Use of Laboratory Animals in Biomedical and Behavioral Research


Book Description

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.




Invertebrate Models for Biomedical Research


Book Description

On August 21-26, 1977, two symposia were included in the program of the 10th Annual Meeting of the Society for Invertebrate Pathology held at Michigan State University, East Lansing, Michigan. One was entitled "Invertebrate Models for Biomedical Research" organized by Dr. Thomas C. Cheng, and the second, organized by Dr. Robert S. Anderson, was entitled "Cellular and Humoral Reactions to Disease by Invertebrate Animals." When the final manuscripts of the speakers were received, it became apparent that all of the papers were so closely related that the editors decided that they should be combined and published in a single volume of Comparative Pathobiology under the subtitle of Invertebrate Models for Biomedical Research. This volume is the result. We hope that volume four will provide the reader further insight into the complexity and comprehensiveness of pathobiology. Pathobiology encompasses not only the study of pathologic conditions but also the biology of causative agents and response reactions.




Invertebrate Tissue Culture


Book Description




Biomedical Models and Resources


Book Description

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The Welfare of Invertebrate Animals


Book Description

This book is devoted to the welfare of invertebrates, which make up 99% of animal species on earth. Addressing animal welfare, we do not often think of invertebrates; in fact we seldom consider them to be deserving of welfare evaluation. And yet we should. Welfare is a broad concern for any animal that we house, control or utilize – and we utilize invertebrates a lot. The Authors start with an emphasis on the values of non-vertebrate animals and discuss the need for a book on the present topic. The following chapters focus on specific taxa, tackling questions that are most appropriate to each one. What is pain in crustaceans, and how might we prevent it? How do we ensure that octopuses are not bored? What do bees need to thrive, pollinate our plants and give us honey? Since invertebrates have distinct personalities and some social animals have group personalities, how do we consider this? And, as in the European Union’s application of welfare consideration to cephalopods, how do the practical regulatory issues play out? We have previously relegated invertebrates to the category ‘things’ and did not worry about their treatment. New research suggest that some invertebrates such as cephalopods and crustaceans can have pain and suffering, might also have consciousness and awareness. Also, good welfare is going to mean different things to spiders, bees, corals, etc. This book is taking animal welfare in a very different direction. Academics and students of animal welfare science, those who keep invertebrates for scientific research or in service to the goals of humans, as well as philosophers will find this work thought-provoking, instructive and informative.




The Experimental Animal in Biomedical Research


Book Description

This volume focuses on considerations that maximize both scientific benefit and animal well-being for major species of animals used in biomedical research. Each species is discussed in terms of uses in research; basic biology; husbandry requirements; proper handling; disease control; anesthesia, analgesia, and stress control; natural behavior, behavioral needs, psychological needs, and social needs; and ideal environment for the animals. This book is a must for anyone working with experimental animals.




Exotic Animal Laboratory Diagnosis


Book Description

Exotic Animal Laboratory Diagnosis is a practical, user-friendly guide to diagnostic testing in a wide range of exotic species. Offers complete information on obtaining samples, performing tests, and interpreting laboratory results in exotic animals Presents information on each species using a similar format for easy access Emphasizes details on clinical biochemistries, urinalysis, and common laboratory diagnostic tests not found in other resources Draws together information on selecting, performing, and using diagnostic tests into a single easy-to-use resource Covers a wide range of species, including small mammals, primates, reptiles, aquatic animals, and wild, laboratory, and pet birds




Invertebrate Medicine


Book Description

Invertebrate Medicine, Second Edition offers a thorough update to the most comprehensive book on invertebrate husbandry and veterinary care. Including pertinent biological data for invertebrate species, the book’s emphasis is on providing state-of-the-art information on medicine and the clinical condition. Invertebrate Medicine, Second Edition is an invaluable guide to the medical care of both captive and wild invertebrate animals. Coverage includes sponges, jellyfish, anemones, corals, mollusks, starfish, sea urchins, crabs, crayfish, lobsters, shrimp, hermit crabs, spiders, scorpions, and many more, with chapters organized by taxonomy. New chapters provide information on reef systems, honeybees, butterfly houses, conservation, welfare, and sources of invertebrates and supplies. Invertebrate Medicine, Second Edition is an essential resource for veterinarians in zoo animal, exotic animal and laboratory animal medicine; public and private aquarists; and aquaculturists.




Advances in Animal Experimentation and Modeling


Book Description

Exploration in Laboratory Animal Sciences Understanding Life Phenomena updates our knowledge about the newer technologies such as molecular biology, genomics including sequencing, proteomics, transcriptomics, cell culture, stem cell culture, transgenesis and their translation to understand systematics and phylogeny of laboratory animals at molecular level. In seven sections Exploration in Laboratory Animal Sciences Understanding Life Phenomena resolves issues of conservation, applications in environment monitoring, production of drugs and others. Comparative research has enabled use of domestic animal models that translate the advances in basic biosciences to the schemes for human welfare including medicine. Molecular geneticists are unravelling the complexities of mammalian genes and the field of biotechnology is maturing at a fast pace. Additionally, research focused on immunology and animal behavior offer new insight into ways of enhancing animal welfare. The rise in consumption of animal proteins in addition to the challenges of sustaining our natural resources has given animal scientists a vast array of opportunities to engage in integrative systems-based research for meeting the challenges that behold us. Exploration in Laboratory Animal Sciences Understanding Life Phenomena also discusses the manipulation of animals as factories for the production of safe foods, drugs, and sensors and others to meet the contemporary challenges faced by mankind in the new world order created by pandemic of Covid 19. It also includes several chapters on the causation and management of certain diseases and impact of microbes on life. - Provides insight to newer and futuristic technologies to understand disease process and drug design by animal models - Addresses a wide variety of species and covers a wide variety of topics (such as animal species, the laboratory setting, regulatory guidelines, and ethical considerations) to fully prepare for work with all types of animals - Gives a perspective on laboratory animal use that allows to explain the benefits of animal use as required by veterinary technology program accreditation procedure - Includes examples of animal bio-technological techniques (including stem cell and tissue engineering) for their applications to humanity - Offers new insight into ways of enhancing animal welfare by the inclusion of research results focused on immunology and laboratory animal behavior




Mass Production of Beneficial Organisms


Book Description

Mass Production of Beneficial Organisms: Invertebrates and Entomopathogens, Second Edition explores the latest advancements and technologies for large-scale rearing and manipulation of natural enemies while presenting ways of improving success rate, predictability of biological control procedures, and demonstrating their safe and effective use. Organized into three sections, Parasitoids and Predators, Pathogens, and Invertebrates for Other Applications, this second edition contains important new information on production technology of predatory mites and hymenopteran parasitoids for biological control, application of insects in the food industry and production methods of insects for feed and food, and production of bumble bees for pollination.Beneficial organisms include not only insect predators and parasitoids, but also mite predators, nematodes, fungi, bacteria and viruses. In the past two decades, tremendous advances have been achieved in developing technology for producing these organisms. Despite that and the globally growing research and interest in biological control and biotechnology applications, commercialization of these technologies is still in progress. This is an essential reference and teaching tool for researchers in developed and developing countries working to produce "natural enemies in biological control and integrated pest management programs. - Highlights the most advanced and current techniques for mass production of beneficial organisms and methods of evaluation and quality assessment - Presents methods for developing artificial diets and reviews the evaluation and assurance of the quality of mass-produced arthropods - Provides an outlook of the growing industry of insects as food and feed and describes methods for mass producing the most important insect species used as animal food and food ingredients