› › Human Gametes And Preimplantation Embryos

Human Reproduction

Author : Heide Schatten

Publisher : John Wiley & Sons

Page : 454 pages

File Size : 14,65 MB

Release : 2017-03-06

Category : Science

ISBN : 1118849582

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Book Description

In vitro fertilization (IVF) and other assisted reproductive technologies (ART) have become a significant part of human reproduction, with already one in 50 children worldwide being born through ART and the demand steadily increasing. To accommodate the various kinds of infertility problems, new methods have been developed to increase IVF and ART success rates and it has also become possible to treat sperm, eggs, and embryos in culture to improve reproductive success, to increase the health state of an embryo, and to prevent disease in the developing child. Human Reproduction: Updates and New Horizons focuses on recent developments and new approaches to study egg and sperm cells and embryo development, as well as addressing the increasing demand for IVF and ART to overcome infertility problems of various kinds that are encountered by an increasing number of couples worldwide. The book includes 10 chapters written by experts in their specific fields to provide information on sperm selection techniques and their relevance to ART; In vitro maturation of human oocytes: current practices and future promises; Molecular biology of endometriosis; Novel immunological aspects for the treatment of age-induced ovarian and testicular infertility, other functional diseases, and early and advanced cancer immunotherapy; Mitochondrial manipulation for infertility treatment and disease prevention; Novel imaging techniques to assess gametes and preimplantation embryos; Clinical application of methods to select in vitro fertilized embryos; New horizons/developments in time-lapse morphokinetic analysis of mammalian embryos; The non-human primate model for early human development; Cytoskeletal functions, defects, and dysfunctions affecting human fertilization and embryo development. This book will appeal to a large interdisciplinary audience, including researchers from both the basic science and medical communities. It will be a valuable reference for IVF clinicians, patients and prospective patients who are considering ART procedures, embryologists, cell biologists and students in the field of reproduction.



Human Gametes and Preimplantation Embryos

Author : David K. Gardner

Publisher : Springer Science & Business Media

Page : 307 pages

File Size : 27,38 MB

Release : 2013-05-27

Category : Health & Fitness

ISBN : 1461466512

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Book Description

In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.



Heritable Human Genome Editing

Author : The Royal Society

Publisher : National Academies Press

Page : 239 pages

File Size : 38,20 MB

Release : 2021-01-16

Category : Medical

ISBN : 0309671132

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Book Description

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.



Gamete and Embryo-fetal Origins of Adult Diseases

Author : He-Feng Huang

Publisher : Springer Science & Business Media

Page : 229 pages

File Size : 45,64 MB

Release : 2013-11-19

Category : Health & Fitness

ISBN : 9400777728

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Book Description

The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians. Editor He-Feng Huang, M.D., is Professor and President of Women’s Hospital, School of Medicine, Zhejiang University, China. Editor Jian-Zhong Sheng, Ph.D., is Professor at the Department of Pathology & Pathophysiology, School of Medicine, Zhejiang University, China.



Blastocyst Implantation

Author : Koji Yoshinaga

Publisher : Adams Publishing Group

Page : 264 pages

File Size : 35,98 MB

Release : 1989

Category : Medical

ISBN :

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Human Preimplantation Embryo Selection

Author : Jacques Cohen

Publisher : CRC Press

Page : 386 pages

File Size : 33,30 MB

Release : 2007-09-26

Category : Medical

ISBN : 0203089715

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Book Description

The most profound dilemma in assisted reproduction to date is the inability to recognize potentially viable embryos before their replacement into the reproductive tract. Application of increasingly advanced new technology has allowed the field of embryo evaluation to evolve rapidly and dramatically over the past five years.Human Preimplantation Emb



Scientific and Medical Aspects of Human Reproductive Cloning

Author : National Research Council

Publisher : National Academies Press

Page : 295 pages

File Size : 10,39 MB

Release : 2002-06-17

Category : Science

ISBN : 0309076374

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Book Description

Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.



Assisted Reproductive Technology Surveillance

Author : Dmitry M. Kissin

Publisher : Cambridge University Press

Page : 255 pages

File Size : 37,74 MB

Release : 2019-07-04

Category : Health & Fitness

ISBN : 1108498582

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Book Description

Offers a comprehensive guide to assisted reproductive technology surveillance, describing its history, global variations, and best practices.



Readings in Health Care Ethics - Second Edition

Author : Elisabeth (Boetzkes) Gedge

Publisher : Broadview Press

Page : 675 pages

File Size : 27,96 MB

Release : 2012-03-14

Category : Philosophy

ISBN : 1554810388

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Book Description

Readings in Health Care Ethics provides a wide-ranging selection of important and engaging contributions to the field of health care ethics. The second edition adds a chapter on health care in Canada, and the introduction has been expanded to include discussion of a new direction in feminist naturalized ethics. The book presupposes no prior knowledge, only an interest in the bioethical issues that are shaping our world.



An Atlas of Human Gametes and Conceptuses

Author : Lucinda L. Veeck

Publisher : CRC Press

Page : 216 pages

File Size : 43,41 MB

Release : 1999-04-15

Category : Medical

ISBN : 9781850700166

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Book Description

Replacing and superseding all other works in this area, Dr. Lucinda L. Veeck's An Atlas of Human Gametes and Conceptuses is the only book now in print that shows the typical and atypical morphology of human oocytes, sperm, and preembryos collected and cultured during the course of in vitro fertilization treatment. Brilliantly illustrated with hundreds of original photographs in color as well as black and white, the book also details and fully illustrates specific new reproductive technologies and provides the reader with both a glossary and a concise history of in vitro fertilization. Includes bibliographic references and index.