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Yeast Genetics

Author : Jeffrey S. Smith

Publisher : Humana Press

Page : 378 pages

File Size : 20,50 MB

Release : 2014-09-12

Category : Science

ISBN : 9781493913640

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Book Description

Yeast Genetics: Methods and Protocols is a collection of methods to best study and manipulate Saccharomyces cerevisiae, a truly genetic powerhouse. The simple nature of a single cell eukaryotic organism, the relative ease of manipulating its genome and the ability to interchangeably exist in both haploid and diploid states have always made it an attractive model organism. Genes can be deleted, mutated, engineered and tagged at will. Saccharomyces cerevisiae has played a major role in the elucidation of multiple conserved cellular processes including MAP kinase signaling, splicing, transcription and many others. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Yeast Genetics: Methods and Protocols will provide a balanced blend of classic and more modern genetic methods relevant to a wide range of research areas and should be widely used as a reference in yeast labs.



Retinal Degenerations

Author : Matthew M. LaVail

Publisher : Springer Science & Business Media

Page : 458 pages

File Size : 39,27 MB

Release : 2012-12-06

Category : Medical

ISBN : 1461500672

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Book Description

The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration. Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.



AFHRL-TR.

Author :

Publisher :

Page : 56 pages

File Size : 44,23 MB

Release : 1970

Category :

ISBN :

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NanoBioMedicine

Author : Shailendra K. Saxena

Publisher : Springer Nature

Page : 510 pages

File Size : 43,1 MB

Release : 2020-02-03

Category : Medical

ISBN : 9813298987

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Book Description

This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.



Valuation

Author : McKinsey & Company Inc.

Publisher : John Wiley & Sons

Page : 860 pages

File Size : 39,85 MB

Release : 2010-07-16

Category : Business & Economics

ISBN : 0470889934

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Book Description

The number one guide to corporate valuation is back and better than ever Thoroughly revised and expanded to reflect business conditions in today's volatile global economy, Valuation, Fifth Edition continues the tradition of its bestselling predecessors by providing up-to-date insights and practical advice on how to create, manage, and measure the value of an organization. Along with all new case studies that illustrate how valuation techniques and principles are applied in real-world situations, this comprehensive guide has been updated to reflect new developments in corporate finance, changes in accounting rules, and an enhanced global perspective. Valuation, Fifth Edition is filled with expert guidance that managers at all levels, investors, and students can use to enhance their understanding of this important discipline. Contains strategies for multi-business valuation and valuation for corporate restructuring, mergers, and acquisitions Addresses how you can interpret the results of a valuation in light of a company's competitive situation Also available: a book plus CD-ROM package (978-0-470-42469-8) as well as a stand-alone CD-ROM (978-0-470-42457-7) containing an interactive valuation DCF model Valuation, Fifth Edition stands alone in this field with its reputation of quality and consistency. If you want to hone your valuation skills today and improve them for years to come, look no further than this book.



Advanced Techniques in Diagnostic Microbiology

Author : Yi-Wei Tang

Publisher : Springer

Page : 760 pages

File Size : 40,5 MB

Release : 2018-11-09

Category : Medical

ISBN : 3319951114

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Book Description

In recent years, advanced molecular techniques in diagnostic microbiology have been revolutionizing the practice of clinical microbiology in the hospital setting. Molecular diagnostic testing in general and nucleic acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. It is divided into two distinct volumes, with Volume 1 describing the techniques, and Volume 2 addressing their applications in the field. In addition, both volumes focus more so on the clinical relevance of the test results generated by these techniques than previous editions.



Evidence-based Dementia Practice

Author : Nawab Qizilbash

Publisher : John Wiley & Sons

Page : 0 pages

File Size : 39,83 MB

Release : 2002-05-06

Category : Medical

ISBN : 9780632052967

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Book Description

The era of therapeutic nihilism in dementia has ended, with the emergence of agents for symptomatic treatment, those that delay the course of the disease or prevent the onset of dementia, and new methods to manage symptoms. With the expansion of therapies, there is a clear danger of being overwhelmed by the volume of data. This book is designed to collect this information, distil what is relevant and reliable, and present it in a format that is useful to clinicians who manage and treat people with dementia. The book is designed to bring together the latest, best and practical evidence on all aspects of management, from diagnosis and therapy to social and ethical considerations. The editors are all dynamic clinicians involved in the care of patients with dementia and the evaluation of therapies. Two of the editors are the leaders of the Cochrane Collaboration for the examination of therapies for dementia. There are no other books that take such a practical and problem-oriented or approach to the diagnosis and management of dementia. Furthermore none but this can be described as truely evidence-based.



