Health Care-Associated Transmission of Hepatitis B and C Viruses, An Issue of Clinics in Liver Disease


Book Description

This issue offers the latest information regarding the transmission of hepatitis viruses in various healthcare settings. It delves with a very timely and interesting patient safety subject that specifically targets healthcare professionals, gastroenterologists, hepatologists, oncologists, dentists and all healthcare workers to adopt and share a variety of best practices to prevent this adverse event. Well known faculty in liver disease, infection control as well as a medical practice in a legal setting have been assembled to produce a comprehensive and concise edition that highlights the latest information regarding hepatitis B and C transmission in healthcare. It aims to provide an overview on the molecular epidemiology, the outbreak reports, the transmission in hemodialysis, endoscopy, dental, oncology, management, legal aspects and the infection prevention measures to reduce the risk of needless exposure of patients to these blood borne pathogens.




Health Care-Associated Transmission of Hepatitis B and C Viruses, an Issue of Clinics in Liver Disease


Book Description

This issue offers the latest information regarding the transmission of hepatitis viruses in various healthcare settings. It delves with a very timely and interesting patient safety subject that specifically targets healthcare professionals, gastroenterologists, hepatologists, oncologists, dentists and all healthcare workers to adopt and share a variety of best practices to prevent this adverse event. Well known faculty in liver disease, infection control as well as a medical practice in a legal setting have been assembled to produce a comprehensive and concise edition that highlights the latest information regarding hepatitis B and C transmission in healthcare. It aims to provide an overview on the molecular epidemiology, the outbreak reports, the transmission in hemodialysis, endoscopy, dental, oncology, management, legal aspects and the infection prevention measures to reduce the risk of needless exposure of patients to these blood borne pathogens.




Eliminating the Public Health Problem of Hepatitis B and C in the United States


Book Description

Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.




Hepatitis and Liver Cancer


Book Description

The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.




Care of the Patient with Hepatitis C Virus Infection, An Issue of Infectious Disease Clinics


Book Description

Hepatitis C infection can be an acute or chronic illness and is the most common cause of liver disease in the US. It often goes undiagnosed until significant organ damage has occurred. This issue of the ID Clinics discusses the staging of liver disease, treatments for those newly diagnosed, and those who are dealing with chronic illness, along with managing drug therapy and virus resistance.







A National Strategy for the Elimination of Hepatitis B and C


Book Description

Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the second of two, builds off the conclusions of the first report and outlines a strategy for hepatitis reduction over time and specific actions to achieve them.




Hepatitis B and C


Book Description

This book on Hepatitis B and C contains very useful and recent information about the general characteristics of these common types of chronic liver infections. Referred to as Hepatitis B, there are three chapters describing the main epidemiological, clinical, therapeutic, and prognosis aspects. The molecular variants for HBsAg, its genotyping, and their clinical implications are fully analyzed. The implications of coinfection Hepatitis B and C in HIV patients and their treatment are described. In relation to Hepatitis C, there are three chapters describing the general characteristics of this chronic viral infection. The challenges and strategies for access to treatment of Hepatitis C in Latin America are fully covered and these can be applied in other countries with similar epidemiological and financial problems for access to treatment on a large scale. The role of direct-acting antivirals (DAA) in the treatment of chronic Hepatitis C infection with liver cirrhosis is clearly documented.




Care of the Patient with Hepatitis C Virus Infection, an Issue of Infectious Disease Clinics


Book Description

Hepatitis C infection can be an acute or chronic illness and is the most common cause of liver disease in the US. It often goes undiagnosed until significant organ damage has occurred. This issue of the ID Clinics discusses the staging of liver disease, treatments for those newly diagnosed, and those who are dealing with chronic illness, along with managing drug therapy and virus resistance.




HBV, an Issue of Clinics in Liver Disease


Book Description

Hepatitis B continues to be a worldwide public health problem of major proportions, with over 10% of people in heavily populated endemic areas being chronic carriers of the virus. Enormous strides have been made in understanding the biology of HBV and in management. Overwhelming evidence demonstrates that long-term suppression of viral replication may prevent the dreaded long-term outcomes of this disease. Increasing numbers of drugs that can achieve this goal, without the high risk of emergent viral resistance that characterized treatment as recently as 5 years ago, are available and more will follow, but controversies abound about the most effective manner in which to use these agents and about which patients should be treated. Many experts believe we are moving into an era in which the spectrum of patients who we consider treatment candidates is expanding. A volume on our present understanding about the biology and immunology of HBV, along with a critical analysis of the complex therapeutic issues is most timely.