Human Airway Smooth Muscle
Author : Johannes Cornelis Jongste
Publisher :
Page : 218 pages
File Size : 21,53 MB
Release : 1987
Category :
ISBN : 9789090019284
Author : Johannes Cornelis Jongste
Publisher :
Page : 218 pages
File Size : 21,53 MB
Release : 1987
Category :
ISBN : 9789090019284
Author : Kristen Mae Hawker
Publisher :
Page : 324 pages
File Size : 34,38 MB
Release : 1999
Category : Airway (Medicine)
ISBN :
Author : Trang T. B. Nguyen
Publisher :
Page : 602 pages
File Size : 19,10 MB
Release : 2004
Category :
ISBN :
Author : Wim Wuyts
Publisher : Leuven University Press
Page : 172 pages
File Size : 44,5 MB
Release : 2003
Category : Asthma
ISBN : 9789058673510
"This is a Ph.D. dissertation. Because of the worldwide burden of bronchial asthma and the recent increase in the use of lung transplantation as a treatment for end-stage lung disease, the importance of chronic inflammatory airway diseases, such as asthma "
Author : Anthonie Ruthmus Hulsmann
Publisher :
Page : 223 pages
File Size : 31,27 MB
Release : 1995
Category :
ISBN : 9789090087740
Author : R.F. Coburn
Publisher : Springer Science & Business Media
Page : 325 pages
File Size : 17,97 MB
Release : 2012-12-06
Category : Science
ISBN : 1461307791
I organized this book because there is a need to put together in book form recent advances in our knowledge of how airway smooth muscle:works in health and in disease. After a period when it seemed that progress was very slow, there has been in the past few years an incredibly rapid gathering of knowledge in this area. In particular, our understanding has improved regarding the cascades of events that follow the initial binding of agonist to plasma membrane receptors and that lead to the cross-bridge movements that determine contraction. This advance in our knowledge was stimulated by use of single-and whole-cell channel recordings of plasma membrane currents and by description of the l3-receptor-GTP-binding protein-adenylate cyclase-cAMP coupling system, which serves as a model for other coupling mechanisms. The discovery of the receptor-activated inositol phospholipid transduction system has greatly stimulated research and led to advances in our understanding of mechanisms involved in smooth muscle con traction. Major advances were also triggered by the development of indicators for measuring free cytosolic calcium concentration and starting the unraveling of 2 the events involved in Ca + -dependent activation of contractile proteins. Al though most of the studies that led to our current understanding of these areas were performed on nonairway smooth muscle, these studies usually add to our understanding of airway smooth muscle, and there is an enlarging body of data that have been obtained on airway smooth muscle.
Author : Devendra K. Agrawal
Publisher : CRC Press
Page : 320 pages
File Size : 10,29 MB
Release : 1990-10-24
Category : Medical
ISBN : 9780849359040
Airway smooth muscle plays a dominant role in bronchial asthma, as well as a significant role in various pulmonary diseases, such as chronic bronchitis, cystic fibrosis and emphysema. Myogenic, neurogenic, and humoral factors control airway smooth-muscle tone. This text provides a state-of-the-art summary and critical discussion of airway smooth muscle from a multidisciplinary point of view. Topics discussed include morphology, biochemical regulation, mechanical and electrophysiological behavior and reflex control of smooth muscle; the epithelium-derived relaxing factor; and methods to measure smooth muscle function in vivo in humans and experimental animals, as well as in vitro in isolated airway tissues. Also discussed are calcium and potassium channels and receptors for adrenergic, cholinergic and histaminergic systems in modulating receptor-response coupling in airway smooth muscle. Airway Smooth Muscle: Modulation of Receptors and Response provides essential information for researchers, teachers, pulmonary specialists and allergists, and students interested in learning about airway smooth muscle.
Author : Kian Fan Chung
Publisher : John Wiley & Sons
Page : 326 pages
File Size : 43,82 MB
Release : 2008-04-30
Category : Science
ISBN : 0470754214
In this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be modified are discussed and future therapeutic interventions are identified. Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offers insights into current and future approaches to management. Authoritative update on key mechanisms of airway constriction in Asthma and COPD Relates latest research to bronchodilator therapy Multi-contributed text, co-coordinated by two of the leading authorities in the field.
Author : David Sweeney
Publisher :
Page : pages
File Size : 37,96 MB
Release : 2011
Category :
ISBN :
Author : Celso Pereira
Publisher : BoD – Books on Demand
Page : 146 pages
File Size : 34,54 MB
Release : 2019-10-02
Category : Medical
ISBN : 1789843154
Asthma is a prevalent disease in all age groups that results from different pathogenic mechanisms, cells, and mediators engaged in innumerous clinical phenotypes and endotypes. This book exhaustively and didactically explores the biological expression of numerous cells and mediators involved in bronchial inflammation. The information provided aims at identifying the diversity and complexity of the interrelationships between the different players, drawing attention to critical mechanisms in asthma. It also highlights the requirement of new tools to identify strong biomarkers absolutely critical for managing asthma.