Hormones as Tokens of Selection


Book Description

Hormones as Tokens of Selection addresses deep questions in biology: How are biological systems controlled? How can one formulate general theories of homeostasis and control and instantiate such theories in mathematical models? How can one use evolutionary arguments to guide our answers to these questions, recognising that the control mechanisms themselves are a product of evolution? Biological systems are exceptionally varied and extremely difficult to understand, because they are complex and experimentation remains limited relative to the challenges at hand. Moreover, biological phenomena occur at a wide range of temporal and spatial scales. Such a deeply convoluted subject calls for a unifying and coherent theoretical foundation — one which recognises and departs from the primary importance of mathematical modelling and key physicochemical principles to theory formation in the life sciences. This Focus monograph proposes and outlines such a foundation, departing from the deceptively simple proposition that hormones are tokens of evolutionary pressures. Features Provides a coherent and unified approach to a multifaceted problem Pays close attention to both the biological and mathematical modelling aspects of the subject matter, exploring the philosophical background where appropriate Written in a concise and innovative style




Hormones as Tokens of Selection


Book Description

Hormones as Tokens of Selection addresses deep questions in biology: How are biological systems controlled? How can one formulate general theories of homeostasis and control and instantiate such theories in mathematical models? How can one use evolutionary arguments to guide our answers to these questions, recognising that the control mechanisms themselves are a product of evolution? Biological systems are exceptionally varied and extremely difficult to understand, because they are complex and experimentation remains limited relative to the challenges at hand. Moreover, biological phenomena occur at a wide range of temporal and spatial scales. Such a deeply convoluted subject calls for a unifying and coherent theoretical foundation — one which recognises and departs from the primary importance of mathematical modelling and key physicochemical principles to theory formation in the life sciences. This Focus monograph proposes and outlines such a foundation, departing from the deceptively simple proposition that hormones are tokens of evolutionary pressures. Features Provides a coherent and unified approach to a multifaceted problem Pays close attention to both the biological and mathematical modelling aspects of the subject matter, exploring the philosophical background where appropriate Written in a concise and innovative style




Genetics of Mate Choice: From Sexual Selection to Sexual Isolation


Book Description

Genetic studies aimed at understanding the origin of species are dominating major scientific journals. In the past decade, genetic tools that were previously available only in model systems have become accessible to investigators working on nearly all species. Concurrent with these technical advances has been an increase in understanding of both the importance of considering the ecological context of speciation and testing hypotheses about causes for species formation. Many recent studies suggest a prominent role of sexual selection in species formation. These advances have produced a need for a synthesis of what we now understand about speciation, and perhaps more importantly, where we should go from here. In this volume, several leading investigators and rising stars have contributed reviews and/or novel primary research findings aimed at understanding the ultimate mystery on which Darwin named his most famous and influential book. Fundamental to the origin of species is the evolution of mate choice systems. This collection of papers discusses burgeoning genetic, evolutionary, and ecological approaches to understanding the origins of mating discrimination and causes of premating reproductive isolation both within and between species. The individual contributions span a wide spectrum of disciplines, taxa, and ideas (some controversial). This synthesis brings together several of the most recent ideas with supporting empirical data. This book will be of particular interest to both undergraduate and postgraduate researchers and students and researchers in the field of evolutionary biology, genetics and animal behaviour.




Selection Day


Book Description

From the bestselling, Booker Prize-winning author of The White Tiger and Amnesty, a “ferociously brilliant” (Slate) novel about two brothers coming of age in a Mumbai slum, raised by their crazy, obsessive father to be cricket champions. *A NETFLIX ORIGINAL SERIES * AN NPR BEST BOOK OF THE YEAR * A NEW YORK TIMES and WASHINGTON POST NOTABLE BOOK Manjunath Kumar is fourteen and living in a slum in Mumbai. He knows he is good at cricket—if not as good as his older brother, Radha. He knows that he fears and resents his domineering and cricket-obsessed father, admires his brilliantly talented sibling, and is fascinated by curious scientific facts and the world of CSI. But there are many things, about himself and about the world, that he doesn’t know. Sometimes it even seems as though everyone has a clear idea of who Manju should be, except Manju himself. When Manju meets Radha’s great rival, a mysterious Muslim boy privileged and confident in all the ways Manju is not, everything in Manju’s world begins to change, and he is faced by decisions that will challenge his sense of self and of the world around him. Filled with unforgettable characters from across India’s social strata—the old scout everyone calls Tommy Sir; Anand Mehta, the big-dreaming investor; Sofia, a wealthy, beautiful girl and the boys’ biggest fan—Selection Day “brings a family, a city, and an entire country to scabrous and antic life” (Chicago Tribune).




