Insights in Computational Genomics: 2022


Book Description

This Research Topic is part of the Insights in Frontiers in Genetics series. Other titles in the series are: Genetics, Insights in Evolutionary and Population Genetics: 2022 Genetics, Insights in Livestock Genomics: 2022 Genetics, Insights in Epigenomics and Epigenetics: 2022 Genetics, Insights in Behavioral and Psychiatric Genetics: 2022 Genetics, Insights in Neurogenomics: 2022 Genetics, Insights in Genomic Assay Technology: 2022 Genetics, Insights in Genetics of Common and Rare Diseases: 2022 We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Genetics. Frontiers have organized a series of Research Topics to highlight the latest advancements in research across the field of Computational Genomics, with articles from the members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Prof Richard Emes, Specialty Chief Editor of the Computational Genomics section, together with Dr. Pirooznia and Dr Zou, focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Computational Genomics. The Research Topic solicits brief, forward-looking contributions from the editorial board members that describe the state of the art, outlining recent developments and major accomplishments that have been achieved and that need to occur to move the field forward. Authors are encouraged to identify the greatest challenges in the sub-disciplines, and how to address those challenges.










Multi-omics and Computational Biology in Horticultural Plants: From Genotype to Phenotype, Volume II


Book Description

This Research Topic is part of the article collection series - Multi-omics and Computational Biology in Horticultural Plants: From Genotype to Phenotype. Horticultural plants play an important role for humans by providing herbal medicines, beverages, vegetables, fruits, and ornamentals. High-throughput technologies have revolutionised the time scale and power of detecting insights into physiological changes and biological mechanisms in plants. All sequencing data and tools have helped us better understand the evolutionary histories of horticultural plants and provide genotype and phenotype resources for molecular studies on economically important traits. The integration of these -omics technologies (e.g., genomics, transcriptomics, proteomics, metabolomics, lipidomics, ionomics, and redoxomics) is currently at the forefront of plant research. The genomes of horticultural plants are highly diverse and complex, often with a high degree of heterozygosity and polyploidy. Novel computational methods need to be developed to take advantage of state-of-the-art genomic technologies. As a result, the mining of multi-omics data and the development of new computational biology approaches for the reliable and efficient analysis of plant traits is necessary.




Computational Biology for Stem Cell Research


Book Description

Computational Biology for Stem Cell Research is an invaluable guide for researchers as they explore HSCs and MSCs in computational biology. With the growing advancement of technology in the field of biomedical sciences, computational approaches have reduced the financial and experimental burden of the experimental process. In the shortest span, it has established itself as an integral component of any biological research activity. HSC informatics (in silico) techniques such as machine learning, genome network analysis, data mining, complex genome structures, docking, system biology, mathematical modeling, programming (R, Python, Perl, etc.) help to analyze, visualize, network constructions, and protein-ligand or protein-protein interactions. This book is aimed at beginners with an exact correlation between the biomedical sciences and in silico computational methods for HSCs transplantation and translational research and provides insights into methods targeting HSCs properties like proliferation, self-renewal, differentiation, and apoptosis. - Modeling Stem Cell Behavior: Explore stem cell behavior through animal models, bridging laboratory studies to real-world clinical allogeneic HSC transplantation (HSCT) scenarios. - Bioinformatics-Driven Translational Research: Navigate a path from bench to bedside with cutting-edge bioinformatics approaches, translating computational insights into tangible advancements in stem cell research and medical applications. - Interdisciplinary Resource: Discover a single comprehensive resource catering to biomedical sciences, life sciences, and chemistry fields, offering essential insights into computational tools vital for modern research.







Methods in computational genomics


Book Description




Bioinformatics and Computational Biology


Book Description

Bioinformatics and Computational Biology: Technological Advancements, Applications and Opportunities is an invaluable resource for general and applied researchers who analyze biological data that is generated, at an unprecedented rate, at the global level. After careful evaluation of the requirements for current trends in bioinformatics and computational biology, it is anticipated that the book will provide an insightful resource to the academic and scientific community. Through a myriad of computational resources, algorithms, and methods, it equips readers with the confidence to both analyze biological data and estimate predictions. The book offers comprehensive coverage of the most essential and emerging topics: Cloud-based monitoring of bioinformatics multivariate data with cloud platforms Machine learning and deep learning in bioinformatics Quantum machine learning for biological applications Integrating machine learning strategies with multiomics to augment prognosis in chronic diseases Biomedical engineering Next generation sequencing techniques and applications Computational systems biology and molecular evolution While other books may touch on some of the same issues and nuances of biological data analysis, they neglect to feature bioinformatics and computational biology exclusively, and as exhaustively. This book's abundance of several subtopics related to almost all of the regulatory activities of biomolecules from where real data is being generated brings an added dimension.