Forgotten People, Forgotten Diseases


Book Description

Forgotten People, Forgotten Diseases Second Edition The neglected tropical diseases (NTDs) are the most common infections of the world's poor, but few people know about these diseases and why they are so important. This second edition of Forgotten People, Forgotten Diseases provides an overview of the NTDs and how they devastate the poor, essentially trapping them in a vicious cycle of extreme poverty by preventing them from working or attaining their full intellectual and cognitive development. Author Peter J. Hotez highlights a new opportunity to control and perhaps eliminate these ancient scourges, through alliances between nongovernmental development organizations and private-public partnerships to create a successful environment for mass drug administration and product development activities. Forgotten People, Forgotten Diseases also Addresses the myriad changes that have occurred in the field since the previous edition. Describes how NTDs have affected impoverished populations for centuries, changing world history. Considers the future impact of alliances between nongovernmental development organizations and private-public partnerships. Forgotten People, Forgotten Diseases is an essential resource for anyone seeking a roadmap to coordinate global advocacy and mobilization of resources to combat NTDs.




Neglected Tropical Diseases - Sub-Saharan Africa


Book Description

This book provides an overview on the major neglected tropical diseases (NTDs) occurring in Sub-Saharan Africa, such as Leishmaniasis, Buruli Ulcer and Schistosomiasis. In well-structured chapters epidemiology and biology of these parasitic diseases will be discussed in detail. Further, diagnostics and therapeutic approaches as well as prevention strategies will be reviewed. The book will be of interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of the Sub-Saharan region.




Helminth Control in School-Age Children


Book Description

More than 2000 million people worldwide are affected by schistosomiasis and soil-transmitted helminth (STH) infections and 155 000 deaths are reported each year. These infections are diseases associated with poverty, and in school-age populations in developing countries, intestinal helminth infections rank first among the causes of all communicable and noncommunicable diseases. This book describes a cost-effective approach to the control of these infections, based on the use of periodic parasitological surveys of school population samples. It is intended as a guide for health education managers responsible for implementing community-based programmes.




Human Schistosomiasis


Book Description

Human schistosomes (blood flukes) are digenetic trematodes that spend the adult part of their life cycle in humans and a further part in aquatic snails. Despite advances in chemotherapy, schistosomiasis is still a significant infection in the populations of several countries in the tropics. This book replaces a previous volume Schistosomiasis: Epidemiology, Treatment and Control (Heinemann, 1982) by Jordan and Webbe. All chapters have been rewritten by internationally renowned workers. Ultrasound, expected to aid identification of early disease in the field and increase our understanding of its evolution, is discussed in a new chapter. Others, each with an extensive bibliography, review the parasites and their snail intermediate hosts, epidemiology, clinical manifestations and pathology, diagnosis, immunology, drugs and patient management and control. Limitations of the role of chemotherapy in morbidity control are discussed and the need for flexibility in control interventions in the varied epidemiological situations is stressed. An interdisciplinary approach may be necessary to reduce transmission by appropriate measures against the snail intermediate host, and to implement public health measures, including the provision of safe water (with many other medical and social benefits) and health education. This comprehensive volume is for public health workers involved in the prevention and control of the disease, for physicians, and for students and teachers of many disciplines. It also provides a reference book for health planners, social anthropologists, health educators, water and sanitary engineers and others engaged in improving health in the tropics. Physicians in temperate countries will also find it a useful reference book as schistosomiasis, often acute, is being diagnosed more frequently in those returning from holidays in endemic areas.




