X

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Book Description

Infectious diseases are commonly regarded as a distinct category, with different causes and patterns than chronic or genetic disease. But in fact there are many varieties of genetic susceptibility to infection, the subject of this book, which will be divided into three sections: 1) concepts and methods, 2) genes and pathophysiologic mechanisms, and 3) infectious agents and diseases. No currently plubished text on either genetics or infectious diseases focuses on the genetic aspects of the special relationship between host and pathogen in the way envisioned for Section 1. No other work on the selected genes regulating immunity deals as systematically with the sequence variation/function relationships most pertinent to infection as planned for Section 2. And no other book gives as meaningful a picture of how these genes operate in infectious disease as Section 3 will.



Genetics and Evolution of Infectious Diseases

Author : Michel Tibayrenc

Publisher : Elsevier

Page : 1002 pages

File Size : 44,60 MB

Release : 2024-07-19

Category : Medical

ISBN : 0443288194

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Book Description

Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. - Takes an integrated approach to infectious diseases - Provides the latest developments in the field of infectious diseases - Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases - Includes updated and revised contributions from leading authorities, along with six new chapters



Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes

Publisher : World Bank Publications

Page : 1027 pages

File Size : 45,5 MB

Release : 2017-11-06

Category : Medical

ISBN : 1464805253

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Book Description

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.



The Genetics of African Populations in Health and Disease

Author : Muntaser E. Ibrahim

Publisher : Cambridge University Press

Page : 351 pages

File Size : 31,53 MB

Release : 2019-12-19

Category : History

ISBN : 1107072026

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Book Description

A pioneering work that focuses on the unique diversity of African genetics, offering insights into human biology and genetic approaches.



Immunodeficient Rodents

Author : Institute of Laboratory Animal Resour

Publisher : Legare Street Press

Page : 0 pages

File Size : 49,72 MB

Release : 2023-07-18

Category :

ISBN : 9781019453094

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Book Description

This informative guide provides a comprehensive overview of the biology and care of immunodeficient rodents, which are essential for the study of human diseases and the development of new treatments. It is an invaluable resource for scientists, veterinarians, and animal care professionals. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.



Vaccine Safety Forum

Author : Institute of Medicine

Publisher : National Academies Press

Page : 71 pages

File Size : 22,49 MB

Release : 1997-08-10

Category : Medical

ISBN : 0309057914

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Book Description

On November 6, 1995, the Institute of Medicine's Vaccine Safety Forum convened a workshop on detecting and responding to adverse events following vaccination. Workshop speakers and participants discussed the difficulties in detecting adverse events, current adverse events detection and response methods and procedures, suggestions for improving the means of detecting and responding to adverse events following vaccination, and future areas of research. This document represents a summary of that workshop.



Genome-Wide Association Studies

Author : Tatsuhiko Tsunoda

Publisher : Springer Nature

Page : 216 pages

File Size : 21,52 MB

Release : 2019-10-31

Category : Medical

ISBN : 9811381771

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Book Description

This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and disease diversity. In Genome-Wide Association Studies, experts in the field explore in depth the impacts of GWAS on genomic research into a variety of common diseases, including cardiovascular, autoimmune, diabetic, cancer, and infectious diseases. The book will equip readers with a sound understanding both of the types of disease and phenotypes that are suited for GWAS and of the ways in which a road map resulting from GWAS can lead to the realization of personalized/precision medicine: functional analysis, drug seeds, pathway analysis, disease mechanism, risk prediction, and diagnosis.



Genetic Predisposition to Disease

Author : Sara L. Torres

Publisher :

Page : 322 pages

File Size : 40,35 MB

Release : 2008

Category : Disease susceptibility

ISBN :

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Book Description

A genetic predisposition is a genetic effect which influences the phenotype of an organism but which can be modified by the environmental conditions. Genetic testing is able to identify individuals who are genetically predisposed to certain health problems such as cancer or other life altering diseases. This book discusses the determination of the genetic basis of health problems that will help the precise mechanisms of health problem such as a disease or physical disorder.



Assessing Genetic Risks

Author : Institute of Medicine

Publisher : National Academies Press

Page : 353 pages

File Size : 28,89 MB

Release : 1994-01-01

Category : Medical

ISBN : 0309047986

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Book Description

Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.



Opportunistic Infections

Author : David S. Lindsay

Publisher : Springer Science & Business Media

Page : 249 pages

File Size : 10,95 MB

Release : 2008-04-16

Category : Medical

ISBN : 1402078463

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Book Description

Opportunistic Infections: Toxoplasma, Sarcocystis, and Microsporidia will focus on two important Genera of Apicomplexan parasites, Toxoplasma gondii and Sarcocystis species, and the medically important members of the Phylum Microsporida. We have been fortunate in obtaining excellent contributions from many experts in the field. Volumes in the "World Class Parasites" book series are written for researchers, students and scholars who enjoy reading about excellent research on problems of global significance. Each volume focuses on a parasite, or group of parasites, that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. The volumes are intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. They integrate vector, pathogen and host biology and celebrate the diversity of approach that comprises modern parasitological research.