Holland-Frei Cancer Medicine


Book Description

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates




Cooperation of Liver Cells in Health and Disease


Book Description

It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.







Fibroblast Growth Factors


Book Description

Fibroblast Growth Factors presents research and results from the leading global research group on FGF, providing up-to-date and comprehensive coverage of the field. The book describes the history, basic research and growth engineering technology involved with FGFs, while also introducing detailed research methods. It comprises eight chapters that detail successes and problems in relation to wound healing of engineered growth factors and considers injury repair and regeneration, non-mitogenic mutants, structure modification, pathology, physiology, pharmacology, development, FGF/FGFR inhibitors, bioengineering, and new drug development. It will serve as a key reference book for researchers working on FGFs. - Focuses on the growth engineering aspects of FGF-based drug development and its clinical applications - Presents useful information on the history of FGFs, along with basic research and growth engineering technology - Provides detailed, practical research methods and results obtained on FGFs - Considers the successes and problems in engineering technology - Offers up-to-date, comprehensive coverage from the world's leading research group




Engineering Strategies for Regenerative Medicine


Book Description

Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine. Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development. - Considers how engineering strategies can accelerate novel advances in regenerative medicine - Takes an interdisciplinary approach, integrating different aspects of research, technology and application - Provides up-to-date coverage on this rapidly developing area of medicine - Presents insights from an experienced and cross-disciplinary group of researchers and practitioners with close links to industry







Basic Neurochemistry


Book Description

Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.




Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy


Book Description

Annotation G.V. Sherbet provides insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. The book focuses on the relationships and convergence of growth factors and their receptors in development and pathogenesis.




Plant Growth and Development


Book Description

This book provides current information on synthesis of plant hormones, how their concentrations are regulated, and how they modulate various plant processes. It details how plants sense and tolerate such factors as drought, salinity, and cold temperature, factors that limit plant productivity on earth. It also explains how plants sense two other environmental signals, light and gravity, and modify their developmental patterns in response to those signals. This book takes the reader from basic concepts to the most up-to-date thinking on these topics. * Provides clear synthesis and review of hormonal and environmental regulation of plant growth and development * Contains more than 600 illustrations supplementary information on techniques and/or related topics of interest * Single-authored text provides uniformity of presentation and integration of the subject matter * References listed alphabetically in each section




Disease Control Priorities, Third Edition (Volume 8)


Book Description

More children born today will survive to adulthood than at any time in history. It is now time to emphasize health and development in middle childhood and adolescence--developmental phases that are critical to health in adulthood and the next generation. Child and Adolescent Health and Development explores the benefits that accrue from sustained and targeted interventions across the first two decades of life. The volume outlines the investment case for effective, costed, and scalable interventions for low-resource settings, emphasizing the cross-sectoral role of education. This evidence base can guide policy makers in prioritizing actions to promote survival, health, cognition, and physical growth throughout childhood and adolescence.