Instrumental Methods of Analysis


Book Description

Instrumental Methods of Analysis is a textbook designed to introduce various analytical and chemical methods, their underlying principles and applications to the undergraduate engineering students of biotechnology and chemical engineering. This book would also be of interest to students who pursue their B. Sc / M. Sc degree programs in biotechnology and chemistry.







Analytical Biotechnology


Book Description

ANABIOTEC '92 focused on the further integration of biotechnology and analytical chemistry. The results of this symposium clearly demonstrated that a substantial progress could be reported in the application of both conventional and new analytical techniques, the latter essentially based on natural analytical tools such as biomolecules. The main themes covered during this meeting are fermentation monitoring, chromatography, instrumental analysis, biosensors and bioanalysis.




Instrumental Methods in Metal Ion Speciation


Book Description

The knowledge of metal ion speciation is essential for predicting the exact toxicities of metal ion species in the environment. Metal ions can exist in various oxidation states, each of which possesses different physical and chemical properties as well as exhibit varying toxicities. Often, toxicity data is unreliable because it is based on metal io




Instrumental Methods of Analysis


Book Description

The book is designed to introduce the recent developments and changes of various analytical techniques their underlying principles instrumentations and applications. It comprehensively covers fundamental information and applications of analytical techniques and provides precise sketches and flow sheets to understand the analytical techniques obviously and discusses different techniques such as microscopy centrifugation spectroscopy chromatography.This book also explains the functional aspects of all instruments to provide working knowledge of their instrumentation principle and applications. It provides an understanding of analytical techniques for all undergraduate and postgraduate students of biotechnology chemical engineering pharmacy biochemistry microbiology and chemistry teaching and academic research.




Practical Instrumental Analysis


Book Description

This practical book in instrumental analytics conveys an overview of important methods of analysis and enables the reader to realistically learn the (principally technology-independent) working techniques the analytical chemist uses to develop methods and conduct validation. What is to be conveyed to the student is the fact that analysts in their capacity as problem-solvers perform services for certain groups of customers, i.e., the solution to the problem should in any case be processed in such a way as to be "fit for purpose". The book presents sixteen experiments in analytical chemistry laboratory courses. They consist of the classical curriculum used at universities and universities of applied sciences with chromatographic procedures, atom spectrometric methods, sensors and special methods (e.g. field flow fractionation, flow injection analysis and N-determination according to Kjeldahl). The carefully chosen combination of theoretical description of the methods of analysis and the detailed instructions given are what characterizes this book. The instructions to the experiments are so detailed that the measurements can, for the most part, be taken without the help of additional literature. The book is complemented with tips for effective literature and database research on the topics of organization and the practical workflow of experiments in analytical laboratory, on the topic of the use of laboratory logs as well as on writing technical reports and grading them (Evaluation Guidelines for Laboratory Experiments). A small introduction to Quality Management, a brief glance at the history of analytical chemistry as well as a detailed appendix on the topic of safety in analytical laboratories and a short introduction to the new system of grading and marking chemicals using the "Globally Harmonized System of Classification and Labelling of Chemicals (GHS)", round off this book. This book is therefore an indispensable workbook for students, internship assistants and lecturers (in the area of chemistry, biotechnology, food technology and environmental technology) in the basic training program of analytics at universities and universities of applied sciences.




Bioanalytics


Book Description

Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids. The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a bird's eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. The following techniques are covered in detail: - Purification and determination of proteins - Measuring enzymatic activity - Microcalorimetry - Immunoassays, affinity chromatography and other immunological methods - Cross-linking, cleavage, and chemical modification of proteins - Light microscopy, electron microscopy and atomic force microscopy - Chromatographic and electrophoretic techniques - Protein sequence and composition analysis - Mass spectrometry methods - Measuring protein-protein interactions - Biosensors - NMR and EPR of biomolecules - Electron microscopy and X-ray structure analysis - Carbohydrate and lipid analysis - Analysis of posttranslational modifications - Isolation and determination of nucleic acids - DNA hybridization techniques - Polymerase chain reaction techniques - Protein sequence and composition analysis - DNA sequence and epigenetic modification analysis - Analysis of protein-nucleic acid interactions - Analysis of sequence data - Proteomics, metabolomics, peptidomics and toponomics - Chemical biology




Biotechnology and Pharmacy


Book Description

Biotechnology and Pharmacy offers a unique overview of the principles of biotechnology and their applications in the pharmaceutical sciences. The book assumes a basic knowledge of biology and chemistry and was written as a text suitable for students of pharmacy or other health sciences. The first part of the book describes the basic elements of biotechnology, such as recombinant DNA and monoclonal antibody technology; the second part comprehensively covers applications of biotechnology in the diagnosis and treatment of disease; and the final part offers a practical discussion of how biotechnology products will affect the practice of pharmacy. Microbiologists, biochemists, and medicinal chemists will also find this book to be a valuable reference.




Analytical Techniques in the Pharmaceutical Sciences


Book Description

The aim of this book is to present a range of analytical methods that can be used in formulation design and development and focus on how these systems can be applied to understand formulation components and the dosage form these build. To effectively design and exploit drug delivery systems, the underlying characteristic of a dosage form must be understood--from the characteristics of the individual formulation components, to how they act and interact within the formulation, and finally, to how this formulation responds in different biological environments. To achieve this, there is a wide range of analytical techniques that can be adopted to understand and elucidate the mechanics of drug delivery and drug formulation. Such methods include e.g. spectroscopic analysis, diffractometric analysis, thermal investigations, surface analytical techniques, particle size analysis, rheological techniques, methods to characterize drug stability and release, and biological analysis in appropriate cell and animal models. Whilst each of these methods can encompass a full research area in their own right, formulation scientists must be able to effectively apply these methods to the delivery system they are considering. The information in this book is designed to support researchers in their ability to fully characterize and analyze a range of delivery systems, using an appropriate selection of analytical techniques. Due to its consideration of regulatory approval, this book will also be suitable for industrial researchers both at early stage up to pre-clinical research.