Application of LC-MS/MS in the Mycotoxins Studies


Book Description

Mycotoxins are secondary metabolites produced by the fungi of different species (mainly Aspergillus, Fusarium, and Penicillium), with toxic effects for humans and animals. These mycotoxins can contaminate food and feed. The European Union (EU) has established the maximum permitted or recommended levels for well-known mycotoxins in different foodstuffs. However, there are other mycotoxins that are not included in the regulations: the “emerging mycotoxins” (whose toxicity is still not clear), and the “modified or masked mycotoxins” (produced as a consequence of a detoxification strategy of the host plant of the fungus or during food processing). These mycotoxins could pose a risk and should also be taken into account. In order to assure consumers’ health, analytical methods for the accurate determination of mycotoxins in different food matrices and feeds are required. In this sense, liquid chromatography tandem mass spectrometry (LC–MS/MS) is a powerful tool for their unique identification and quantification. Moreover, the use of high-resolution mass spectrometry (HRMS) allows one to identify novel mycotoxins and targeted/untargeted approaches for study. This Special Issue compiles recent applications of LC–MS/MS in mycotoxin studies, as well as the development and validation of new analytical methods for their identification and quantification in different food matrices and feed, occurrence studies, and the biomonitoring of mycotoxins and their metabolites in biological fluids.




Fusarium


Book Description

Contains a tribute to Paul E. Nelson, plus biographical information.




LC-MS/MS Method for Mycotoxin Analysis


Book Description

This book is a printed edition of the Special Issue "LC-MS/MS Method for Mycotoxin Analysis" that was published in Toxins




Nanomycotoxicology


Book Description

Nanomycotoxicology: Treating Mycotoxins in Nanoway discusses the role of nanotechnology in the detection, toxicity and management of different types of mycotoxins. Sections cover the topic of nanomycotoxicology, the application of nanotechnology for quicker, more cost-effective and precise diagnostic procedures of mycotoxins and toxicogenic fungi, and the application of nanotechnology for the management of mycotoxigenic fungi. New topics, such as the application of nanotechnology in disease management, disease forecasting, and disease resistance, mycotoxin detection, and nanodiagnostic and molecular techniques are also presented. With chapter contributions from an international group of experts, this book presents an interdisciplinary reference for scientists and researchers working in mycotoxicology, nanotechnology, mycology, plant science, and food safety. In addition, it will be a useful tool for industrial scientists investigating technologies to update their nanotoxicology and nanosafety knowledge. - Discusses the role of nanotechnology in mycotoxicology - Explores the application of nanomaterials for detection of mycotoxins - Covers the role of nanotechnology in the management of mycotoxins and mycotoxigenic fungi




Masked Mycotoxins in Food


Book Description

The first book to cover this fast developing field, Masked Mycotoxins in Food will provide a full overview of the issues relating to the toxicology of masked mycotoxins present in food products. Mycotoxins are naturally occurring chemicals produced by moulds that can grow on crops and foodstuffs. Masked mycotoxins are modified mycotoxins, due to this modification many cannot be detected using standard analytical techniques, for example HPLC and ELISA, and further research is needed to understand the health risks and threats from these modified compounds.Masked mycotoxin research is an area of toxicological research that has gained significant interest and momentum in recent years. The aim of this book is to provide a full picture of the topic, from the masked mycotoxin formation in plants to their catabolic fate in humans. The book also provides new insights and will highlight possible gaps in the knowledge base of this relatively new area. Edited and written by World renowned experts working within the field, this book is of interest to toxicologists and biochemists, but also food scientists and agricultural researchers working in industry and academia.




Mycotoxins in Food


Book Description

Full text, included in Knovel Library within the subject area of Chemistry and Chemical Engineering.




Food Analysis by HPLC


Book Description

For food scientists, high-performance liquid chromatography (HPLC) is a powerful tool for product composition testing and assuring product quality. Since the last edition of this volume was published, great strides have been made in HPLC analysis techniques-with particular attention given to miniaturization, automatization, and green chemistry. Tho




Diagnosis of Mycotoxicoses


Book Description

Current problems associated with the mycotoxicoses include the recognition of an animal disease as being a mycotoxicosis and confirmation of diagnosis of the mycotoxicosis by satisfactory laboratory methods. By gathering a vast amount of scientific literature, diagnosticians can provide themselves with suitable informa tion for making such a diagnosis. However, the increased number of reported intoxications caused by fungi, the wide range in diversity of disease conditions and the chemical compounds causing the mycotoxicoses, and the ever-changing and rapid developments in the technology of mycotoxin analysis has made the gathering and assimilation of sufficient information by the diagnostician an insurmountable task. This is the reason for development of the symposium and the publication of this book; the first time that the subject of diagnosis of mycotoxicoses has been assembled in a single publication and as a compilation of topic papers by experts in this subject area. The UJNR panel on toxic microorganisms is interested in all aspects of intox ications by microorganisms as evidenced by its annual joint meetings in either the United States or Japan and its involvement in sponsoring numerous symposia and several publications in this broad scientific area. The overall mission of the National Animal Disease Center includes research efforts in the improvement or establishment of diagnostic methods for animal diseases. The UJNR panel and the NADC provided the funds and encouragement for the development of a symposium on the diagnosis of mycotoxicoses in the United States and . Tapan.




Analysis of Food Toxins and Toxicants, 2 Volume Set


Book Description

Analysis of Food Toxins and Toxicants consists of five sections, providing up-to-date descriptions of the analytical approaches used to detect a range of food toxins. Part I reviews the recent developments in analytical technology including sample pre-treatment and food additives. Part II covers the novel analysis of microbial and plant toxins including plant pyrrolizidine alkaloids. Part III focuses on marine toxins in fish and shellfish. Part IV discusses biogenic amines and common food toxicants, such as pesticides and heavy metals. Part V summarizes quality assurance and the recent developments in regulatory limits for toxins, toxicants and allergens, including discussions on laboratory accreditation and reference materials.




Mycotoxins in Fruits and Vegetables


Book Description

Mycotoxins are toxins produced by aerobic, microscopic fungus under special conditions of moisture and temperature. They colonize in a variety of foods from harvest to the grocer. Mycotoxins have gained world wide interest in recent years with the revelation of the effect of these toxins on health. A current example is the presence of ochratoxin A, a human carcinogen and nephrotoxin, in wines. The increased concern about fruit safety has led to increased studies throughout the world and enhanced awareness for stringent regulations governing mycotoxin limits in food.Presented in three defined sections, this is the first book to provide comprehensive analysis of the main mycotoxins contaminating fruits and vegetables and their derived products. The first section provides a safety evaluation of mycotoxins in fruits and vegetables, details regarding factors affecting mycotoxin production and diffusion in the fruit tissue, and recent methods for detection of mycotoxigenic fungi and mycotoxins produced by the fungi. The second part takes a critical look at the main individual mycotoxins and the third section focuses on approaches for prevention and control. - The first book dedicated to mycotoxins in fruits and vegetables - Presents mycological, mycotoxicological and phytopathological aspects of fruits and vegetables - Includes an analysis of detection, prevention and control methods for mycotoxigenic fungi and the mycotoxins they produce - Provides a complete risk assessment and safety evaluation of mycotoxins in perishable produce