Laser Systems for Photobiology and Photomedicine


Book Description

This volume contains the Proceedings of a two-week NATO Advanced Study Institute on "Laser Systems for Photobiology and Photomedicine", conducted from May 11 to 20, 1990 in Erice, Italy. This is the 15th annual course of the International School of Quantum Electronics (ISQE), organized under the auspices of the "Ettore Majorana" Center for Scientific Culture. The application of lasers to medicine and surgery has made amazing progress since the last ISQE Course on this subject in 1983. The present Proceedings give a tutorial introduction to today's most important areas, as well as a review of current results by leading researchers. Among the possible approaches to a NATO Advanced Study Institute on Laser Systems for Photobiology and Photomedicine, we chose to emphasize the scientific and technological aspects of advanced laser systems when applied to laboratory and clinical tests. Since it is the policy of the School to stress the advanced scientific and techn·ological achievements in the field of Quantum Electronics, the Course broadly covers performance already achieved and potential applications.




Laser Photobiology and Photomedicine


Book Description

This volume contains the Proceedings of a two-week course on "Laser Applications to Biology and Medicine" held from September 4 to 16, 1983 in Erice, Italy. This is the 10th annual course of the International School of Quantum Electronics organized under the auspices of the "E. Majorana" Center for Scientific Culture. ,Among the possible approaches to a course on Laser Applications to Biology and Medicine, the one which emphasizes the scientific and technological aspects of the advanced laser techniques when applied to laboratory and clinical tests has been chosen. In fact, it reflects the new policy of the School to stress the advanced scien tific and technological achievements in the field of Quantum Elec tronics. Accordingly, the Course has given the broadest information on the ultimate performances already achieved and the perspectives of their applications. Because of the great variety of applications of laser in biology, medicine, chemistry, engineering and related branches of science, this school addressed a subject of interdisciplinary interest. The formal sessions have been balanced between tutorial presentations and lectures focusing on unsolved problems and future directions. In addition, wide time has been provided for the par ticipants to meet together informally for additional discussions on the forefront of current work. Therefore the character of the Course was a blend of current research and tutorial reviews.




Current Catalog


Book Description

First multi-year cumulation covers six years: 1965-70.




Lasers in Photomedicine and Photobiology


Book Description

This Conference on biomedical applications of. lasers ~Ias organized by the Quantum Electronics Divisional Board of the European Physical Society (E.P.S.) and held at the Villa of Poggio Imperiale in Florence, September 3-6, 1979. As kno~m, laser surgery (especially microsurgery and endoscopic photo coagulation) has recently made important progress, and the field is expand i ng rapidly. Very significant applications of lasers have also been achieved in Bi ology during recent years (cell microsurgery, cell counting and sorting, cytofluorimeter devices, etc.) and the potential of laser techniques in this field is nO~1 sufficiently well establ ished. A new class of applications of laserradiJtion in Medicine has recently been made possible by important results obtained with low intensity (non coagulative) visible lasers, such as photodynamic therapy of tumors. At the same time important branches of Medicine, where light effects are studied and optical techniques are presently used for a certain number of clinical applications, such as dermatology and pediatry, appear to be still in their infancy as far as the proper use of optical radiation and techniques, and the understanding of fundamental photoinduced biological processes are con cerned. Moreover, laser photobiology appears a very promising field for the investigation of fundamental processes at the biomolecular level.




Photomedicine and Stem Cells


Book Description

Janus, the ancient Roman god depicted with two faces is an appropriate metaphor for light therapy. In the right photodynamic therapy conditions, light is able to kill nearly anything that is living such as cancers, microorganisms, parasites, and more. On the opposite face, light of the correct wavelength and proper dose (photobiomodulation) can heal, regenerate, protect, revitalize and restore any kind of dead, damaged, stressed, dying, degenerating cells, tissue, or organ system. This book discusses both sides of Janus' face in regards to light therapy.




Laser Science and Technology


Book Description

The conference "Laser Science and Technology" was held May 11-19, 1987 in Erice, Sicily. This was the 12th conference organized by the Internatio nal School of Quantum Electronics, under the auspices of the "Ettore Majorana" Center for Scientific Culture. This volume contains both the in vited and contributed papers presented at the conference, covering current research work in two areas: new laser sources, and laser applications. The operation of the first laser by Dr. Theodore Maiman in 1960 initia ted a decade of scientific exploration of new laser sources. This was fol lowed by the decade of the 1970s, which was characterized by "technology push" in which the discoveries of the 1960s were seeking practical applica tion. In the 1980s we are instead seeking "applications pull," in which the success and rapid maturing of laser applications provides both inspiration and financial resources to stimulate additional work both on laser sources and applications. The papers presented in these Proceedings attest to the great vitali ty of research in both these areas: New Laser Sources. The papers describe current developments in ultra violet excimer lasers, X-ray lasers, and free electron lasers. These new lasers share several characteristics: each is a potentially important coher ent source; each is at a relatively short wavelength (below 1 micrometer); and each is receiving significant development attention today.




