Infrared and Raman Spectroscopy of Biological Materials


Book Description

Infrared and Raman Spectroscopy of Biological Materials facilitates a comprehensive and through understanding of the latest developments in vibrational spectroscopy. It contains explains key breakthroughs in the methodologies and techniques for infrared, near-infrared, and Raman spectroscopy. Topics include qualitative and quantitative analysis, biomedical applications, vibrational studies of enzymatic catalysis, and chemometrics.




The Handbook of Infrared and Raman Characteristic Frequencies of Organic Molecules


Book Description

This necessary desk reference for every practicing spectroscopist represents the first definitive book written specifically to integrate knowledge about group frequencies in infrared as well as Raman spectra. In the spirit of previous classics developed by Bellamy and others, this volume has expanded its scope and updated its coverage. In addition to detailing characteristic group frequencies of compounds from a comprehensive assortment of categories, the book includes a collection of spectra and a literature search conducted to verify existing correlations and to determine ways to enhance correlations between vibrational frequencies and molecular structure. Particular attention has been given to the correlation between Raman characteristic frequencies and molecular structure. - Constitutes a necessary reference for every practicing vibrational spectroscopist - Provides the new definitive text on characteristic frequencies of organic molecules - Incorporates group frequencies for both infrared and Raman spectra - Details the characteristic IR and Raman frequencies of compounds in more than twenty major categories - Includes an extensive collection of spectra - Compiled by internationally recognized experts




Infrared and Raman Spectroscopy of Biological Molecules


Book Description

For this summer school in Athens, Greece, August 22-21, 1978, I took as my objective the presentation of a timely representative account of the application of infrared and Raman spectro scopy to biological molecules. A summer school is made up of a number of things -ideas, people, organization international collaboration and sponsorship. The exchange of ideas the student-lecturer interaction in the discussion periods and the tutorials satisfy the urgent need of all the participants to meet and discuss topics of current scientific interest. It seems therefore appropriate to publish this summer school proceedings in order to make it a lasting event and that appreciation be shown to those people and institutions that made it all possible. The summer school was held under the auspices of the Greek Ministry of Culture and Sciences under the sponsorship of the NATO Scientific Affairs Division in Brussels. In addition, support was provided by the National Hellenic Research Foundation and the Ministry of Culture and Sciences for several social and scientific functions.




Infrared and Raman Spectroscopy


Book Description

Infrared and Raman Spectroscopy, Principles and Spectral Interpretation, Second Edition provides a solid introduction to vibrational spectroscopy with an emphasis on developing critical interpretation skills. This book fully integrates the use of both IR and Raman spectroscopy as spectral interpretation tools, enabling the user to utilize the strength of both techniques while also recognizing their weaknesses. This second edition more than doubles the amount of interpreted IR and Raman spectra standards and spectral unknowns. The chapter on characteristic group frequencies is expanded to include increased discussions of sulphur and phosphorus organics, aromatic and heteroaromatics as well as inorganic compounds. New topics include a discussion of crystal lattice vibrations (low frequency/THz), confocal Raman microscopy, spatial resolution in IR and Raman microscopy, as well as criteria for selecting Raman excitation wavelengths. These additions accommodate the growing use of vibrational spectroscopy for process analytical monitoring, nanomaterial investigations, and structural and identity determinations to an increasing user base in both industry and academia. - Integrates discussion of IR and Raman spectra - Pairs generalized IR and Raman spectra of functional groups with tables and text - Includes over 150 fully interpreted, high quality IR and Raman reference spectra - Contains fifty-four unknown IR and Raman spectra, with a corresponding answer key




Vibrational Spectroscopy in Life Science


Book Description

The authors describe basic theoretical concepts of vibrational spectroscopy, address instrumental aspects and experimental procedures, and discuss experimental and theoretical methods for interpreting vibrational spectra. It is shown how vibrational spectroscopy provides information on general aspects of proteins, such as structure, dynamics, and protein folding. In addition, the authors use selected examples to demonstrate the application of Raman and IR spectroscopy to specific biological systems, such as metalloproteins, and photoreceptors. Throughout, references to extensive mathematical and physical aspects, involved biochemical features, and aspects of molecular biology are set in boxes for easier reading. Ideal for undergraduate as well as graduate students of biology, biochemistry, chemistry, and physics looking for a compact introduction to this field.




