Impacts of natural disasters on supply chain performance


Book Description

Considering the increasing importance of natural disaster events it is inevitable to also focus on their impacts on supply chains as well as their performance impacts on them. The developed approach SCperformND (Supply Chain performance impact assessment of Natural Disasters) demonstrates a methodology to assess those impacts and gives implications for supply chain designs and procurement decisions.







Metrics for Process Models


Book Description

Business process modeling plays an important role in the management of business processes. As valuable design artifacts, business process models are subject to quality considerations. The absence of formal errors such as deadlocks is of paramount importance for the subsequent implementation of the process. In his book Jan Mendling develops a framework for the detection of formal errors in business process models and the prediction of error probability based on quality attributes of these models (metrics). He presents a precise description of Event-driven Process Chains (EPCs), their control-flow semantics and a suitable correctness criterion called EPC soundness.




HSF1 and Molecular Chaperones in Biology and Cancer


Book Description

Protein homeostasis, or “Proteostasis”, lies at the heart of human health and disease. From the folding of single polypeptide chains into functional proteins, to the regulation of intracellular signaling pathways, to the secreted signals that coordinate cells in tissues and throughout the body, the proteostasis network operates to support cell health and physiological fitness. However, cancer cells also hijack the proteostasis network and many of these same processes to sustain the growth and spread of tumors. The chapters in this book are written by world experts in the many facets of the proteostasis network. They describe cutting-edge insights into the structure and function of the major chaperone and degradation systems in healthy cells and how these systems are co-opted in cancer cells and the cells of the tumor microenvironment. The chapters also cover therapeutic interventions such as the FDA-approved proteasome inhibitors Velcade and Krypolis as well as other therapies currently under clinical investigation to disarm the ability of the proteostasis network to support malignancy. This compendium is the first of its kind and aims to serve as a reference manual for active investigators and a primer for newcomers to the field. This book is dedicated to the memory of Susan Lindquist, a pioneer of the proteostasis field and a champion of the power of basic scientific inquiry to unlock the mechanisms of human disease. The chapter “Reflections and Outlook on Targeting HSP90, HSP70 and HSF1 in Cancer: A Personal Perspective” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.




Understanding Power Quality Problems


Book Description

Power quality problems have increasingly become a substantial concern over the last decade, but surprisingly few analytical techniques have been developed to overcome these disturbances in system-equipment interactions. Now in this comprehensive book, power engineers and students can find the theoretical background necessary for understanding how to analyze, predict, and mitigate the two most severe power disturbances: voltage sags and interruptions. This is the first book to offer in-depth analysis of voltage sags and interruptions and to show how to apply mathematical techniques for practical solutions to these disturbances. From UNDERSTANDING AND SOLVING POWER QUALITY PROBLEMS you will gain important insights into Various types of power quality phenomena and power quality standards Current methods for power system reliability evaluation Origins of voltage sags and interruptions Essential analysis of voltage sags for characterization and prediction of equipment behavior and stochastic prediction Mitigation methods against voltage sags and interruptions Sponsored by: IEEE Power Electronics Society, IEEE Industry Applications Society, IEEE Power Engineering Society.




Power System Transients


Book Description

Despite the powerful numerical techniques and graphical user interfaces available in present software tools for power system transients, a lack of reliable tests and conversion procedures generally makes determination of parameters the most challenging part of creating a model. Illustrates Parameter Determination for Real-World Applications Geared toward both students and professionals with at least some basic knowledge of electromagnetic transient analysis, Power System Transients: Parameter Determination summarizes current procedures and techniques for the determination of transient parameters for six basic power components: overhead line, insulated cable, transformer, synchronous machine, surge arrester, and circuit breaker. An expansion on papers published in the IEEE Transactions on Power Delivery, this text helps those using transient simulation tools (e.g., EMTP-like tools) to select the optimal determination method for their particular model, and it addresses commonly encountered problems, including: Lack of information Testing setups and measurements that are not recognized in international standards Insufficient studies to validate models, mainly those used in high-frequency transients Current built-in models that do not cover all requirements Illustrated with case studies, this book provides modeling guidelines for the selection of adequate representations for main components. It discusses how to collect the information needed to obtain model parameters and also reviews procedures for deriving them. Appendices summarize updated techniques for identifying linear systems from frequency responses and review capabilities and limitations of simulation tools. Emphasizing standards, this book is a clear and concise presentation of key aspects in creating an adequate and reliable transient model.




Mass Transfer-II


Book Description

Distillation - Liquid-Liquid Extraction - Adsorption and Ion Exchange - Leaching - Crystallisation - Drying - Appendix - I




Towards Personalized Medicine for Cancer, Volume 1210


Book Description

This volume explores cancer as an individualized problem and addresses the impact of recent advances in cancer biology, genetics, tumor profiling, and medical technology in the personalization of cancer predisposition, diagnosis, prognosis, treatment, and therapy development. Featuring contributionsfrom basic and clinical scientists, this volume brings together work from different areas of individualized oncology to help improve the global concept of the personalized cancer care, and identify commonalities, pitfalls, and steps forward. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.




Advanced Materials and Manufacturing Processes


Book Description

This book discusses advanced materials and manufacturing processes with insights and overviews on tribology, automation, mechanical, biomedical, and aerospace engineering, as well as the optimization of industrial applications. The book explores the different types of composite materials while reporting on the design considerations and applications of each. Offering an overview of futuristic research areas, the book examines various engineering optimization and multi-criteria decision-making techniques and introduces a specific control framework used in analyzing processes. The book includes problem analyses and solving skills and covers different types of composite materials, their design considerations, and applications. This book is an informational resource for advanced undergraduate and graduate students, researchers, scholars, and field professionals, providing an update on the current advancements in the field of manufacturing processes.




Spectral Audio Signal Processing


Book Description

"Spectral Audio Signal Processing is the fourth book in the music signal processing series by Julius O. Smith. One can say that human hearing occurs in terms of spectral models. As a result, spectral models are especially useful in audio applications. For example, with the right spectral model, one can discard most of the information contained in a sound waveform without changing how it sounds. This is the basis of modern audio compression techniques."--Publisher's description.