Mass Spectrometry for the Novice


Book Description

With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers. The extraordinary versatility can make mass spectrometers daunting to novices. Consequently, new users would benefit greatly from an understanding of the basic concepts as well as the processes that occur in these instruments. Mass Spectrometry for the Novice provides exactly that, with detailed, straightforward descriptions and clear illustrations of principles of operations and techniques. The book begins with an overview that includes essential definitions and then provides information on the components of and the strategies used in the most common instruments. The authors discuss the methodologies available, classes of compounds analyzed, and the types of data that can be generated. A group of representative applications from published articles is summarized, demonstrating the diversity of mass spectrometry. The authors also condense the essentials of the topic into one invaluable chapter that provides a set of concise take-home messages on all aspects of mass spectrometry. The final section provides a collection of resources including books, reviews, and useful websites. Using simple language, new color figures, clever cartoons, and assuming no prior knowledge, this book provides a readily understandable entrée to mass spectrometry. A CD-ROM with selected figures and cartoons is included.




Mass Spectrometry for the Novice


Book Description

With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers. The extraordinary versatility can make mass spectrometers daunting to novices. Consequently, new users would benefit greatly from an understanding of the basic concepts as well as the processes that occur in these instruments. Mass Spectrometry for the Novice provides exactly that, with detailed, straightforward descriptions and clear illustrations of principles of operations and techniques. The book begins with an overview that includes essential definitions and then provides information on the components of and the strategies used in the most common instruments. The authors discuss the methodologies available, classes of compounds analyzed, and the types of data that can be generated. A group of representative applications from published articles is summarized, demonstrating the diversity of mass spectrometry. The authors also condense the essentials of the topic into one invaluable chapter that provides a set of concise take-home messages on all aspects of mass spectrometry. The final section provides a collection of resources including books, reviews, and useful websites. Using simple language, new color figures, clever cartoons, and assuming no prior knowledge, this book provides a readily understandable entrée to mass spectrometry. Downloadable resources with selected figures and cartoons is included.




Mass Spectrometry for the Novice


Book Description

With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers




A Beginner's Guide to Mass Spectral Interpretation


Book Description

Die Massenspektrometrie ist eine der wenigen Techniken, mit denen man organische Verbindungen eindeutig identifizieren kann. Dieses Buch behandelt die Interpretation von Massenspektren organischer Verbindungen, und zwar auf einem für Studienanfänger und Fortgeschrittene geeigneten Niveau. Die verschiedenen organischen Verbindungen werden in einzelnen Kapiteln besprochen, wobei der Schwerpunkt auf einem verbindungsspezifischen Ansatz zur Interpretation von Massenspektren liegt. Einfach und verständlich geschrieben mit mehr als 120 repräsentativen Spektren, ist dieses Werk speziell für Studierende im 2. und 3. Studienjahr sowie für Neulinge auf diesem Gebiet gedacht. (01/98)




Mass Spectrometry for Biotechnology


Book Description

If you investigate biological systems and might use mass spectrometry in your research but need to know more about it, this book is for you. It introduces the fundamental concepts of mass spectrometry and how mass spectrometers work. It also presents recent advancements particularly interesting to bio-researchers in an easy-to-understand manner that does not require extensive background in chemistry, math, or physics. Glossary of basic terms Abundant illustrations Examples of applications Practical tips on using mass spectrometric techniques Useful for peptide, protein, oligonucleotide, and carbohydrate analysis Simplified description of mass spectrometry including: Matrix-Assisted Laser Desorption/Ionization (MALDI) Electrospray Ionization (ESI) Fast Atom/Ion Bombardment (FAB)




Mass Spectrometry


Book Description

Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.




Gas Chromatography and Mass Spectrometry: A Practical Guide


Book Description

The second edition of Gas Chromatography and Mass Spectrometry: A Practical Guide follows the highly successful first edition by F.G. Kitson, B.S. Larsen, and C.N. McEwen (1996), which was designed as an indispensible resource for GC/MS practitioners regardless of whether they are a novice or well experienced. The Fundamentals section has been extensively reworked from the original edition to give more depth of an understanding of the techniques and science involved with GC/MS. Even with this expansion, the original brevity and simple didactic style has been retained. Information on chromatographic peak deconvolution has been added along with a more in-depth understanding of the use of mass spectral databases in the identification of unknowns. Since the last edition, a number of advances in GC inlet systems and sample introduction techniques have occurred, and they are included in the new edition. Other updates include a discussion on fast GC and options for combining GC detectors with mass spectrometry. The section regarding GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types has the same number of compound types as the original edition, but the information in each section has been expanded to not only explain some of the spectra but to also explain why certain fragmentations take place. The number of Appendices has been increased from 12 to 17. The Appendix on Atomic Masses and Isotope Abundances has been expanded to provide tools to aid in determination of elemental composition from isotope peak intensity ratios. An appendix with examples on "Steps to follow in the determination of elemental compositions based on isotope peak intensities" has been added. Appendices on whether to use GC/MS or LC/MS, third-party software for use in data analysis, list of information required in reporting GC/MS data, X+1 and X+2 peak relative intensities based on the number of atoms of carbon in an ion, and list of available EI mass spectral databases have been added. Others such as the ones on derivatization, isotope peak patterns for ions with Cl and/or Br, terms used in GC and in mass spectrometry, and tips on setting up, maintaining and troubleshooting a GC/MS system have all been expanded and updated. Covers the practical instruction necessary for successful operation of GC/MS equipment Reviews the latest advances in instrumentation, ionization methods, and quantitation Includes troubleshooting techniques and a variety of additional information useful for the GC/MS practitioner A true benchtop reference A guide to a basic understanding of the components of a Gas Chromatograph-Mass Spectrometer (GC-MS) Quick References to data interpretation Ready source for information on new analyses




Practical Mass Spectrometry


Book Description

It has been estimated that more than 8090 of the world's scientists who have ever lived are still alive today. It would not be unreasonable to suggest that more than 95% of those who have ever used a mass spectrometer are not only alive but are still actively employed. Most have never had any formal training in the subject since, with a few notable exceptions, universities have only recently begun to offer courses in mass spectrometry. We have written this book for the student of modern mass spectro metry: it is for the novice who wished to know what the instruments can do and how the techniques can be applied. There are other books on the market which delve into the history of mass spectrometry and go deeply into the mathematical theory and instrumentation. There are yet more books which guide one through the art of interpreting spectra. We have deliberately avoided these topics so that the reader is confronted only with the basic principles and is allowed a taste of the applications. One of the best methods of deVeloping a useful textbook is to teach a course based upon its content. This is what we did. We met in Houston in 1976 to teach a course on "Perspectives in Mass Spectrometry" and to coordinate our writing. The authors of five of the chapters met again in St.




Comprehensive Environmental Mass Spectrometry


Book Description

"In full colour throughout, this book describes the power of mass spectrometry in resolving environmental issues, demonstrating how real-world complex problems can be solved in a simple and elegant way."--Worldcat.




The Expanding Role of Mass Spectrometry in Biotechnology


Book Description

Covers the basic concepts in mass spectrometry as well as advanced topics including protein identification/protein structural analysis, carbohydrate and oligonucleotide analysis. Topics also include pharmacokinetics, high throughput screening, and the recent development of mass spectrometry in clinical diagnosis.