Molecular Evolution and Protobiology


Book Description

In recent years, an ever-increasing amount of research has been conducted on the physico-chemical basis of the origin and evolution of life, or protobiology. Many questions are raised in this endeavor: What research methodology should be employed? What sort of dependable facts are available as a firm frame of reference upon which the physico-chemical origin of life or protolife could be examined? Is the origin due exclusively to chance events? If not, what is then responsible for the origin? What physical reality underlies the evolutionarily selective process leading to the origin? What role does variation assume and how is it generated in the course of evolution? Many research workers have pursued various avenues toward answering the stated questions. Among them, we believe Sidney W. Fox has been playing a very unique and pivotal role over the past quarter of a century, presiding over 240 man-years or more of labo ratory work. His laboratory syntheses of thermal proteins called proteinoids and proteinoid micro spheres have emphasized the prin ciple of the self-sequencing of amino acids as a key concept of protobiological synthesis. The significance of his contribution is seen in presenting the experimental evidence that the origin of life is largely due to nonrandom events. This discovery marks a new epoch in the conceptual development of studying the origin of life by focusing on the molecular processes that underlied the emergence and evolution of protobiological information.




Route log and finder list


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EDA Directory of Approved Projects


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The Bridges Of Madison County


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Fall in love with one of the bestselling novels of all time -- the legendary love story that became a beloved film starring Clint Eastwood and Meryl Streep. If you've ever experienced the one true love of your life, a love that for some reason could never be, you will understand why readers all over the world are so moved by this small, unknown first novel that they became a publishing phenomenon and #1 bestseller. The story of Robert Kincaid, the photographer and free spirit searching for the covered bridges of Madison County, and Francesca Johnson, the farm wife waiting for the fulfillment of a girlhood dream, The Bridges of Madison County gives voice to the longings of men and women everywhere -- and shows us what it is to love and be loved so intensely that life is never the same again.




Oklahoma Session Laws


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How to House the Homeless


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How to House the Homeless, editors Ingrid Gould Ellen and Brendan O'Flaherty propose that the answers entail rethinking how housing markets operate and developing more efficient interventions in existing service programs. The book critically reassesses where we are now, analyzes the most promising policies and programs going forward, and offers a new agenda for future research. How to House the Homeless makes clear the inextricable link between homelessness and housing policy. Contributor Jill Khadduri reviews the current residential services system and housing subsidy programs. For the chronically homeless, she argues, a combination of assisted housing approaches can reach the greatest number of people and, specifically, an expanded Housing Choice Voucher system structured by location, income, and housing type can more efficiently reach people at-risk of becoming homeless and reduce time spent homeless. Robert Rosenheck examines the options available to homeless people with mental health problems and reviews the cost-effectiveness of five service models: system integration, supported housing, clinical case management, benefits outreach, and supported employment. He finds that only programs that subsidize housing make a noticeable dent in homelessness, and that no one program shows significant benefits in multiple domains of life. Contributor Sam Tsemberis assesses the development and cost-effectiveness of the Housing First program, which serves mentally ill homeless people in more than four hundred cities. He asserts that the program's high housing retention rate and general effectiveness make it a viable candidate for replication across the country. Steven Raphael makes the case for a strong link between homelessness and local housing market regulations—which affect housing affordability—and shows that the problem is more prevalent in markets with stricter zoning laws. Finally, Brendan O'Flaherty bridges the theoretical gap between the worlds of public health and housing research, evaluating the pros and cons of subsidized housing programs and the economics at work in the rental housing market and home ownership. Ultimately, he suggests, the most viable strategies will serve as safety nets—"social insurance"—to reach people who are homeless now and to prevent homelessness in the future. It is crucial that the links between effective policy and the whole cycle of homelessness—life conditions, service systems, and housing markets—be made clear now. With a keen eye on the big picture of housing policy, How to House the Homeless shows what works and what doesn't in reducing the numbers of homeless and reaching those most at risk.