Author : Gary S. Silverman
Publisher : CRC Press
Page : 740 pages
File Size : 39,2 MB
Release : 1996-04-25
Category : Science
ISBN : 9780824795450
This handbook provides the theoretical and practical information necessary to explore new applications for Grignard reagents on a day-to-day basis, presenting a comprehensive overview of current research activities in Grignard chemistry. This book surveys specific reactions and applications of Grignard reagents, organized by type of substrate and the general category of reaction. It also summarizes the spectrum of reactions exhibited by Grignard reagents.
Author : H. G. Richey
Publisher : John Wiley & Sons
Page : 450 pages
File Size : 48,88 MB
Release : 2000
Category : Science
ISBN :
The Grignard reagent is one of the most useful and versatile reagents known to the organic chemist and 100 years after its discovery, this book presents authoritative perspectives on the significant developments taking place using Grignard Reagents and related organomagnesium compounds. This volume focuses on a dozen areas of organomagnesium chemistry, including: * New reactions of Grignard Reagents * Stereoselective Reactions of Organomagnesium Compounds * Mechanistic Features of Organomagnesium Compounds * Industrial Applications and Strategy * Unusual Organomagnesium Compounds * Structures of Organomagnesium Solids and Solutions The book will prove of great interest to academic and industrial chemists active in organometallic chemistry of main group metals, organic syntheses, reaction mechanisms and structural organic chemistry.
Author : Janine Cossy
Publisher : Walter de Gruyter GmbH & Co KG
Page : 298 pages
File Size : 45,64 MB
Release : 2016-04-25
Category : Science
ISBN : 3110352729
In 1912, the Chemistry Nobel Prize was awarded for the discovery of the so-called Grignard reagents. Nowadays, many transition metal variants are developed to modify reactivity and selectivity of the C–C bond formation reaction. The Grignard reaction is one of the fundamental organometallic reactions, often used in alcohol syntheses. With transition metals like iron, cobalt and nickel or with noble metals like copper, silver and palladium, modern Grignard reagents can be designed in reactivity, selectivity and functional group tolerance. This book, written by international experts, presents an overview on timely Grignard chemistry involving transition metals.
Author : A. Varvoglis
Publisher : Academic Press
Page : 245 pages
File Size : 43,23 MB
Release : 1996-11-14
Category : Science
ISBN : 0080534368
This book describes the fascinating chemistry of the many kinds of organic compounds of hypervalent iodine. Each chapter deals with a particular iodine compound or families of compounds which have been used as reagents in a plethora of useful transformations. These include assorted oxidation, such as with the precious Dess-Martin reagent as well as with a wide range of further reactions. Prominent features of hypervalent iodine reagents derived from iodobenzene are: ready availability, operational simplicity, mild reaction conditions, and high efficiency. They are environmentally safe and can be recycled. New species may be easily prepared by introducing substituents in the benzene ring or changing the ligand attached to iodine. Their combination with other reagents broadens considerably their synthetic potential. Today, no synthetic chemist can afford to ignore the valuable hypervalentiodine reagents. - Features up-to-date coverage of a wide range of topics - Includes many tables featuring a diversity of reactivity, and a comprehensive index - Acts as a comprehensive, up-to-date reference on all aspects of hypervalent iodine chemistry - Contains a section on unusual efficiency of hypervalent iodine reactions
Author : American Chemical Society. Division of Industrial and Engineering Chemistry
Publisher :
Page : 392 pages
File Size : 16,16 MB
Release : 1959
Category : Science
ISBN :
Author : Robert J. Ouellette
Publisher : Academic Press
Page : 498 pages
File Size : 46,80 MB
Release : 2015-02-13
Category : Science
ISBN : 0128026340
Class-tested and thoughtfully designed for student engagement, Principles of Organic Chemistry provides the tools and foundations needed by students in a short course or one-semester class on the subject. This book does not dilute the material or rely on rote memorization. Rather, it focuses on the underlying principles in order to make accessible the science that underpins so much of our day-to-day lives, as well as present further study and practice in medical and scientific fields. This book provides context and structure for learning the fundamental principles of organic chemistry, enabling the reader to proceed from simple to complex examples in a systematic and logical way. Utilizing clear and consistently colored figures, Principles of Organic Chemistry begins by exploring the step-by-step processes (or mechanisms) by which reactions occur to create molecular structures. It then describes some of the many ways these reactions make new compounds, examined by functional groups and corresponding common reaction mechanisms. Throughout, this book includes biochemical and pharmaceutical examples with varying degrees of difficulty, with worked answers and without, as well as advanced topics in later chapters for optional coverage. Incorporates valuable and engaging applications of the content to biological and industrial uses Includes a wealth of useful figures and problems to support reader comprehension and study Provides a high quality chapter on stereochemistry as well as advanced topics such as synthetic polymers and spectroscopy for class customization
