Handbook of Polyester Drug Delivery Systems


Book Description

In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.




Handbook of Polyester Drug Delivery Systems


Book Description

In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.




Fiber and Textile Engineering in Drug Delivery Systems


Book Description

Fiber and Textile Engineering in Drug Delivery Systems explains how innovative textile processing methods including rotary spinning, microfluidics, wet spinning and electrospinning can be used to produce novel drug delivery solutions. This topical book provides detailed descriptions of how to produce such new materials for this purpose, with foundational content to help readers from a range of backgrounds understand the context of material selection and design decisions. Emphasis is given to the engineering side of the manufacturing of the textile and its role in drug delivery, but this also acts as a guide to pharmaceutical applications of textile fibers for materials scientists. Drug delivery research is rapidly expanding and experimenting with new materials to drive improved clinical outcomes as the efficacy of the therapeutic molecule is highly dependent on the right choice of carrier system. Recently, fiber based carriers at both nano and micro scales are gaining interest in the scientific community due to ease of manufacturing, high surface area to volume ratio, desirable drug release kinetics and high mechanical strength. - Describes methods for material selection and design for drug delivery systems - Provides case studies to explain how these techniques can be applied successfully - Covers the regulatory and legal aspects of the use of the textiles and fibers in drug delivery




Drugs & Pharmaceutical Technology Handbook


Book Description

Drugs and pharmaceutical industry plays a vital role in the economic development of a nation. It is one of the largest and most advanced sectors in the world, acting as a source for various drugs, medicines and their intermediates as well as other pharmaceutical formulations. India has come a long way in this field, from a country importing more than 95% of its requirement of drugs and pharmaceuticals; India now is exporting it even to developed countries. Being the intense knowledge driven industry, it offers innumerable business opportunities for the investors/ corporate the world over. The existence of well defined and strong pharmaceutical industry is important for promoting and sustaining research and developmental efforts and initiatives in an economy as well as making available the quality medicines to all at affordable prices. That is, it is essential to improve the health status of the individuals as well as the society as a whole, so that positive contributions could be made to the economic growth and regional development of a country. On the global platform, India holds fourth position in terms of volume and thirteenth position in terms of value of production in pharmaceuticals. The pharmaceutical industry has been producing bulk drugs belonging to all major therapeutic groups requiring complicated manufacturing processes as well as a wide range of pharmaceutical machinery and equipments. The modern Indian Pharmaceutical Industry is recent and its foundation was laid in the beginning of the current century. The pharmaceutical industry can be broadly categorised as bulk drugs, formulations, IV fluids and pharmaceutical aids (such as medical equipment, hospital disposables, capsules, etc.). Special feature of the pharmaceutical industry is a large number of manufacturers in the small scale sector. The government is also encouraging the SSI sector providing some incentives. The recent developments in the technology and R & D work in this field have led to the increased growth rate of industries and have established Indian Pharmaceutical industries in the international market. The content of the book includes information about properties, general methods of analysis, methods of manufacture, of different types of drugs and pharmaceuticals. Some of the fundamentals of the book are polymeric materials used in drug delivery systems , theoretical aspects of friction and lubrication , a convenient method for conversion of quinine to quinidine, formulation and evaluation of bio-available enteric-coated erythromycin and metronidazole tablets, extraction of virginiamycin, antipyretics and analgesics, column chromatographic assay of aspirin tablets, differentiating titration of phenacetin and caffeine, infrared spectra of some compounds of pharmaceutical interest etc. This book covers an intensive study on manufacturing, production, formulation and quality control of drugs and pharmaceuticals with technology involved in it. This book is an invaluable resource for technologists, professionals and those who want to venture in this field. 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Novel Drug Delivery Systems for Phytoconstituents


Book Description

Novel Drug Delivery Systems for Phytoconstituents discusses general principles of drug targeting, construction material and technological concerns of different phytoconstituent in delivery systems. It focuses on the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, route of administration, biological activity and their applications. It dicusses therapeutic activities of plant derived chemicals, their limitations in clinical applications and novel drug delivery solutions to overcome them to provide better therapeutic effects with controlled and targeted drug delivery. Focus on drug delivery of phytomolecules Act as bridge between natural product scientist and clinical doctors Discusses mechanism of poor bioavailability of herbal molecules Increases awareness towards phytochemical efficacy Summarizes efficient novel delivery systems-based formulations. It extensively covers the applications of novel drug delivery systems including polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid capsules, liposomes, phytosomes, microsphere, transferosomes, and ethosomes. Some chapters are especially focused on anticancer phytodrugs, silymarin, andrographolide, berberine, and curcumin delivery with special emphasis on their application.




Handbook of Research on Nano-Drug Delivery and Tissue Engineering


Book Description

With contributions from leading researchers in the nanomedicine field from industry, academia, and government and private research institutions across the globe, the volume provides an up-to-date report on topical issues in nano-drug delivery and nanotechnological approaches to tissue engineering. The volume offers research on a variety of diverse nano-based drug delivery systems along with discussions of their efficacy, safety, toxicology, and applications for different purposes. Focusing on nanotechnology approaches to tissue engineering, this volume considers the use of hydrogel systems, nanoceria and micro- and nano-structured biomaterials for bone tissue engineering, mesenchymal stem cells, and more.




Handbook of Polymers for Pharmaceutical Technologies, Biodegradable Polymers


Book Description

Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers




Handbook of Biodegradable Polymers


Book Description

This book presents a comprehensive and authoritative review of the recent developments and advances in biodegradable polymers and their biomedical applications. Following an interdisciplinary approach, it combines the medical and pharmaceutical fields in conjunction with biomedical engineering, polymer science, materials science, and pharmacological aspects of biodegradable polymers. The text covers the synthesis, properties, and characterization of biodegradable polymers and systems and their applications in sustained drug delivery, anticancer therapy, vaccine delivery, gene delivery, surgery, wound care, cardiology, dentistry, orthopedics, medical devices, tissue engineering, and cosmeceuticals. It also details the safety aspects, market economy, challenges, and opportunities related to biodegradable polymers, providing an understanding of the commercial and translational aspects of these crucial biomaterials. Edited and authored by renowned scientists working on biodegradable polymers, biocomposites, biodegradable systems, and implants, the book is an important resource for academicians, researchers, students, professionals, and general readers interested in exploring the potential biomedical applications of biodegradable polymers.