The Cambridge Handbook of Cognitive Aging


Book Description

Decades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach - genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions - this handbook is an essential resource for researchers in cognition, aging, and gerontology.




Models of Cognitive Aging


Book Description

This book offers an updated account of the latest methodological and theoretical issues in cognitive aging. Part of the Debates in Psychology series, it presents the arguments surrounding the currently controversial questions in cognitive aging. What is the appropriate methodology for understanding cognitive change? How many factors are necessary to understand the patterns of age-related change? What might these factors be? The topics and arguments explored in a series of chapters by the leading researchers in the field, and together they cover a broad range of cognitive functions including language use, cognitive slowing, and memory loss.




Alzheimer Disease


Book Description

Alzheimer disease (AD) has become the most common form of dementia in industrialized countries and represents an increasing burden at the economic, social and medical level. In discussing both the biological aspects of AD as well as the cognitive functions involved, Alzheimer Disease - Neuropsychology and Pharmacology presents a comprehensive picture of the pathology and approaches to diagnosis and treatment. Basic research including animal models, molecular and genetic aspects is also taken into consideration. In part I, the biological correlates of AD are discussed. In part II the neuropsychological aspects such as cognitive impairment, loss of functional autonomy and emergence of neuropsychiatric disturbances of AD are outlined. In part III, strategies for effective treatment and prevention of AD are discussed. This book will be a useful source of information for clinicians as well as researchers in the area of neuropharmacology.




The Clinical Neuroscience of Lateralization


Book Description

The Clinical Neuroscience of Lateralization gives the first comprehensive transdiagnostic overview of the evidence for changes in hemispheric asymmetries in different psychiatric and neurodevelopmental disorders. Taking a multidisciplinary perspective informed by both basic science and clinical studies, the authors integrate recent breakthroughs on hemispheric asymmetries in psychology, neuroscience, genetics and comparative research. They give a general introduction to hemispheric asymmetries and the techniques used to assess them, and review the evidence for changes in hemispheric asymmetries in different psychiatric and neurodevelopmental disorders. The book also discusses neurological disorders like Parkinson's disease and multiple sclerosis and highlights the importance of open science in clinical laterality research. Offering a fresh perspective on a longstanding issue in clinical neuroscience, this book will be of great interest for academics, researchers, and students in the fields of clinical and developmental neuroscience, biopsychology and neuropsychology.




Cerebrospinal Fluid Biomarkers


Book Description

This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research. Chapters in this book discuss topics such as techniques for cerebrospinal fluid (CSF) collection, pre-analytical processing, and basic CSF analysis; an examination of biomarkers including ELISA and automated immunochemical assays for amyloid and tau markers for Alzheimer’s disease; the analysis of neurofilaments by digital ELISA; and an example of successful novel immunoassay development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Cerebrospinal Fluid Biomarkers is a valuable resource for clinicians and researchers to use in CSF labs and CSF courses.




The Neurology of Religion


Book Description

Examines what can be learnt about the brain mechanisms underlying religious practice from studying people with neurological disorders.




Clinical Staging in Psychiatry


Book Description

Clinical staging is a solution to transform psychiatric diagnosis and improve mental health outcomes.




Neuro-Geriatrics


Book Description

This manual takes a multidisciplinary approach to neurological disorders in the elderly. Comprehensive and practical, it includes the most recent diagnostic criteria and immediately accessible visual care paths including the latest pharmacologic and non-pharmacologic interventions. Covering a range of modalities, from the importance and impact of each disease to diagnostic criteria, genetics, laboratory and imaging findings, treatment and care paths, this book focuses on neurological conditions that occur commonly in older persons or which have a striking effect on their lives. The common types of dementias, Parkinson’s disease and related disorders, rapidly progressive diseases, seizure disorders and multiple sclerosis are covered. Issues commonly affecting this population, such as neurobehavioral symptoms and caregiver issues, are discussed. Neuro-Geriatrics: A Clinical Manual is aimed at any physician who treats the elderly with neurological disorders: neurologists, geriatricians and geriatric psychiatrists, both specialists and general practitioners.




Taurine 10


Book Description

Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.




Sex Hormones in Neurodegenerative Processes and Diseases


Book Description

The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.