Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry


Book Description

Imaging mass spectrometry (MS) techniques are often utilized without an understanding of their underlying principles, making it difficult for scientists to determine when and how they can exploit MS to visualize their biomolecules of interest. Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry is an essential reference to help scientists determine the status and strategies of biomolecule analysis, describing its many applications for diverse classes of biomolecules. The book builds a foundation of imaging MS knowledge by introducing ionization sources, sample preparation, visualization guidelines, molecule identification, quantification, data analysis, etc. The second section contains chapters focused on case studies on analyzing a biomolecule class of molecules. Case studies include an introduction/background, and a summary of successful imaging MS studies with illustrative figures and future directions. - Provides the introductory foundations of imaging mass spectrometry for those new to the technique - Organized by topic to facilitate a quick deep dive, allowing researchers to immediately apply the imaging MS techniques to their work - Includes case studies summarizing the imaging MS techniques developed for the class of molecules




Imaging Spectrometry III


Book Description




Imaging Spectrometry -- a Tool for Environmental Observations


Book Description

The technique of imaging spectrometry has now passed its infancy and entered into a new phase of application oriented research. Advanced sensor systems (such as Nasa/JPL's AVIRIS) have become available for international research programmes (MAC Europe 1991), new imaging spectrometers are under development in several European countries or have already passed their acceptance tests, and first high spectral resolution imaging systems are already operated by private industry. On European level, the EARSEC programme of the Joint Research Centre has provided considerable financial investments for the development of an imaging spectrometer which covers the reflective and important parts of the emissive spectrum (DAIS-7915), and the European Space Agency has initiated an important airborne remote sensing campaign (EMAC 1994/95) in which imaging spectrometry will constitute one of the most important components. The increasing sensor capabilities also reflect the fact that imaging spectrometry has advanced in many application fields of earth remote sensing. Progress has been made in the development of data pre-proeessing methods, spectral signature modeling and semi-empirical approaches for retrieving surface parameters. It therefore appeared important to further disseminate information about new approaches in the application-oriented analysis of imaging spectrometry data. This volume presents the lectures of the second EUROCOURSE on imaging spectrometry which was held in November 1992 at the Joint Research Centre (a first course on "Fundamentals and Prospective Applications" of imaging spectrometry had been organised in October 1989, the lectures being published as EUROCOURSES in Remote Sensing, vol. 2).




Imaging Spectrometry


Book Description

A significant step forward in the world of earth observation was made with the development of imaging spectrometry. Imaging spectrometers measure reflected solar radiance from the earth in many narrow spectral bands. Such a spectroscopical imaging system is capable of detecting subtle absorption bands in the reflectance spectra and measure the reflectance spectra of various objects with a very high accuracy. As a result, imaging spectrometry enables a better identification of objects at the earth surface and a better quantification of the object properties than can be achieved by traditional earth observation sensors such as Landsat TM and SPOT. The various chapters in the book present the concepts of imaging spectrometry by discussing the underlying physics and the analytical image processing techniques. The second part of the book presents in detail a wide variety of applications of these new techniques ranging from mineral identification, mapping of expansive soils, land degradation, agricultural crops, natural vegetation and surface water quality. Additional information on extras.springer.com Sample hyperspectral remote sensing data sets and ENVI viewing software (Freelook) are available on http://extras.springer.com




Leaf Optical Properties


Book Description

Presents state-of-the-art research into leaf interactions with light, for scientists working in remote sensing, plant physiology, ecology and resource management.







Imaging Mass Spectrometry


Book Description

This second edition details new and updated chapters on key methodologies and breakthroughs in the mass spectrometry imaging (MSI) field. Chapters guide readers through nano-Desorption Electrospray Ionisation (nDESI), Matrix Assisted Laser Desorption Ionisation-2 (MALDI-2), Laser Ablation - Inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) ,Imaging Mass Cytometry (IMC) with a variety of diverse samples including eye tissue, crop analysis, 3D cell culture models, and counterfeit goods analysis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Imaging Mass Spectrometry: Methods and Protocols, Second Edition aims to be a useful and practical guide to new researchersand experts looking to expand their knowledge.




Hyperspectral Imaging Remote Sensing


Book Description

Understand the seminal principles, current techniques, and tools of imaging spectroscopy with this self-contained introductory guide.




Transmission Electron Microscopy


Book Description

This text is a companion volume to Transmission Electron Microscopy: A Textbook for Materials Science by Williams and Carter. The aim is to extend the discussion of certain topics that are either rapidly changing at this time or that would benefit from more detailed discussion than space allowed in the primary text. World-renowned researchers have contributed chapters in their area of expertise, and the editors have carefully prepared these chapters to provide a uniform tone and treatment for this exciting material. The book features an unparalleled collection of color figures showcasing the quality and variety of chemical data that can be obtained from today’s instruments, as well as key pitfalls to avoid. As with the previous TEM text, each chapter contains two sets of questions, one for self assessment and a second more suitable for homework assignments. Throughout the book, the style follows that of Williams & Carter even when the subject matter becomes challenging—the aim is always to make the topic understandable by first-year graduate students and others who are working in the field of Materials Science Topics covered include sources, in-situ experiments, electron diffraction, Digital Micrograph, waves and holography, focal-series reconstruction and direct methods, STEM and tomography, energy-filtered TEM (EFTEM) imaging, and spectrum imaging. The range and depth of material makes this companion volume essential reading for the budding microscopist and a key reference for practicing researchers using these and related techniques.




Quantitative Magnetic Resonance Imaging


Book Description

Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches