The Future of Aging


Book Description

Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.




Life Extension


Book Description

Discusses various aspects of aging and includes suggestions on how to slow the aging process and improve your health.




Life Extension Design


Book Description

In this book, you'll find a workshop of sorts. A workshop to redesign your life for optimal health, performance, and longevity in order to become part of the first generation to choose whether to age and die ... or not. If you're reading this, you live in the most exciting time of human history. Within the next decades, exponential technologies will not only dramatically change the world we live in, but also the biology of our bodies. By using cellular and molecular repair therapies and reprogramming our DNA, we will be able to reverse the aging process and make aging and death optional. Although we're talking about the world of tomorrow, there is so much you can do today to become part of that future. This practical handbook empowers you to experiment with ways to playfully improve and optimize your health and extend your healthy lifespan. Find out how to increase your energy level and overall well-being while simultaneously adding healthy years to your life. And you don't have to torture yourself, thanks to design-thinking methods; this redesign of your life can be done in a fun way. Just think of it as a workshop. In this book, you'll find:- Introductions to life extension and design thinking- Inputs and best practices for nutrition, exercise, mental well-being, detoxification, quantified self, prevention, advanced action, and information detox- Simple intuitive frameworks to capture your situations, run experiments, and orchestrate your life areas- A strategic approach to master your health design in the long runExtending your healthy lifespan to live as long as you want. Is it worth a shot?




The Mindspan Diet


Book Description

A comprehensive, easy-to-use guide to the foods that curb memory loss and improve cognitive longevity, this book will forever change how you think about diet and aging. Even though people around the world are living longer than ever, but record numbers of us are experiencing cognitive decline and other brain disorders later in life. But there is good news: We now have the knowledge to extend both lifespan and mindspan, helping to ensure that our minds and bodies stay in peak form at any age. Studying the diets of the populations that live longest with low levels of dementia, as well as the ways that certain food additives and ingredients interact with our genes, Dr. Preston Estep shatters myths about which foods are (and are not) beneficial to our brains, with simple changes you can make today to slow cognitive decline. Startling in its revelations about healthy eating for those over the age of fortyThe Mindspan Diet challenges us to rethink our approach to many common staples, including: • Iron: While iron-fortified foods sound healthy, high iron intake can be toxic, especially for people over forty, and increases the risk of type 2 diabetes, Alzheimer’s, and Parkinson’s disease. • Whole grains: Processed grains such as white rice, pasta, and flour are actually staples in the diets of cultures with the best cognitive health. • Protein: Though it’s considered by some to be a miracle macronutrient, high levels of protein are actually hard on the kidneys, and may promote cancer and accelerate the progression of dementia. Complete with food recommendations, shopping lists, advice on reading nutrition labels, and more than seventy delicious recipes, The Mindspan Diet shows that you can enjoy the richest flavors life has to offer and remain lean, healthy, and cognitively intact for a very long life. Praise for The Mindspan Diet “Eye-opening . . . fascinating, important . . . Estep includes plenty of practical info on improving one’s mindspan and puts some refined grains back on the table.”—Publishers Weekly (starred review) “Presenting a sensible regimen that people can follow easily, this recommended diet book [has] useful information about aging.”—Library Journal




The Case against Death


Book Description

A philosopher refutes our culturally embedded acceptance of death, arguing instead for the desirability of anti-aging science and radical life extension. Ingemar Patrick Linden’s central claim is that death is evil. In this first comprehensive refutation of the most common arguments in favor of human mortality, he writes passionately in favor of antiaging science and radical life extension. We may be on the cusp of a new human condition where scientists seek to break through the arbitrarily set age limit of human existence to address aging as an illness that can be cured. The book, however, is not about the science and technology of life extension but whether we should want more life. For Linden, the answer is a loud and clear “yes.” The acceptance of death is deeply embedded in our culture. Linden examines the views of major philosophical voices of the past, whom he calls “death’s ardent advocates.” These include the Buddha, Socrates, Plato, Lucretius, and Montaigne. All have taught what he calls “the Wise View,” namely, that we should not fear death. After setting out his case against death, Linden systematically examines each of the accepted arguments for death—that aging and death are natural, that death is harmless, that life is overrated, that living longer would be boring, and that death saves us from overpopulation. He concludes with a “dialogue concerning the badness of human mortality.” Though Linden acknowledges that The Case Against Death is a negative polemic, he also defends it as optimistic, in that the badness of death is a function of the goodness of life.




