Diagnostic Electron Microscopy


Book Description

Diagnostic Electron Microscopy Diagnostic Electron Microscopy: A Practical Guide to Interpretation and Technique summarises the current interpretational applications of TEM in diagnostic pathology. This concise and accessible volume provides a working guide to the main, or most useful, applications of the technique including practical topics of concern to laboratory scientists, brief guides to traditional tissue and microbiological preparation techniques, microwave processing, digital imaging and measurement uncertainty. The text features both a screening and interpretational guide for TEM diagnostic applications and current TEM diagnostic tissue preparation methods pertinent to all clinical electron microscope units worldwide. Containing high-quality representative images, this up-to-date text includes detailed information on the most important diagnostic applications of transmission electron microscopy as well as instructions for specific tissues and current basic preparative techniques. The book is relevant to trainee pathologists and practising pathologists who are expected to understand and evaluate/screen tissues by TEM. In addition, technical and scientific staff involved in tissue preparation and diagnostic tissue evaluation/screening by TEM will find this text useful.




Manual of Surgical Pathology


Book Description

Practical guide to the complete evaluation of the surgical pathology specimen. Provides instructions on dissecting, staining, and processing and includes a concise listing of common histochemical stains, their staining patterns, and their common uses.




Diagnostic Pathology: Bone


Book Description

Diagnostic Pathology: Bone was designed for practicing pathologists who need access to up-to-date, comprehensive, and concise bone pathology knowledge in one convenient place. It includes the latest diagnostic information in this challenging subspecialty, while its unique image collection serves as an exceptional educational aid. Authored and updated by experts in the field, Diagnostic Pathology: Bone will be an essential guide to understanding bone tumor pathology and diagnosis. Features quick-reference test data tables and diagnoses of various bone and cartilage tumor types Templated page layout, bulleted text, and a generous number of high-quality images for point-of-care clinical reference Stunning image collection includes gross pathology, histopathology, immunohistochemistry, FISH, and correlative radiologic imaging to serve as an exceptional educational aid Brand-new chapters covering Ewing-like sarcomas with specific translocations, other types of vascular tumors of bone (new entities), and tumors of the synovium Includes new molecular pathology diagnostic information for bone tumors and new immunohistochemical antigens to identify bone pathologies




Canine and Feline Cytology - E-Book


Book Description

Master the art and science of specimen collection, preparation, and evaluation with Canine & Feline Cytology: A Color Atlas and Interpretation Guide, Second Edition. This easy-to-use guide covers all body systems and fluids including a special chapter on acquisition and management of cytology specimens. Hundreds of vivid color images of normal tissue alongside abnormal tissue images – plus concise summaries of individual lesions and guidelines for interpretation - will enhance your ability to confidently face any diagnostic challenge. A greatly expanded image collection, with more than 1,200 vivid, full-color photomicrographic illustrations depicting multiple variations of normal and abnormal tissue for fast and accurate diagnosis Clear, concise descriptions of tissue sampling techniques, slide preparation and examination guidelines Helpful hints for avoiding technical pitfalls and improving diagnostic quality of specimens Includes all body systems and fluids as well as pathological changes associated with infectious agents Histologic and histopathologic correlates provided in all organ system chapters. User-friendly format and logical organization facilitates readability and learning. Expert contributors represent the most respected leaders in the field. NEW! Chapter on Fecal Cytology Highlighted boxes featuring Key Points provide helpful tips for best conceptual understanding and diagnostic effectiveness Photomicrographs now include more comparative histology Discussions of broader uses of stains and immunocytochemistry for differential cytologic characterization Expanded chapter on Advanced Diagnostic Techniques includes more methodology and application of current tools, representing advances in both aspiration and exfoliative cytology.




Microwave Techniques and Protocols


Book Description

Richard Giberson and Richard Demaree, Jr, have collected a wide range of time-saving microwave techniques for processing biological samples for evaluation by many different microscopic methods. Described in step-by-step detail by hands-on researchers, these readily reproducible protocols include both optimized classic methods and such state-of-the art techniques as in vivo labeling, formalin fixation of fresh tissue, vacuum processing, and processing for scanning electron microscopy. Each stand-alone microwave method has been handcrafted by a researcher who regularly uses it to ensure processing success and the brightest quality result.