Applications of Minimally Invasive Nanomedicine-Based Therapies in 3D in vitro Cancer Platforms


Book Description

Minimally invasive techniques such as Photodynamic Therapy (PDT) and Photochemical Internalisation (PCI) have for years been under investigation for the treatment of solid cancers. A significant number of the recent research studies have applied PDT and PCI to biological three-dimensional (3D) cancer platforms with many of the studies also involving the use of nanoparticles in order to enhance the efficacy of these light-based therapies. Interest in the employment of 3D cancer platforms has increased considerably due to the ability of the platforms to mimic in vivo models better than the conventional two-dimensional (2D) cultures. Some of the advantages of the 3D cancer systems over their 2D counterparts include improved interaction between cancer cells and the surrounding extracellular matrix (ECM) as well as restricted drug penetration which would allow optimization of treatments prior to undertaking of in vivo studies. The different chapters of this book will discuss photosensitizers and nanoparticles used in PDT and PCI in addition to the applications of these treatments in various 3D cancer models.




Introduction to Physics in Modern Medicine


Book Description

From x-rays to lasers to magnetic resonance imaging, developments in basic physics research have been transformed into medical technologies for imaging, surgery and therapy at an ever-accelerating pace. Physics has joined with genetics and molecular biology to define much of what is modern in modern medicine and allied health. Covering a wide range of applications, Introduction to Physics in Modern Medicine, Third Edition builds further on the bestselling second edition. Based on the courses taught by the authors, the book provides medical personnel and students with an exploration of the physics-related applications found in state-of-the-art medical centers. Requiring no previous acquaintance with physics, biology, or chemistry and keeping mathematics to a minimum, the application-dedicated chapters adhere to simple and self-contained qualitative explanations that make use of examples, illustrations, clinical applications, sample calculations, and exercises. With an enhanced emphasis on digital imaging and computers in medicine, the text gives readers a fundamental understanding of the practical application of each concept and the basic science behind it. This book provides medical students with an excellent introduction to how physics is applied in medicine, while also providing students in physics with an introduction to medical physics. Each chapter includes worked examples and a complete list of problems and questions. That so much of the technology discussed in this book was the stuff of dreams just a few years ago, makes this book as fascinating as it is practical, both for those in medicine as well as those in physics who might one day discover that the project they are working on is the basis for the next great medical application. Features: · Introduces state-of-the-art and emerging medical technologies such as optical coherence tomography, x-ray phase contrast imaging, and ultrasound-mediated drug delivery · Covers hybrid scanners for cancer imaging and the interplay of molecular medicine with MRI, CT and PET in addition to intensity-modulated radiation therapy and new forms of cancer treatments such as proton and heavy-ion therapies · Offers an enhanced emphasis on digital imaging and dosimetry including recent innovations in the pixel-array x-ray detectors, ultrasound matrix transducers and direct-ion storage dosimeters




Biomedical Optical Instrumentation and Laser-Assisted Biotechnology


Book Description

The NATO Advanced Study Institute "Biomedical Optical Instrumentation and Laser Assisted Biotechnology" was held November 10-22, 1995 in Erice, Sicily. This was the 19 th conference organized by the International School of Quantum Electronics, under the auspices of the "Ettore Majorana" Center for Scientific Culture. The contributions presented at the Institute are written as extended, review-like papers to provide a broad and representative coverage of the fields of laser techniques, optoelectronics systems for medical diagnosis, and light and laser applications to Biology and Medicine. The aim of the Institute was to bring together some of the world's acknowledged scientists and clinicians that belong to different disciplines and consequently do not usually meet, but who have as a common link the use of optoelectronics instrumentation, techniques and procedures. Most of the lecturers attended all the lectures and devoted their spare hours to stimulating discussions. We would like to thank them all for their admirable contributions. The Institute also took advantage of a very active audience; most of the participants were active researchers in the field and contributed with discussions and seminars. Some of these seminars are also included in these Proceedings. The Institute was an important opportunity to discuss latest developments and emerging perspectives on the use of laser sources and optoelectronic techniques for diagnostic and therapeutic purposes.