Applications of Raman Spectroscopy to Biology


Book Description

Raman spectroscopy has been known and used as a technique for 80 years, originally for the study of inorganic substances. Recent advances in underlying technology, such as lasers, detectors, filters and components, have transformed the technique into a very effective modern tool for studying complex biological problems. Professor Mahmoud Ghomi (of the University of Paris XIII) has edited this book on the applications of Raman spectroscopy to biology, covering in a readily accessible way the area from basic studies to the diagnosis of disease. The early chapters provide background information on basic principles underlying the main Raman methods covered in the book, with information on Surface-Enhanced Raman Scattering (SERS) and Surface-Enhanced Fluorescence (SEF), as well as giving accounts of applications to biomolecular and cellular investigations. Among the topics covered are studies of drugs and their complexes with biomolecules on nanoparticles, application of SERS to blood analysis, studies of single cells and of applications to human cancer diagnostics.This will be a useful book for experimental scientists in academic, governmental, industrial and clinical environments and for those entering the field of biomolecular spectroscopy.




Ultrafast Infrared Vibrational Spectroscopy


Book Description

The advent of laser-based sources of ultrafast infrared pulses has extended the study of very fast molecular dynamics to the observation of processes manifested through their effects on the vibrations of molecules. In addition, non-linear infrared spectroscopic techniques make it possible to examine intra- and intermolecular interactions and how such interactions evolve on very fast time scales, but also in some instances on very slow time scales. Ultrafast Infrared Vibrational Spectroscopy is an advanced overview of the field of ultrafast infrared vibrational spectroscopy based on the scientific research of the leading figures in the field. The book discusses experimental and theoretical topics reflecting the latest accomplishments and understanding of ultrafast infrared vibrational spectroscopy. Each chapter provides background, details of methods, and explication of a topic of current research interest. Experimental and theoretical studies cover topics as diverse as the dynamics of water and the dynamics and structure of biological molecules. Methods covered include vibrational echo chemical exchange spectroscopy, IR-Raman spectroscopy, time resolved sum frequency generation, and 2D IR spectroscopy. Edited by a recognized leader in the field and with contributions from top researchers, including experimentalists and theoreticians, this book presents the latest research methods and results. It will serve as an excellent resource for those new to the field, experts in the field, and individuals who want to gain an understanding of particular methods and research topics.




Infrared and Raman Spectroscopy


Book Description




Vibrational Spectroscopy for Tissue Analysis


Book Description

A rapidly growing field, vibrational spectroscopy has found applications in industries including pharmaceutical manufacture, food and drug safety, and process monitoring on production lines. In particular, interest in clinical spectroscopy is rising rapidly as researchers recognize the potential of the vibrational spectroscopic techniques—Infrared (IR) and Raman Spectroscopy—as noninvasive tissue diagnosis tools. However, the details of the characteristic peak frequencies and their relationship to specific functional groups present in the biological tissues have not been fully understood. Vibrational Spectroscopy for Tissue Analysis introduces IR and Raman Spectroscopy to those scientists who are either using these spectroscopic techniques to address clinical problems or planning to use spectroscopy to analyze clinical tissues and understand their chemical composition. By compiling the interpretations and understandings of the spectral peaks of the biological molecules in one place, this book aids in the understanding of IR and Raman Spectroscopy, and what these techniques can offer both in early diagnosis of the disease and monitoring of the progression of the disease. Despite the tremendous advances in the field of spectroscopy, where new applications are emerging at the pace of development, there are still areas of research that are crying for further exploration. This book bridges the gap between the spectroscopic research and medical applications.