Author : Stéphane Caron
Publisher : John Wiley & Sons
Page : 850 pages
File Size : 18,19 MB
Release : 2020-02-05
Category : Science
ISBN : 1119448859
This book is a hands-on guide for the organic chemist. Focusing on the most reliable and useful reactions, the chapter authors provide the information necessary for a chemist to strategically plan a synthesis, as well as repeat the procedures in the laboratory. Consolidates all the key advances/concepts in one book, covering the most important reactions in organic chemistry, including substitutions, additions, eliminations, rearrangements, oxidations, reductions Highlights the most important reactions, addressing basic principles, advantages/disadvantages of the methodology, mechanism, and techniques for achieving laboratory success Features new content on recent advances in CH activation, photoredox and electrochemistry, continuous chemistry, and application of biocatalysis in synthesis Revamps chapters to include new and additional examples of chemistry that have been demonstrated at a practical scale
Author : Lutz Ackermann
Publisher : John Wiley & Sons
Page : 561 pages
File Size : 19,10 MB
Release : 2009-04-22
Category : Science
ISBN : 3527627332
Today, arylation methods are belonging to the most important reaction types in organic synthesis. Lutz Ackermann, a young and ambitious professor has gathered a number of top international authors to present the first comprehensive book on the topic. Starting from a historical review, the book covers hot topics like Palladium-catalyzed arylation of N-H and alpha-C-H-acidic Bonds, Copper-catalyzed arylation of N-H and O-H Bonds, direct arylation reactions, carbanion aromatic synthesis, arylation reactions of alkenes, alkynes and much more. This compact source of high quality information is indispensable to synthetic chemists and those working in the pharmaceutical and chemical industry.
Author : Basil J. Wakefield
Publisher : Academic Press
Page : 269 pages
File Size : 22,22 MB
Release : 1995-03-16
Category : Science
ISBN : 0080538177
The book opens with a general overview of the constitution and reactivity of organomagnesium compounds, followed by information on handling them and on their detection and estimation. Throughout, practical aspects aswell as principles are emphasized. The chapters on the synthesis of organomagnesium compounds cover the preparation of special forms of metallic magnesium and the reaction of magnesium with substrates such as dienes, as well as the traditional preparation of Grignard reagents. Preparations by metallation and metal-halogen exchanges are also included, as are newer methods such as hydromagnesiation of alkenes and alkynes. Systematic coverage is provided on synthetically useful reactions of organomagnesium compounds. Of fundamental importance in organic synthesis are carbon-carbon bond forming reactions; additions to carbon-carbon, carbon-nitrogen, carbon-oxygen, and carbon-sulfur multiple bonds; and nucleophilic substitution at carbon. The formation of carbon-heteroatom bonds in organic compounds is described, where the heteroatom is hydrogen, nitrogen, oxygen, sulfur, or halogen. Finally, the use of organomagnesium compounds in preparing other organometalloid and organometallic compounds is outlined. Representative experimental procedures are included throughout the book, and tables with references to well-described examples are provided. - Presents a general overview of the constitution and reactivity of organomagnesium compounds - Provides coverage on the detection and estimation of organomagnesium compounds - Emphasizes practical aspects as well as principles - Covers the preparation of special forms of metallic magnesium and the reaction of magnesium with substrates such as dienes - Includes preparations by metallation and metal-halogen exchanges - Reviews new preparation methods such as hydromagnesiation of alkenes and alkynes - Outlines information on synthetically useful reactions of organomagnesium compounds - Describes the formation of carbon-heteroatom bonds in organic compounds - Addresses the use of organomagnesium compounds in preparing other organometalloid and organometallic compounds - Includes representative procedures and tables with references to well-described examples
Author : Raj K. Bansal
Publisher : Jones & Bartlett Learning
Page : 436 pages
File Size : 22,77 MB
Release : 1996
Category : Science
ISBN : 9780763706654
Designed for undergraduate and beginning graduate courses in organic synthesis.