Ageing and Life Extension of Offshore Structures


Book Description

A comprehensive overview of managing and assessing safety and functionality of ageing offshore structures and pipelines A significant proportion, estimated at over 50%, of the worldwide infrastructure of offshore structures and pipelines is in a life extension phase and is vulnerable to ageing processes. This book captures the central elements of the management of ageing offshore structures and pipelines in the life extension phase. The book gives an overview of: the relevant ageing processes and hazards; how ageing processes are managed through the life cycle, including an overview of structural integrity management; how an engineer should go about assessing a structure that is to be operated beyond its original design life, and how ageing can be mitigated for safe and effective continued operation. Key Features: Provides an understanding of ageing processes and how these can be mitigated. Applies engineering methods to ensure that existing structures can be operated longer rather than decommissioned unduly prematurely. Helps engineers performing these tasks in both evaluating the existing structures and maintaining ageing structures in a safe manner. The book gives an updated summary of current practice and research on the topic of the management of ageing structures and pipelines in the life extension phase but also meets the needs of structural engineering students and practicing offshore and structural engineers in oil & gas and engineering companies. In addition, it should be of value to regulators of the offshore industry.




Handbook of Materials Selection


Book Description

Erstmals in einem Band werden Werkstoffe hier (in zwei getrennten Systemen) sowohl nach ihrer technischen Anwendung als auch nach ihren Eigenschaften geordnet. - Benutzer können deshalb zunächst nach der Gruppe von Materialen suchen, die für eine spezielle Anwendung geeignet sind, und anschließend Details über jedes einzelne Material finden - Suchkriterien sind Eigenschaften wie Wärmeleitfähigkeit, optisches Reflexionsvermögen, Elastizität usw. und Anwendungsgebiete wie Bauwesen, Biomedizin, Fahrzeugbau, Luftfahrttechnik, Elektrotechnik usw. - berücksichtigt werden sowohl herkömmliche Werkstoffe (Eisen- und Nichteisenmetalle, Kunststoffe, Klebstoffe) als auch Kompositwerkstoffe und synthetische Materialen wie Laminate, Fasern und Keramiken




Health Building and Life Extension


Book Description




Over 200 U.S. Department of Energy Manuals Combined: CLASSICAL PHYSICS; ELECTRICAL SCIENCE; THERMODYNAMICS, HEAT TRANSFER AND FLUID FUNDAMENTALS; INSTRUMENTATION AND CONTROL; MATHEMATICS; CHEMISTRY; ENGINEERING SYMBIOLOGY; MATERIAL SCIENCE; MECHANICAL SCIENCE; AND NUCLEAR PHYSICS AND REACTOR THEORY


