Insulin - the Crooked Timber


Book Description

Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. To mark the centenary of this landmark in medicine, this book charts the journey of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, and which earned the founders of US biotech company Genentech a small fortune. Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, Insulin - The Crooked Timber reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes and heroines. It discusses in detail the circumstances of Canadian scientist Frederick Banting whose award of the 1923 Nobel Prize for this life-saving discovery proved to be both a blessing and a curse for him and explores how the human story behind this discovery still remains one of ongoing political and scientific controversy. The book is the result of the author's own shocking diagnosis with Type 1 diabetes and its story reminds us all of what technology can - and cannot do - for us. As the world struggles to emerge from the COVID-19 pandemic and face future challenges such as climate change, the lessons that we can learn from the story of insulin have never been more important.




Freedom From the Market


Book Description

The progressive economics writer redefines the national conversation about American freedom “Mike Konczal [is] one of our most powerful advocates of financial reform‚ [a] heroic critic of austerity‚ and a huge resource for progressives.”—Paul Krugman Health insurance, student loan debt, retirement security, child care, work-life balance, access to home ownership—these are the issues driving America’s current political debates. And they are all linked, as this brilliant and timely book reveals, by a single question: should we allow the free market to determine our lives? In the tradition of Naomi Klein’s The Shock Doctrine, noted economic commentator Mike Konczal answers this question with a resounding no. Freedom from the Market blends passionate political argument and a bold new take on American history to reveal that, from the earliest days of the republic, Americans have defined freedom as what we keep free from the control of the market. With chapters on the history of the Homestead Act and land ownership, the eight-hour work day and free time, social insurance and Social Security, World War II day cares, Medicare and desegregation, free public colleges, intellectual property, and the public corporation, Konczal shows how citizens have fought to ensure that everyone has access to the conditions that make us free. At a time when millions of Americans—and more and more politicians—are questioning the unregulated free market, Freedom from the Market offers a new narrative, and new intellectual ammunition, for the fight that lies ahead.




The Discovery of Insulin


Book Description

The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.




The Man in the Monkeynut Coat


Book Description

Tells the story of the English physicist and molecular biologist William T. Astbury and how his work forms a previously untold chapter in the story of the discovery of the structure of DNA.




Breakthrough


Book Description

An “inspirational” account of how a young girl plight’s “launched a boon for diabetics the world over . . . A remarkable story . . . worthy reading” (Booklist). It is 1919 and Elizabeth Hughes, the eleven-year-old daughter of America’s most-distinguished jurist and politician, Charles Evans HugheAs, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatment—starvation—whittles her down to forty-five pounds of skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases—a miracle soon marred by scientific jealousy, intense business competition and fistfights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injections—all while its discoverers and a little known pharmaceutical company struggle to make it available to the rest of the world. Relive the heartwarming true story of the discovery of insulin as it’s never been told before. Written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly himself, among many others. “[A] fascinating tale of Nobel Prize–winning research. . . . This book is an important read for anyone with diabetes. It is an enjoyable read for those who love mystery and human drama.” —Kenneth T. Jackson, Barzun Professor of History, Columbia University




Polio Wars


Book Description

A study of Australian nurse Sister Elizabeth Kenny and her efforts to have her unorthodox methods of treating polio accepted as mainstream polio care in the United States during the 1940s. A case study of changing clinical care, and an examination of the hidden politics of philanthropies and medical societies.




Last Best Gifts


Book Description

More than any other altruistic gesture, blood and organ donation exemplifies the true spirit of self-sacrifice. Donors literally give of themselves for no reward so that the life of an individual—often anonymous—may be spared. But as the demand for blood and organs has grown, the value of a system that depends solely on gifts has been called into question, and the possibility has surfaced that donors might be supplemented or replaced by paid suppliers. Last Best Gifts offers a fresh perspective on this ethical dilemma by examining the social organization of blood and organ donation in Europe and the United States. Gifts of blood and organs are not given everywhere in the same way or to the same extent—contrasts that allow Kieran Healy to uncover the pivotal role that institutions play in fashioning the contexts for donations. Procurement organizations, he shows, sustain altruism by providing opportunities to give and by producing public accounts of what giving means. In the end, Healy suggests, successful systems rest on the fairness of the exchange, rather than the purity of a donor’s altruism or the size of a financial incentive.




Hoosiers and the American Story


Book Description

A supplemental textbook for middle and high school students, Hoosiers and the American Story provides intimate views of individuals and places in Indiana set within themes from American history. During the frontier days when Americans battled with and exiled native peoples from the East, Indiana was on the leading edge of America’s westward expansion. As waves of immigrants swept across the Appalachians and eastern waterways, Indiana became established as both a crossroads and as a vital part of Middle America. Indiana’s stories illuminate the history of American agriculture, wars, industrialization, ethnic conflicts, technological improvements, political battles, transportation networks, economic shifts, social welfare initiatives, and more. In so doing, they elucidate large national issues so that students can relate personally to the ideas and events that comprise American history. At the same time, the stories shed light on what it means to be a Hoosier, today and in the past.




The Artistry of the Homeric Simile


Book Description

An examination of the aesthetic qualities of the Homeric simile




Forestry Economics


Book Description

Forestry Economics introduces students and practitioners to all aspects of the management and economics of forestry. The book adopts the approach of managerial economics textbooks and applies this to the unique processes and problems faced by managers of forests. While most forestry economics books are written by economists for future economists, what many future forest and natural resource managers need is to understand what economic information is and how to use it to make better business and management decisions. John E. Wagner draws on his twenty years of experience teaching and working in the field of forest resource economics to present students with an accessible understanding of the unique production processes and problems faced by forest and other natural resource managers. There are three unique features of this book: The first is its organization. The material is organized around two common economic models used in forest and natural resources management decision making. The second is the use of case studies from various disciplines: Outdoor and Commercial Recreation, Wood Products Engineering, Forest Products, and Forestry. The purpose of these case studies is to provide students with applications of the concepts being discussed within the text. The third is revisiting the question of how to use economic information to make better business decisions at the end of each chapter. This ties each chapter to the preceding ones and reinforces the hypothesis that a solid working knowledge of these economic models and the information they contain are necessary for making better business decisions. This textbook is an invaluable source of clear and accessible information on forestry economics and management for not only economics students, but for students of other disciplines and those already working in forestry and natural resources.