A Frequency Dictionary of German

Author : Randall Jones

Publisher : Routledge

Page : 200 pages

File Size : 23,38 MB

Release : 2015-06-03

Category : Foreign Language Study

ISBN : 1135182965

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Book Description

A Frequency Dictionary of German is an invaluable tool for all learners of German, providing a list of the 4,034 most frequently used words in the language. Based on a 4.2 million-word corpus which is evenly divided between spoken, fiction and non-fiction texts, the dictionary provides a detailed frequency-based list plus alphabetical and part of speech indexes. All entries in the rank frequency list feature the English equivalent, a sample sentence plus an indication of major register variation. The dictionary also contains twenty-one thematically organized lists of frequently used words on a variety of topics as well as eleven special vocabulary lists. A Frequency Dictionary of German aims to enable students of all levels to maximize their study of German vocabulary in an efficient and engaging way.



Molecular Markers of Brain Tumor Cells

Author : Bela Bodey

Publisher : Springer Science & Business Media

Page : 396 pages

File Size : 26,57 MB

Release : 2004-09-14

Category : Medical

ISBN : 9781402027819

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Book Description

I. MOLECULAR BIOLOGY OF TUMORS. 1. Brain Tumors 2. Immunophenotypic Characterization of Infiltrating Poly- and Mononuclear Cells in Childhood Brain Tumors II. ANTI-NEOPLASTIC BIOLOGICAL THERAPIES 3. Experimental Therapies in Brain Tumors 4. Biologic Anti-Neoplastic Therapies 5. The lymphokine activated killer (LAK) cell phenomenon 6. Angiogenesis Inhibition in Anti-Neoplastic Therapy 7. Antigen Presentation by Dendritic Cells and Their Significance in Anti-Neoplastic Immunotherapy 8. Genetically Engineered Antibodies for Direct Anti-Neoplastic Treatment and Systematic Delivery of Various Therapeutic Agents to Cancer Cells 9. Cancer-Testis Antigens: Promising Targets for Antigen Directed Anti-neoplastic Immunotherapy III. APPENDIX 10. Materials and Methods



Networking for Nerds

Author : Alaina G. Levine

Publisher : John Wiley & Sons

Page : 256 pages

File Size : 49,54 MB

Release : 2015-05-13

Category : Science

ISBN : 1118663551

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Book Description

Networking for Nerds provides a step-by-step guide to understanding how to access hidden professional opportunities through networking. With an emphasis on practical advice on how and why to network, you will learn how to formulate and execute a strategic networking plan that is dynamic, multidimensional, and leverages social media platforms and other networking channels. An invaluable resource for both established and early-career scientists and engineers (as well as networking neophytes!), Networking for Nerds offers concrete insight on crafting professional networks that are mutually beneficial and support the advancement of both your career goals and your scholarly ambitions. “Networking” does not mean going to one reception or speaking with a few people at one conference, and never contacting them again. Rather, “networking” involves a spectrum of activities that engages both parties, ensures everyone’s value is appropriately communicated, and allows for the exploration of a win-win collaboration of some kind. Written by award-winning entrepreneur and strategic career planning expert Alaina G. Levine, Networking for Nerds is an essential resource for anyone working in scientific and engineering fields looking to enhance their professional planning for a truly fulfilling, exciting, and stimulating career. professional planning for a truly fulfilling, exciting, and stimulating career.Networking for Nerds provides a step-by-step guide to understanding how to access hidden professionalopportunities through networking. With an emphasis on practical advice on how and why to network, youwill learn how to formulate and execute a strategic networking plan that is dynamic, multidimensional, andleverages social media platforms and other networking channels.An invaluable resource for both established and early-career scientists and engineers (as well as networkingneophytes!), Networking for Nerds offers concrete insight on crafting professional networks that aremutually beneficial and support the advancement of both your career goals and your scholarly ambitions.“Networking” does not mean going to one reception or speaking with a few people at one conference, andnever contacting them again. Rather, “networking” involves a spectrum of activities that engages bothparties, ensures everyone’s value is appropriately communicated, and allows for the exploration of a win-wincollaboration of some kind.Written by award-winning entrepreneur and strategic career planning expert Alaina G. Levine, Networking forNerds is an essential resource for anyone working in scientific and engineering fields looking to enhance theirprofessional planning for a truly fulfilling, exciting, and stimulating career.