Genetics and Dental Health


Book Description




Genetic Basis of Oral Health Conditions


Book Description

This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing. Dental professionals now need to understand why one person is susceptible to a particular oral health condition while a first-degree relative either does not develop the condition or does so in a less severe form. Knowledge of how genes operate in the susceptible host is essential if patients are to be offered accurate advice about their risks. The information provided in this book will assist in the delivery of effective personalized dental care through optimization of preventive strategies. It will enable the practitioner to explain the extent to which a patient’s condition is pure "bad luck", whether that bad luck can be changed by behavioral choices, and how many of our behaviors are influenced by genes.




Genetic Basis of Oral Health Conditions


Book Description

This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing. Dental professionals now need to understand why one person is susceptible to a particular oral health condition while a first-degree relative either does not develop the condition or does so in a less severe form. Knowledge of how genes operate in the susceptible host is essential if patients are to be offered accurate advice about their risks. The information provided in this book will assist in the delivery of effective personalized dental care through optimization of preventive strategies. It will enable the practitioner to explain the extent to which a patient’s condition is pure "bad luck", whether that bad luck can be changed by behavioral choices, and how many of our behaviors are influenced by genes.




Genetics and Oral Health


Book Description

Genetics and Oral health is a comprehensive yet brief review on the vast subject of Genetics.It gives a fresh and clear perspective of various genetic factors and their influence on oral health. This book introduces readers to the topic, includes various principles and terminologies used in Genetics, and classifies different types of genetic disorders in detail.Also, common oral disorders like Dental caries, Periodontal diseases, Malocclusions, Enamel and dentine anomalies, Syndromology and malformations, Cleft lip and palate, Head and Neck cancer, Wound healing and its associated genetics is exhaustively covered in the book with the help of many pictures and illustrations for easy understanding of the reader




Genetics and oral health


Book Description

This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing.




The Overlooked Individual: Susceptibility to Dental Caries, Erosive Tooth Wear and Amelogenesis


Book Description

Individual susceptibility to disease (i.e., one's own genetic background) is one of the three main components classically described in the etiology of dental caries. Hence, genes influence susceptibility to erosive tooth wear, dental development, and response to treatments and interventions. This publication is an up-to-date overview of individual susceptibility to dental caries, erosive tooth wear, and disturbances of dental development from different clinically relevant perspectives. One of the most recognized scientists in this field reports on recent research relating to human genetics - from general summaries to recommendations for daily clinical work and population-level interventions. This book covers all aspects of individual susceptibility to dental caries and erosive tooth wear. Several chapters deal with potential biological mechanisms, with additional ones providing a strong foundation in human genetics, and other chapters touch on efficacy of therapies and alternative concepts. This book is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on dental caries and erosive tooth wear.




Genetics of Dental Caries


Book Description

Oftentimes dentists have patients who continuously have issues with dental caries. These patients follow the advice of dentists by properly brushing and flossing their teeth, as well as adjusting their diets to aid in the maintenance of their teeth. However, these precautions patients adhere to are not universally successful; many still find themselves susceptible to frequent dental caries. Therefore, it is important to understand the genetic underpinnings to explain why some are more prone to dental caries than others. This knowledge can further be applied in researching targeted gene therapies to prevent dental caries formation, while simultaneously altering the standard treatment plan. There has been promising therapeutic research to select genes for strong enamel growth and healthy saliva, as well as genes that attack and prevent bacteria in the mouth. The usage of gene therapy is subject to controversy in Jewish law. However, these specific therapies should escape this controversy, as there is a health motivation for its allowance. Both Judaism and science mutually agree that maintaining proper oral care is crucial to the health of the mouth.




Twin Studies:


Book Description

This volume is about an ongoing long-term research initiative led by researchers from the School of Dentistry at the University of Adelaide. The aim of this book is to provide an overview of the studies of the teeth and faces of Australian twins and their families that have extended over more than thirty years.







Oral Health Epidemiology


Book Description

As a result of scientific advancements and changing demographics in the United States and around the world, people of all ethnic groups and nationalities are retaining their teeth longer. Todays oral health professionals must therefore be prepared to make educated and scientifically-reasoned choices addressing a wide range of oral diseases for patients of all ages, and for ambulatory as well as non-ambulatory patients across all demographic profiles. As the first text of its kind, Oral Health Epidemiology: Principles and Practice explores the full spectrum of epidemiological and translational clinical research including fundamental mechanisms of human disease, therapeutic intervention, clinical trials, and oral epidemiology. Topics that are unique to oral health, such as the frequent use of split-mouth design on oral research, crossover techniques and clustered nature of caries, periodontal and other dental disease data, are all thoroughly addressed. Key Features: Thoroughly explores clinicaltranslational research and the special needs of oral health study designs that are applicable across all specialties in dentistry. Serves as a basic guide to advanced techniques such as bioinformatics, genetics, molecular biology, and computer simulation, biostatistics that are now used regularly in oral health research. Prepares the reader to design studies, translate the findings to practice, and conduct logical critique of scientific literature.