The Control of Schistosomiasis


Book Description

A comprehensive guide to the technical and practical factors that need to be considered when designing and implementing programmes for the control of schistosomiasis. Noting the success of strategies focused on morbidity control, the report shows how the spectrum of programme goals can now be broadened to include reductions in the prevalence and intensity of established infections and decreases in the intensity of transmission. Throughout, emphasis is placed on knowledge and experiences that can help programme managers establish feasible goals and then select control options in line with the form of infection, its public health importance, the degree and type of morbidity, available resources, and integration into the primary health care system. Information is specific to the different types of schistosomiasis and the distinctive epidemiological features, clinical manifestations, and response to treatment of each. The report has three main parts. The first, which is devoted to strategies for control, gives programme managers a concise, yet complete review of all factors that need to be considered when establishing priorities and deciding on the most appropriate options for control. Emphasis is placed on the many recent advances, including experiences with praziquantel, that have strengthened the tools available for prevention, diagnosis, treatment, and cure. While noting the severe financial constraints faced in many endemic countries, the report cites recent findings and experiences that make it possible for each endemic country to take action against schistosomiasis, even when resources are scarce and health services limited. The second part gives specialists a detailed state-of-the-art review of all technical developments relevant to control. Separate sections describe the distinctive patterns of morbidity and mortality seen in each form of infection, update knowledge about the parasite and its mammalian hosts, and summarize what is known about the snail intermediate host and its susceptibility to control by molluscicides, biological agents, and environmental management. Other sections describe a range of advances in diagnostic tools, from hospital-based radiological investigations to the use of portable ultrasound equipment at the village level, and issue advice on treatmet and retreatment schedules for chemotherapy with praziquantel, metrifonate, and oxamniquine. The final part uses profiles of control programmes in 23 countries to document the feasibility of control and illustrate the diversity of approaches that can be applied according to different national conditions, forms and prevalence of infection, health care systems, and available resources.




Preventive Chemotherapy in Human Helminthiasis


Book Description

This manual focuses on how and when a set of low-cost or free drugs should be used in developing countries to control a set of diseases caused by worm infections. Preventive chemotherapy in this context means using drugs that are effective against a broad range of worm infections to simultaneously treat the four most common diseases caused by worms: river blindness (onchocerciasis), elephantiasis (lymphatic filariasis), schistosomiasis, and soil-transmitted helminthiasis. Significant opportunities also exist to integrate these efforts with the prevention and control of diseases such as trachoma. The new approach provides a critical first step in combining treatment regimens for diseases which, although different in themselves, require common resources and delivery strategies for control or elimination.




Schistosomiasis


Book Description

Schistosomiasis is a disease affecting over 200 million people in developing countries. It is caused by worms that need particular species of fresh water snails for completing their life cycle, and developments in Third World countries have spread and increased the severity of the disease. Dr Jordan describes a 15 year study on St Lucia, a mountainous Caribbean Island where isolated valleys provided ideal field laboratories for comparing the effects on transmission, the advantages and disadvantages of intensive snail control, environmental improvement (providing villages with water), and chemotherapy with newly available drugs. The project was staffed by a multidisciplinary team and their intensive programme led to successful control. This book describes the investigation, fully and readably. It will be valuable to all who work in the fields of tropical medicine, parasitology, epidemiology, community and environmental health, and vital to workers on schistosomiasis control in developing countries.




Parasitic Diseases


Book Description

Reports on schistosomiasis epidemiology and clinical features in Africa and Brazil, and development of novel drugs that affect the worm tegument, and vaccine based on excretory-secretory products and Type 2 cytokines.




In Her Lifetime


Book Description

The relative lack of information on determinants of disease, disability, and death at major stages of a woman's lifespan and the excess morbidity and premature mortality that this engenders has important adverse social and economic ramifications, not only for Sub-Saharan Africa, but also for other regions of the world as well. Women bear much of the weight of world production in both traditional and modern industries. In Sub-Saharan Africa, for example, women contribute approximately 60 to 80 percent of agricultural labor. Worldwide, it is estimated that women are the sole supporters in 18 to 30 percent of all families, and that their financial contribution in the remainder of families is substantial and often crucial. This book provides a solid documentary base that can be used to develop an agenda to guide research and health policy formulation on female health--both for Sub-Saharan Africa and for other regions of the developing world. This book could also help facilitate ongoing, collaboration between African researchers on women's health and their U.S. colleagues. Chapters cover such topics as demographics, nutritional status, obstetric morbidity and mortality, mental health problems, and sexually transmitted diseases, including HIV.