Immune Hematology


Book Description

This text provides a concise yet comprehensive overview of the most common autoimmune cytopenias affecting adults and children. The book is divided into four sections, each of which focuses on a major autoimmune cytopenia. The first section features background, pathophysiology, presentation, evaluation, and treatment strategies for immune thrombocytopenia (ITP), the most common cause of antibody-mediated platelet destruction. The second section reviews common forms and treatment strategies for autoimmune hemolytic anemia (AIHA), including a chapter dedicated specifically to Evans Syndrome. The third section comprehensively reviews the pathophysiology, diagnosis and current management approaches to thrombotic thrombocytopenic purpura (TTP), a potentially life-threatening autoimmune syndrome. The book concludes with a final section on autoimmune neutropenia. Each section includes a review of common underlying systemic autoimmune conditions and immune deficiency syndromes that can accompany or cause autoimmune cytopenias. Written by experts in each content area, Immune Hematology: Diagnosis and Management of Autoimmune Cytopenias is a valuable resource for clinicians and professionals who treat patients afflicted with autoimmune cytopenias, including primary care providers, hematologist/oncologists, immunologists, among others.




Janeway's Immunobiology


Book Description

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.




Advanced Hematology in Integrated Cardiovascular Chinese Medicine


Book Description

Advanced Hematology in Integrative Cardiovascular Chinese Medicine, volume three in the Integrative Cardiovascular Chinese Medicine series, systematically observes and discusses laboratory tests which detect heart diseases and analyzes the results. It includes coverage of red and white blood cell homeostasis and advanced anatomy and physiology of the vascular system, including the biomedicine perspectives of blood and lymphatic system, and TCM perspectives of essence, qi, blood and body fluid. In addition, the book examines the immune system from the perspective of Traditional Chinese Medicine, including pestilential differentiation. Case studies, lab charts and laboratory differentials according to Chinese and Western medicine perspectives are also included. Finally, the book discusses the use of lab results for assisting and/or confirming diagnoses of blood and cardiovascular disorders in both Traditional Chinese Medicine and Western medicine. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base to guide clinical practice and encourage collaboration. Compares medical theories in Chinese medicine and Western medicine on blood, immune system and cardiovascular diseases Provides laboratory cases, tests and values concerning pathology of the blood and the cardiovascular system necessary for diagnosing and monitoring within integrative cardiovascular Chinese medicine Includes coverage of advanced level blood, complement and immune systems from both Western and Chinese medicine perspectives




Williams Hematology, 9E


Book Description

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2020! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.




Diagnosis of Blood and Bone Marrow Disorders


Book Description

This book focuses on hematopoietic and lymphoid neoplasms that initially present as peripheral blood abnormalities, with either cytopenias or elevated peripheral blood counts, as well as non-neoplastic conditions that may raise concern for a hematologic malignancy. The scope of the book includes myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), mixed myelodysplastic/myeloproliferative neoplasms (MDS/MPN), as well as lymphomas and lymphoid leukemias that typically present initially with peripheral blood abnormalities. Within each category, a comprehensive list of differential diagnoses is discussed. For each disease entity, the reader is updated with new molecular genetic data, biomarkers, and recent applications of immunophenotyping, and how to incorporate the new information in disease diagnosis and classifications is illustrated, including the use of diagnostic algorithms where appropriate. The book employs the revised WHO Classification of Hematopoietic Neoplasms for all disease entities. Diagnosis of Blood and Bone Marrow Disorders will serve as a very useful resource for pathologists, pathologists in training, hematologists and medical technologists who are involved in the clinical work-up of patients with bone marrow and blood neoplasms. It will provide a practical and concise yet comprehensive review.




Mast Cells and Basophils


Book Description

Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.




Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation


Book Description

Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. - Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside - Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios - Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications




Oxford Handbook of General Practice


Book Description

This handbook covers practical issues, such as how to deal with confidentiality, compliance, complaints, and referral letters as well as clinical medicine. It also raises issues such as dealing with stress and entering the profession.




Evidence-Based Management of Sickle Cell Disease


Book Description

Sickle cell disease can be severe and disabling. When properly treated, patients live longer and with better quality life. This is a US government publication intended to provide evidence-based guidelines for the care of these patients for the use of all concerned providers as well as patients and family members. This book is available in print here for convenience.




AACN Core Curriculum for Pediatric High Acuity, Progressive, and Critical Care Nursing


Book Description

AACN Core Curriculum for Pediatric High Acuity, Progressive, and Critical Care, Third Edition, provides content required to deliver the best care for critically ill or injured children. As acuity increases in all inpatient departments and the practice of pediatric critical care expands beyond the acute phase of illness or injury, knowledge of pediatric critical care is more essential than ever. Pediatric acute and critical care nurses find themselves handling not only their patients, but care of their families and management of an interprofessional team of caregivers. With emphasis on evidence-based care and professionalism, this essential resource captures the professional role of the pediatric critical care nurse and the nurse’s contributions to the process of continuous quality improvement. Ideal for pediatric critical care and acute care nurses, high acuity/critical care courses, and continuing education, AACN Core Curriculum for Pediatric High Acuity, Progressive, and Critical Care, Third Edition, contains core AACN guidelines for the highest quality nursing practice. The text covers anatomic, physiologic, cognitive, and psychosocial changes that occur throughout the pediatric lifespan. Chapters are systems focused and review developmental anatomy and physiology, clinical assessment, pharmacology, diagnostic tests, and therapeutic procedures. For each type of disease and injury, information is provided on pathophysiology, etiology, risk factors, signs and symptoms, nursing and collaborative interprofessional management, and complications. New to the Third Edition: Updated to include current patient management and the latest pediatric drug information Contains a completely new chapter on professional nursing issues, including quality, safety, communications, teamwork, work environment, and personal wellness Provides revised case studies and review questions/answers reflecting the latest version of the CCRN® Pediatric exam Key Features: Delivers comprehensive, current information for nursing students and those preparing for the CCRN® Pediatric exam Content is based on the most current standards of care, scope of practice, national guidelines, key AACN initiatives, and the AACN Certification Corporation Pediatric CCRN® Test Plan Presented in easy-to-read outline format for quick access to information Written and endorsed by AACN and AACN-affiliated subject matter experts Provides case studies to illustrate patient scenarios Discusses the application of AACN’s Synergy Model for Patient Care in pediatric high acuity and critical care nursing practice Includes in-depth coverage of multisystem problems such as multiple trauma, toxicology, septic shock, and burns