Self-Assembled Bio-Nanomaterials


Book Description

Biomolecular self-assembly provides a green, facile, and highly effective method to synthesize various functional nanomaterials that have exhibited considerable potential in the fields of nanotechnology, materials science, biomedicine, tissue engineering, food science, energy storage, and environmental science. In this collection of articles, we presented recent advance in the synthesis, characterization, and applications of self-assembled bio-nanomaterials. In a comprehensive review article, the controlled self-assembly of biomolecules including DNA, protein, peptide, enzymes, virus, and biopolymers via internal interactions and external simulations is introduced and discussed in detail. In other research articles, the self-assembly of DNA, protein, peptide, bio-drugs, liquid crystal polycarbonates, and diblock copolymers to various biomimetic/bioinspired nanomaterials and their potential applications in nanopatterning, sensors/biosensors, drug delivery, anti-parasite, and water purification are demonstrated.




Functional Bionanomaterials


Book Description

This book focuses on the application of nanotechnology in medicine and drug delivery, including diagnosis and therapy. Nanomedicine can contribute to the development of a personalized medicine both for diagnosis and therapy. By interacting with biological molecules at nanoscale level, nanotechnology opens up an immense field of research and applications. Interactions between artificial molecular assemblies or nanodevices and biomolecules can be understood both in the extracellular medium and inside human cells. Operating at nanoscale allows exploitation of physical properties different from those observed at microscale, such as the volume to surface area ratio. A number of clinical applications of nanobiotechnology, such as disease diagnosis, target-specific drug delivery, and molecular imaging are being investigated. Some promising new products are also undergoing clinical trials. Such advanced applications of this approach to biological systems will undoubtedly transform the foundations of diagnosis, treatment, and prevention of disease in the future. Nanomedicine sales reached $16 billion in 2015, with a minimum of $3.8 billion in nanotechnology R&D being invested each year. Global funding for emerging nanotechnology increased by 45% per year in recent years, with product sales exceeding $1 trillion in 2013. As the nanomedicine industry continues to grow, it is expected to have a significant impact on the global economy. This book provides clear, colorful and simple illustrations, tables, and case studies to clearly convey the content to a general audience and reader. This book also discusses the development of nanobiomaterials from biogenic (biological sources) systems for healthcare and disease therapies. This book, therefore, is useful for researchers and academicians in the fields of nanotechnology, medicine, nano-biotechnology and pharmacology.




Topology in Molecular Biology


Book Description

Providing a course of modern topology intended for biologists and physicists, this book presents a class of results in molecular biology for which topological methods and ideas are important. These include: the large-scale conformation properties of DNA; computational methods; the structure of proteins; and other problems in molecular biology.




Biological and Bio-inspired Nanomaterials


Book Description

This book summarizes naturally occurring and designed bio-inspired molecular building blocks assembled into nanoscale structures. It covers a fascinating array of biomimetic and bioinspired materials, including inorganic nanozymes, structures formed by DNA origami, a wide range of peptide and protein-based nanomaterials, as well as their applications in diagnostics and therapeutics. The book elucidates the mechanism of assembly of these materials and characterisation of their mechanical and physico-chemical properties which inspires readers not only to exploit the potential applications of nanomaterials, but also to understand their potential risks and benefits. It will be of interest to a broad audience of students and researchers spanning the disciplines of biology, chemistry, engineering, materials science, and physics.




Self-Assembled Bio-Nanomaterials: Synthesis, Characterization, and Applications


Book Description

Biomolecular self-assembly provides a green, facile, and highly effective method to synthesize various functional nanomaterials that have exhibited considerable potential in the fields of nanotechnology, materials science, biomedicine, tissue engineering, food science, energy storage, and environmental science. In this collection of articles, we presented recent advance in the synthesis, characterization, and applications of self-assembled bio-nanomaterials. In a comprehensive review article, the controlled self-assembly of biomolecules including DNA, protein, peptide, enzymes, virus, and biopolymers via internal interactions and external simulations is introduced and discussed in detail. In other research articles, the self-assembly of DNA, protein, peptide, bio-drugs, liquid crystal polycarbonates, and diblock copolymers to various biomimetic/bioinspired nanomaterials and their potential applications in nanopatterning, sensors/biosensors, drug delivery, anti-parasite, and water purification are demonstrated.







Functional Nanomaterials


Book Description




Molecular Modeling and Simulation


Book Description

Very broad overview of the field intended for an interdisciplinary audience; Lively discussion of current challenges written in a colloquial style; Author is a rising star in this discipline; Suitably accessible for beginners and suitably rigorous for experts; Features extensive four-color illustrations; Appendices featuring homework assignments and reading lists complement the material in the main text




DNA Nanoscience


Book Description

DNA Nanoscience: From Prebiotic Origins to Emerging Nanotechnology melds two tales of DNA. One is a look at the first 35 years of DNA nanotechnology to better appreciate what lies ahead in this emerging field. The other story looks back 4 billion years to the possible origins of DNA which are shrouded in mystery. The book is divided into three parts comprised of 15 chapters and two Brief Interludes. Part I includes subjects underpinning the book such as a primer on DNA, the broader discipline of nanoscience, and experimental tools used by the principals in the narrative. Part II examines the field of structural DNA nanotechnology, founded by biochemist/crystallographer Nadrian Seeman, that uses DNA as a construction material for nanoscale structures and devices, rather than as a genetic material. Part III looks at the work of physicists Noel Clark and Tommaso Bellini who found that short DNA (nanoDNA) forms liquid crystals that act as a structural gatekeeper, orchestrating a series of self-assembly processes using nanoDNA. This led to an explanation of the polymeric structure of DNA and of how life may have emerged from the prebiotic clutter.