Book Description

Over 19,000 total pages ... Public Domain U.S. Government published manual: Numerous illustrations and matrices. Published in the 1990s and after 2000. TITLES and CONTENTS: ELECTRICAL SCIENCES - Contains the following manuals: Electrical Science, Vol 1 - Electrical Science, Vol 2 - Electrical Science, Vol 3 - Electrical Science, Vol 4 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 1 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 2 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 3 - Instrumentation And Control, Vol 1 - Instrumentation And Control, Vol 2 Mathematics, Vol 1 - Mathematics, Vol 2 - Chemistry, Vol 1 - Chemistry, Vol 2 - Engineering Symbology, Prints, And Drawings, Vol 1 - Engineering Symbology, Prints, And Drawings, Vol 2 - Material Science, Vol 1 - Material Science, Vol 2 - Mechanical Science, Vol 1 - Mechanical Science, Vol 2 - Nuclear Physics And Reactor Theory, Vol 1 - Nuclear Physics And Reactor Theory, Vol 2. CLASSICAL PHYSICS - The Classical Physics Fundamentals includes information on the units used to measure physical properties; vectors, and how they are used to show the net effect of various forces; Newton's Laws of motion, and how to use these laws in force and motion applications; and the concepts of energy, work, and power, and how to measure and calculate the energy involved in various applications. * Scalar And Vector Quantities * Vector Identification * Vectors: Resultants And Components * Graphic Method Of Vector Addition * Component Addition Method * Analytical Method Of Vector Addition * Newton's Laws Of Motion * Momentum Principles * Force And Weight * Free-Body Diagrams * Force Equilibrium * Types Of Force * Energy And Work * Law Of Conservation Of Energy * Power – ELECTRICAL SCIENCE: The Electrical Science Fundamentals Handbook includes information on alternating current (AC) and direct current (DC) theory, circuits, motors, and generators; AC power and reactive components; batteries; AC and DC voltage regulators; transformers; and electrical test instruments and measuring devices. * Atom And Its Forces * Electrical Terminology * Units Of Electrical Measurement * Methods Of Producing Voltage (Electricity) * Magnetism * Magnetic Circuits * Electrical Symbols * DC Sources * DC Circuit Terminology * Basic DC Circuit Calculations * Voltage Polarity And Current Direction * Kirchhoff's Laws * DC Circuit Analysis * DC Circuit Faults * Inductance * Capacitance * Battery Terminology * Battery Theory * Battery Operations * Types Of Batteries * Battery Hazards * DC Equipment Terminology * DC Equipment Construction * DC Generator Theory * DC Generator Construction * DC Motor Theory * Types Of DC Motors * DC Motor Operation * AC Generation * AC Generation Analysis * Inductance * Capacitance * Impedance * Resonance * Power Triangle * Three-Phase Circuits * AC Generator Components * AC Generator Theory * AC Generator Operation * Voltage Regulators * AC Motor Theory * AC Motor Types * Transformer Theory * Transformer Types * Meter Movements * Voltmeters * Ammeters * Ohm Meters * Wattmeters * Other Electrical Measuring Devices * Test Equipment * System Components And Protection Devices * Circuit Breakers * Motor Controllers * Wiring Schemes And Grounding THERMODYNAMICS, HEAT TRANSFER AND FLUID FUNDAMENTALS. The Thermodynamics, Heat Transfer, and Fluid Flow Fundamentals Handbook includes information on thermodynamics and the properties of fluids; the three modes of heat transfer - conduction, convection, and radiation; and fluid flow, and the energy relationships in fluid systems. * Thermodynamic Properties * Temperature And Pressure Measurements * Energy, Work, And Heat * Thermodynamic Systems And Processes * Change Of Phase * Property Diagrams And Steam Tables * First Law Of Thermodynamics * Second Law Of Thermodynamics * Compression Processes * Heat Transfer Terminology * Conduction Heat Transfer * Convection Heat Transfer * Radiant Heat Transfer * Heat Exchangers * Boiling Heat Transfer * Heat Generation * Decay Heat * Continuity Equation * Laminar And Turbulent Flow * Bernoulli's Equation * Head Loss * Natural Circulation * Two-Phase Fluid Flow * Centrifugal Pumps INSTRUMENTATION AND CONTROL. The Instrumentation and Control Fundamentals Handbook includes information on temperature, pressure, flow, and level detection systems; position indication systems; process control systems; and radiation detection principles. * Resistance Temperature Detectors (Rtds) * Thermocouples * Functional Uses Of Temperature Detectors * Temperature Detection Circuitry * Pressure Detectors * Pressure Detector Functional Uses * Pressure Detection Circuitry * Level Detectors * Density Compensation * Level Detection Circuitry * Head Flow Meters * Other Flow Meters * Steam Flow Detection * Flow Circuitry * Synchro Equipment * Switches * Variable Output Devices * Position Indication Circuitry * Radiation Detection Terminology * Radiation Types * Gas-Filled Detector * Detector Voltage * Proportional Counter * Proportional Counter Circuitry * Ionization Chamber * Compensated Ion Chamber * Electroscope Ionization Chamber * Geiger-Müller Detector * Scintillation Counter * Gamma Spectroscopy * Miscellaneous Detectors * Circuitry And Circuit Elements * Source Range Nuclear Instrumentation * Intermediate Range Nuclear Instrumentation * Power Range Nuclear Instrumentation * Principles Of Control Systems * Control Loop Diagrams * Two Position Control Systems * Proportional Control Systems * Reset (Integral) Control Systems * Proportional Plus Reset Control Systems * Proportional Plus Rate Control Systems * Proportional-Integral-Derivative Control Systems * Controllers * Valve Actuators MATHEMATICS The Mathematics Fundamentals Handbook includes a review of introductory mathematics