Please Select Your Gender


Book Description

"I have the worst birth defect a woman can have: I was born with a penis and a pair of testicles." Thus we meet Hera, who shares her reason for starting psychoanalysis and whose statement embodies the debate over transgenderism, rigorously dissected in Please Select Your Gender. Is it a mental disorder, as some would claim, or a matter of sexual identity? An orientation or a life choice? Despite differing opinions, transgenderism has lost much of its stigma over the past decade or so – though perhaps none of its shock value. Nevertheless, the door is open for a reformulation of the hysterical question, "Am I a man or a woman?" Utilizing rich clinical vignettes and elements of Lacanian theory, Patricia Gherovici demonstrates how the transgender discourse has both reoriented psychoanalytic practice and reframed debates about gender in American society at large. She traverses historical, theoretical, and clinical grounds to explore what has been termed the "democratizing of gender" – for what could be more democratic than the choice of one’s own gender, now able to be changed on demand? Arguing for the depathologization of transgenderism, Please Select Your Gender aims to revise current notions of human sexuality in general. In doing so, it challenges the theory and practice of psychoanalysis with questions typically addressed only indirectly, but which are themselves transforming how analysis is done, advancing new ideas for the clinic that can be extrapolated to social and intellectual contexts in an effort to engage the broader dialogues of gender and sexuality.




Selected Topics from Neurochemistry


Book Description

This book contains up-dated versions of articles which proved very popular when first published in Neurochemistry International. The articles draw attention to developments in a specific field perhaps unfamiliar to the reader, collating observations from a wide area which seem to point in a new direction, giving the author's personal view on a controversial topic, or directing soundly based criticism at some widely held dogma or widely used technique in the neurosciences.




Hormones and Economic Behavior


Book Description

Behavioral correlates of hormones, emphasized by psychologists, have captured the attention of economists in the past years. Behavioral economists, in particular, have investigated the possible roles of hormones on economic decision making and behavior as well as social preferences and cognitive abilities. Testosterone, oxytocin, dopamine, serotonin and stress hormones are the foremost studied ones in economic contexts. Yet, the results are mixed and the relationship between hormones and economic behavior is under-investigated to this date. Hormone levels are measurable and manipulatable (e.g. activate, de-activate, block). The fact that the behavioral economics also employs experimental methodology makes it possible to observe both correlational and causal relationships between hormones and economic behavior. Since numerous environmental, social and biological factors interact with hormone fluctuations, capturing the true impacts of hormones on decisions and behavior is challenging. Manipulating hormone levels in the body is a method that is used to tackle this issue. Such studies compare observed behaviors of hormones or placebo administrated participants to determine causal relationships. This Research Topic welcomes the studies on the direct or indirect correlates of hormones on economic behavior and decision making to create new insights on the economic consequences of endocrine activity.




Hormones, Brain and Behavior


Book Description

Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Contributors from 16 different countries and more than 70 institutions Unlike any other hormone reference on the market Hormones, Brain and Behavior addresses hormone effects in all major vertebrate and non-vertebrate models A timely, current reference on an emerging field with each chapter providing an in-depth exploration of the topic Discusses molecular aspects of hormone function, systems, development, and hormone-related diseases Addresses hormone effects in both the developing and adult nervous system Topics include: Mammalian and Non-mammalian Hormone-behavior Systems Cellular and Molecular Mechanisms of Hormone Actions on Behavior Development of Hormone-dependent Neuronal Systems Hormone/Behavior Relations of Clinical Importance







Growth Hormone And The Heart


Book Description

Growth Hormone and the Heart endeavors to bring together knowledge that has been accumulated in the area of GH and the heart, from basic to clinical studies, by research groups working on this topic throughout the world. Lessons from different experimental models and from several human diseases (acromegaly, adult GH deficiency, heart failure) suggest to endocrinologists and cardiologists that GH may not only have a role in the physiology and pathophysiology of heart function, but that GH itself may have a place in the treatment of primary heart diseases (such as dilated cardiomyopathy) or of cardiac complications of hypopituitarism. Growth Hormone and the Heart will be a useful update of the research produced in the field of cardiovascular endocrinology. The Editors also hope that this book will serve as the primary step in the recognition of the wide physiological and clinical significance of GH and heart interactions.