Diagnostic Atlas of Renal Pathology E-Book


Book Description

Diagnostic Atlas of Renal Pathology, by Agnes B. Fogo, MD and Michael Kashgarian, MD, delivers practical, highly visual guidance for effectively and accurately diagnosing a wide range of pathologic entities. More than 700 high-quality illustrations help you to recognize the pathologic features and clinical manifestations of both common and rare renal disorders and to formulate confident and accurate diagnoses. Thoroughly updated throughout, this companion to Brenner & Rector’s The Kidney, 9th Edition provides the newest information regarding categorizing and classification of diseases and describes how this relates to the various morphological lesions illustrated and their clinical significance. See more than 700 high quality representative images of light, immunofluorescence, and electron microscopy for each diagnostic entity with correlations to clinical presentation and pathogenesis. Easily locate in-depth information on any disease's clinical course and treatment by cross-referring companion text, Brenner & Rector’s The Kidney. Grasp key characteristic pathologic findings and prognostic, pathogenetic, and etiologic information through focused, detailed discussions. Make accurate, complete reports by fully understanding clinical correlations. Get an in-depth examination of pathophysiology, clinical presentations, and comprehensive references Keep current with the latest knowledge and evidence-based practices. Comprehensive updates throughout include a brand-new chapter on "Approaches to Chronic Kidney Disease" that includes coverage of Chronic Kidney Disease; Age-Related Sclerosis; Glomerular vs. Tubulointerstitial vs. Vascular Disease; and the differential diagnostic approach to Segmental Glomerulosclerosis lesions. Extensive updates to all previous chapters include new classifications of various diseases such as igA nephropathy, diabetic nephropathy, crescentic GN, and renal transplant rejection. Stay well informed about hot topics including acute phosphate nephropathy; new concepts in the pathogenesis of thrombotic microangiopathies and eclampsia; and new information relative to etiology and pathogenesis of podocytopathies. Quickly access the information you need thanks to a user-friendly format, tables and sidebars with key points and differential diagnoses, and chapters that include concise, templated discussions regarding the etiology and pathogenesis of the disorder.




Whole Slide Imaging


Book Description

This book provides up-to-date and practical knowledge in all aspects of whole slide imaging (WSI) by experts in the field. This includes a historical perspective on the evolution of this technology, technical aspects of making a great whole slide image, the various applications of whole slide imaging and future applications using WSI for computer-aided diagnosis The goal is to provide practical knowledge and address knowledge gaps in this emerging field. This book is unique because it addresses an emerging area in pathology for which currently there is only limited information about the practical aspects of deploying this technology. For example, there are no established selection criteria for choosing new scanners and a knowledge base with the key information. The authors of the various chapters have years of real-world experience in selecting and implementing WSI solutions in various aspects of pathology practice. This text also discusses practical tips and pearls to address the selection of a WSI vendor, technology details, implementing this technology and provide an overview of its everyday uses in all areas of pathology. Chapters include important information on how to integrate digital slides with laboratory information system and how to streamline the “digital workflow” with the intent of saving time, saving money, reducing errors, improving efficiency and accuracy, and ultimately benefiting patient outcomes. Whole Slide Imaging: Current Applications and Future Directions is designed to present a comprehensive and state-of the-art approach to WSI within the broad area of digital pathology. It aims to give the readers a look at WSI with a deeper lens and also envision the future of pathology imaging as it pertains to WSI and associated digital innovations.




Essentials of Anatomic Pathology


Book Description

In the 8 years since the publication of the first edition of Essentials of Anatomic Pathology, great strides have been made in our understanding of diseases and neoplastic processes. Many clinically important new histopathologic entities have been described or more fully defined in virtually every organ. Numerous clinically important diagnostic and prognostic markers have entered routine practice. Genetic testing for the early detection of cancers and the molecular classification of diseases has become increasingly important. This is an age of enlightenment in surgical pathology, and the authors of this new volume have captured this sense of excitement herein. This much praised and widely used reference manual on has been extensively revised and expanded to cover the entire field of anatomic pathology. The Third Edition features the incorporation of full-color images in the text with updates of new diagnostic and prognostic information. New classifications and numerous new entities and histologic variants are fully explored. Useful immunostaining biomarkers and emerging molecular targets and relevant molecular findings that have emerged from recent genomic studies are incorporated in each chapter. Written by internationally recognized authorities, the comprehensive, evidence-based practice information is presented in an outline format that is clear and easy to follow. Up-to-date and richly detailed, Essentials of Anatomic Pathology, Third Edition offers both the pathologist-in-training and the practicing pathologist a concise summary of all the critical information needed to recognize, understand and interpret anatomic pathology.




The Science of Laboratory Diagnosis


Book Description

This fully revised and updated edition of The Science of Laboratory Diagnosis provides a concise description of all common laboratory tests available in medical practice with notes on their application, the accuracy of each test, the historical background to the adoption of various tests and their effectiveness in diagnosis. Well illustrated, with clear headings, tables, flow charts and pathology slides, most in full colour Provides an accessible reference book in which relevant information can be found easily Page design facilitates rapid assimilation of principles and key facts All the chapters have been updated and new material has been introduced to cover recently developed techniques, such as fluid-based cytology, telepathology and proteomics The Science of Laboratory Diagnosis, Second Edition is an essential primary reference source for everyone working in a clinical laboratory. This book is essential reading for pathologists, biomedical scientists, medical laboratory scientific officers and all clinicians involved in laboratory research. Reviews of the First Edition: "The text is concise, wide-ranging and easy to digest. The ease of extraction of the important facts make it an ideal source of information for use in a variety of situations from the postgraduate examination to the clinical directors' board meeting." BULLETIN OF THE ROYAL COLLEGE OF PATHOLOGISTS "The editors have done a marvellous job, more than fulfilling their stated aim of producing a volume describing the multidisciplinary state of modern pathology which will be of interest to a wide range of readers. ... I was particularly impressed by the many tables and flow charts, which can be used as aids to decision making." JOURNAL OF CLINICAL PATHOLOGY "This is an excellent book to dip into and get a feel for techniques used in the other disciplines of pathology." ANNALS OF CLINICAL BIOCHEMISTRY