and the concepts and functional use of algebra, geometry, trigonometry, and calculus. Word problems, equations, calculations, and practical exercises that require the use of each of the mathematical concepts are also presented. * Calculator Operations * Four Basic Arithmetic Operations * Averages * Fractions * Decimals * Signed Numbers * Significant Digits * Percentages * Exponents * Scientific Notation * Radicals * Algebraic Laws * Linear Equations * Quadratic Equations * Simultaneous Equations * Word Problems * Graphing * Slopes * Interpolation And Extrapolation * Basic Concepts Of Geometry * Shapes And Figures Of Plane Geometry * Solid Geometric Figures * Pythagorean Theorem * Trigonometric Functions * Radians * Statistics * Imaginary And Complex Numbers * Matrices And Determinants * Calculus CHEMISTRY The Chemistry Handbook includes information on the atomic structure of matter; chemical bonding; chemical equations; chemical interactions involved with corrosion processes; water chemistry control, including the principles of water treatment; the hazards of chemicals and gases, and basic gaseous diffusion processes. * Characteristics Of Atoms * The Periodic Table * Chemical Bonding * Chemical Equations * Acids, Bases, Salts, And Ph * Converters * Corrosion Theory * General Corrosion * Crud And Galvanic Corrosion * Specialized Corrosion * Effects Of Radiation On Water Chemistry (Synthesis) * Chemistry Parameters * Purpose Of Water Treatment * Water Treatment Processes * Dissolved Gases, Suspended Solids, And Ph Control * Water Purity * Corrosives (Acids And Alkalies) * Toxic Compound * Compressed Gases * Flammable And Combustible Liquids ENGINEERING SYMBIOLOGY. The Engineering Symbology, Prints, and Drawings Handbook includes information on engineering fluid drawings and prints; piping and instrument drawings; major symbols and conventions; electronic diagrams and schematics; logic circuits and diagrams; and fabrication, construction, and architectural drawings. * Introduction To Print Reading * Introduction To The Types Of Drawings, Views, And Perspectives * Engineering Fluids Diagrams And Prints * Reading Engineering P&Ids * P&Id Print Reading Example * Fluid Power P&Ids * Electrical Diagrams And Schematics * Electrical Wiring And Schematic Diagram Reading Examples * Electronic Diagrams And Schematics * Examples * Engineering Logic Diagrams * Truth Tables And Exercises * Engineering Fabrication, Construction, And Architectural Drawings * Engineering Fabrication, Construction, And Architectural Drawing, Examples MATERIAL SCIENCE. The Material Science Handbook includes information on the structure and properties of metals, stress mechanisms in metals, failure modes, and the characteristics of metals that are commonly used in DOE nuclear facilities. * Bonding * Common Lattice Types * Grain Structure And Boundary * Polymorphism * Alloys * Imperfections In Metals * Stress * Strain * Young's Modulus * Stress-Strain Relationship * Physical Properties * Working Of Metals * Corrosion * Hydrogen Embrittlement * Tritium/Material Compatibility * Thermal Stress * Pressurized Thermal Shock * Brittle Fracture Mechanism * Minimum Pressurization-Temperature Curves * Heatup And Cooldown Rate Limits * Properties Considered * When Selecting Materials * Fuel Materials * Cladding And Reflectors * Control Materials * Shielding Materials * Nuclear Reactor Core Problems * Plant Material Problems * Atomic Displacement Due To Irradiation * Thermal And Displacement Spikes * Due To Irradiation * Effect Due To Neutron Capture * Radiation Effects In Organic Compounds * Reactor Use Of Aluminum MECHANICAL SCIENCE. The Mechanical Science Handbook includes information on diesel engines, heat exchangers, pumps, valves, and miscellaneous mechanical components. * Diesel Engines * Fundamentals Of The Diesel Cycle * Diesel Engine Speed, Fuel Controls, And Protection * Types Of Heat Exchangers * Heat Exchanger Applications * Centrifugal Pumps * Centrifugal Pump Operation * Positive Displacement Pumps * Valve Functions And Basic Parts * Types Of Valves * Valve Actuators * Air Compressors * Hydraulics * Boilers * Cooling Towers * Demineralizers * Pressurizers * Steam Traps * Filters And Strainers NUCLEAR PHYSICS AND REACTOR THEORY. The Nuclear Physics and Reactor Theory Handbook includes information on atomic and nuclear physics; neutron characteristics; reactor theory and nuclear parameters; and the theory of reactor operation. * Atomic Nature Of Matter * Chart Of The Nuclides * Mass Defect And Binding Energy * Modes Of Radioactive Decay * Radioactivity * Neutron Interactions * Nuclear Fission * Energy Release From Fission * Interaction Of Radiation With Matter * Neutron Sources * Nuclear Cross Sections And Neutron Flux * Reaction Rates * Neutron Moderation * Prompt And Delayed Neutrons * Neutron Flux Spectrum * Neutron Life Cycle * Reactivity * Reactivity Coefficients * Neutron Poisons * Xenon * Samarium And Other Fission Product Poisons * Control Rods * Subcritical Multiplication * Reactor Kinetics * Reactor




Nuclear Weapons


Book Description

U.S. nuclear weapons are aging, with key components reaching the end of their service life. In September 2008, the Department of Defense (DoD) and the National Nuclear Security Admin. (NNSA) began a study of military requirements and design options for extending the B61 bomb¿s service life. The B61 supports the U.S. strategic deterrent and NATO. This report assessed the extent to which DoD and NNSA have: (1) considered the time available to begin producing refurbished bombs when determining the scope of the study; and (2) taken actions to avoid operational gaps in U.S. nuclear weapons commitments to NATO during the life extension program. Includes recommend. Illus. This is a print on demand report.