Heredity and Infection


Book Description

Ideas about the transmission of disease have long formed the core of modern biology and medicine. Heredity and Infection examines their development over the last century. Two scientific revolutions - the bacteriological revolution of the 1890s and the genetic revolution at the start of the twentieth century - acted as the catalysts of major change in our understanding of the causes of illness. As well as being great scientific achievements, these were social and political watersheds that reconfigured the medical and administrative means of intervention. By establishing a clear distinction between transmission by infection and genetic transmission, this shift was instrumental in separating hygiene from eugenism. The authors argue that the popular perception of such a sharp divide stabilized only after 1945 when the use of antibiotics to end epidemics became commonplace. For health professionals the separation has never become an absolute one, and the book examines the various blends of heredity and infection that have preoccupied biology, medicine and the social sciences. Heredity and Infection recontructs the changing epidemiology of such historically important pathologies as tuberculosis , cancer and AIDS. In doing so, it demonstrates the role of experimental models, medical practices and cultural images in the making of contemporary biochemical knowledge.




The Genetics of African Populations in Health and Disease


Book Description

A pioneering work that focuses on the unique diversity of African genetics, offering insights into human biology and genetic approaches.




Genetic Susceptibility to Infectious Diseases


Book Description

Infectious diseases are commonly regarded as a distinct category, with different causes and patterns than chronic or genetic disease. But in fact there are many varieties of genetic susceptibility to infection, the subject of this book, which will be divided into three sections: 1) concepts and methods, 2) genes and pathophysiologic mechanisms, and 3) infectious agents and diseases. No currently plubished text on either genetics or infectious diseases focuses on the genetic aspects of the special relationship between host and pathogen in the way envisioned for Section 1. No other work on the selected genes regulating immunity deals as systematically with the sequence variation/function relationships most pertinent to infection as planned for Section 2. And no other book gives as meaningful a picture of how these genes operate in infectious disease as Section 3 will.




Understanding Racial and Ethnic Differences in Health in Late Life


Book Description

As the population of older Americans grows, it is becoming more racially and ethnically diverse. Differences in health by racial and ethnic status could be increasingly consequential for health policy and programs. Such differences are not simply a matter of education or ability to pay for health care. For instance, Asian Americans and Hispanics appear to be in better health, on a number of indicators, than White Americans, despite, on average, lower socioeconomic status. The reasons are complex, including possible roles for such factors as selective migration, risk behaviors, exposure to various stressors, patient attitudes, and geographic variation in health care. This volume, produced by a multidisciplinary panel, considers such possible explanations for racial and ethnic health differentials within an integrated framework. It provides a concise summary of available research and lays out a research agenda to address the many uncertainties in current knowledge. It recommends, for instance, looking at health differentials across the life course and deciphering the links between factors presumably producing differentials and biopsychosocial mechanisms that lead to impaired health.




Assessing Genetic Risks


Book Description

Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.




Thalassaemia: The Biography


Book Description

Here is a complete history of Thalassaemia, the most common type of genetic disorder in the human population, and one of the first whose genetic basis was established. Treatment is also discussed as well at an assessment of how molecular approaches are impacting medicine. - Publisher.--




Biology for AP ® Courses


Book Description

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.




Immunodeficient Rodents


Book Description

This informative guide provides a comprehensive overview of the biology and care of immunodeficient rodents, which are essential for the study of human diseases and the development of new treatments. It is an invaluable resource for scientists, veterinarians, and animal care professionals. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.




Biologically Modified Justice


Book Description

A novel account of distributive justice which takes advances in the biomedical sciences and global aging seriously.




Case Studies in Immunology


Book Description

This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.