Human Haemoglobin Variants and Their Characteristics
Author : Hermann Lehmann
Publisher : North-Holland
Page : 258 pages
File Size : 24,38 MB
Release : 1976
Category : Medical
ISBN :
Author : Hermann Lehmann
Publisher : North-Holland
Page : 258 pages
File Size : 24,38 MB
Release : 1976
Category : Medical
ISBN :
Author : L. H. B. Wallett
Publisher :
Page : 56 pages
File Size : 28,35 MB
Release : 1968
Category : Hemoglobin
ISBN : 9780407731103
Author : Martin H. Steinberg
Publisher : Cambridge University Press
Page : 883 pages
File Size : 46,89 MB
Release : 2009-08-17
Category : Medical
ISBN : 0521875196
Completely revised new edition of the definitive reference on disorders of hemoglobin.
Author : Howard Franklin Bunn
Publisher : W.B. Saunders Company
Page : 456 pages
File Size : 24,53 MB
Release : 1977
Category : Medical
ISBN :
Since the dawn of the era of molecular biology, hemoglobin has been subjected to more scrutiny than any other protein, and Bunn, Forget, and Ranney can each lay claim to major contributions to the saga of hemoglobin. Their well-organized, comprehensive, and superbly illustrated work is an excellent review of the abnormal hemoglobin field. Early chapters deal with the structure and function of human hemoglobin and the way in which this is modified in various disease states. Later sections deal with the various structural hemoglobin variants and their associated clinical manifestations, the thalassaemias, and the acquired disorders of hemoglobin. The sections that deal with the modification of hemoglobin function in various disease states are particularly good. The book contains an extensive and up-to-date bibliography and is remarkably free from errors of fact or type--the best standard of reference on the subject as of the year 1977.
Author : Frank. B. Livingstone
Publisher : Routledge
Page : 421 pages
File Size : 30,41 MB
Release : 2019-01-15
Category : Medical
ISBN : 135153436X
Research on abnormal human hemoglobins (protein in blood that carries oxygen), has taught us about the inheritance, biochemistry, and distribution of these traits. This knowledge, coupled with mathematical research using computer models of population genetics, has enabled researchers to marry biological fact and genetic theory. This volume places medical understanding in an evolutionary framework. Using published data on the frequencies of abnormal hemoglobins in the world's populations, Livingston analyzes and interprets these frequencies in the light of world distribution of different forms of diseases such as malaria. He further develops the genetic theory of the evolutionary homeostasis. Livingston discusses the relation of abnormal hemoglobins to endemic malaria and, shows how natural selection pressures explain the known distribution of these traits. Where non-coinciding distributions arise, the book presents other genetic, anthropological, evolutionary, and epidemiological evidence to explain these discrepancies. This classic work remains a useful sourcebook for professors and graduate students of anthropology, genetics, epidemiology, and hematology.
Author : L. H. B. Wallet
Publisher :
Page : 0 pages
File Size : 14,84 MB
Release : 1968
Category :
ISBN :
Author : David J. Weatherall
Publisher : John Wiley & Sons
Page : 864 pages
File Size : 45,4 MB
Release : 2008-04-30
Category : Medical
ISBN : 0470695943
In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in the laboratory or clinical setting, particularly in areas where thalassaemia is common either in the native population or in immigrant communities. The fourth edition has been both updated and re-organized. Three new chapters have been added on the link between alpha-thalassaemia and mental retardation, on avoidance and population control and on global epidemiology. Considerable emphasis is placed on molecular pathology reflecting the huge burst of information to have come out of this field in the last few years.
Author : Brian N. Green
Publisher :
Page : 482 pages
File Size : 37,35 MB
Release : 2021
Category : Hemoglobin
ISBN : 9781526208958
Author : Galanello Renzo
Publisher :
Page : 190 pages
File Size : 15,11 MB
Release : 2003
Category :
ISBN : 9789963623396
Volume 1 of the Prevention Book presents the principles of a programme for the prevention of the thalassaemia and other haemoglobin disorders, including a description of the various types of disorders requiring prenatal diagnosis, the strategies used for carrier screening, and a number of annexes listing upto date epidemiological and mutation data on thalassaemia. This book was written for use in combination with Volume 2, which describes many of the laboratory protocols in great detail.
Author : Roland N. Pittman
Publisher : Biota Publishing
Page : 117 pages
File Size : 40,44 MB
Release : 2016-08-18
Category : Medical
ISBN : 1615047212
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.