Mathematics and Computer Science in Medical Imaging


Book Description

Medical imaging is an important and rapidly expanding area in medical science. Many of the methods employed are essentially digital, for example computerized tomography, and the subject has become increasingly influenced by develop ments in both mathematics and computer science. The mathematical problems have been the concern of a relatively small group of scientists, consisting mainly of applied mathematicians and theoretical physicists. Their efforts have led to workable algorithms for most imaging modalities. However, neither the fundamentals, nor the limitations and disadvantages of these algorithms are known to a sufficient degree to the physicists, engineers and physicians trying to implement these methods. It seems both timely and important to try to bridge this gap. This book summarizes the proceedings of a NATO Advanced Study Institute, on these topics, that was held in the mountains of Tuscany for two weeks in the late summer of 1986. At another (quite different) earlier meeting on medical imaging, the authors noted that each of the speakers had given, there, a long introduction in their general area, stated that they did not have time to discuss the details of the new work, but proceeded to show lots of clinical results, while excluding any mathematics associated with the area.




Introduction to the Mathematics of Medical Imaging


Book Description

At the heart of every medical imaging technology is a sophisticated mathematical model of the measurement process and an algorithm to reconstruct an image from the measured data. This book provides a firm foundation in the mathematical tools used to model the measurements and derive the reconstruction algorithms used in most of these modalities. The text uses X-ray computed tomography (X-ray CT) as a 'pedagogical machine' to illustrate important ideas and its extensive discussion of background material makes the more advanced mathematical topics accessible to people with a less formal mathematical education. This new edition contains a chapter on magnetic resonance imaging (MRI), a revised section on the relationship between the continuum and discrete Fourier transforms, an improved description of the gridding method, and new sections on both Grangreat's formula and noise analysis in MR-imaging. Mathematical concepts are illuminated with over 200 illustrations and numerous exercises.




The Mathematics of Medical Imaging


Book Description

Medical imaging is a major part of twenty-first century health care. This introduction explores the mathematical aspects of imaging in medicine to explain approximation methods in addition to computer implementation of inversion algorithms.




Fundamentals of Digital Imaging in Medicine


Book Description

In general, image processing texts are intended for students of engineering and computer science, and there is little written at all on the specific requirements of medical image processing. Students of medical radiation science (Diagnostic radiography, Nuclear medicine, Radiation therapy) usually have minimal mathematical and computer science training and find the available texts incomprehensible. A text that explains the principles of image processing in minimally-mathematical language is needed for these students. Contrary to the claims of some textbook authors, the vast majority of technologists that process images do not need to understand the mathematics involved, but would nevertheless benefit from a thorough understanding of the general process.




Introduction to Medical Image Analysis


Book Description

This easy-to-follow textbook presents an engaging introduction to the fascinating world of medical image analysis. Avoiding an overly mathematical treatment, the text focuses on intuitive explanations, illustrating the key algorithms and concepts in a way which will make sense to students from a broad range of different backgrounds. Topics and features: explains what light is, and how it can be captured by a camera and converted into an image, as well as how images can be compressed and stored; describes basic image manipulation methods for understanding and improving image quality, and a useful segmentation algorithm; reviews the basic image processing methods for segmenting or enhancing certain features in an image, with a focus on morphology methods for binary images; examines how to detect, describe, and recognize objects in an image, and how the nature of color can be used for segmenting objects; introduces a statistical method to determine what class of object the pixels in an image represent; describes how to change the geometry within an image, how to align two images so that they are as similar as possible, and how to detect lines and paths in images; provides further exercises and other supplementary material at an associated website. This concise and accessible textbook will be invaluable to undergraduate students of computer science, engineering, medicine, and any multi-disciplinary courses that combine topics on health with data science. Medical practitioners working with medical imaging devices will also appreciate this easy-to-understand explanation of the technology.




Handbook of Mathematical Methods in Imaging


Book Description

The Handbook of Mathematical Methods in Imaging provides a comprehensive treatment of the mathematical techniques used in imaging science. The material is grouped into two central themes, namely, Inverse Problems (Algorithmic Reconstruction) and Signal and Image Processing. Each section within the themes covers applications (modeling), mathematics, numerical methods (using a case example) and open questions. Written by experts in the area, the presentation is mathematically rigorous. The entries are cross-referenced for easy navigation through connected topics. Available in both print and electronic forms, the handbook is enhanced by more than 150 illustrations and an extended bibliography. It will benefit students, scientists and researchers in applied mathematics. Engineers and computer scientists working in imaging will also find this handbook useful.




Handbook of Medical Image Computing and Computer Assisted Intervention


Book Description

Handbook of Medical Image Computing and Computer Assisted Intervention presents important advanced methods and state-of-the art research in medical image computing and computer assisted intervention, providing a comprehensive reference on current technical approaches and solutions, while also offering proven algorithms for a variety of essential medical imaging applications. This book is written primarily for university researchers, graduate students and professional practitioners (assuming an elementary level of linear algebra, probability and statistics, and signal processing) working on medical image computing and computer assisted intervention. - Presents the key research challenges in medical image computing and computer-assisted intervention - Written by leading authorities of the Medical Image Computing and Computer Assisted Intervention (MICCAI) Society - Contains state-of-the-art technical approaches to key challenges - Demonstrates proven algorithms for a whole range of essential medical imaging applications - Includes source codes for use in a plug-and-play manner - Embraces future directions in the fields of medical image computing and computer-assisted intervention




Riemannian Geometric Statistics in Medical Image Analysis


Book Description

Over the past 15 years, there has been a growing need in the medical image computing community for principled methods to process nonlinear geometric data. Riemannian geometry has emerged as one of the most powerful mathematical and computational frameworks for analyzing such data. Riemannian Geometric Statistics in Medical Image Analysis is a complete reference on statistics on Riemannian manifolds and more general nonlinear spaces with applications in medical image analysis. It provides an introduction to the core methodology followed by a presentation of state-of-the-art methods. Beyond medical image computing, the methods described in this book may also apply to other domains such as signal processing, computer vision, geometric deep learning, and other domains where statistics on geometric features appear. As such, the presented core methodology takes its place in the field of geometric statistics, the statistical analysis of data being elements of nonlinear geometric spaces. The foundational material and the advanced techniques presented in the later parts of the book can be useful in domains outside medical imaging and present important applications of geometric statistics methodology Content includes: - The foundations of Riemannian geometric methods for statistics on manifolds with emphasis on concepts rather than on proofs - Applications of statistics on manifolds and shape spaces in medical image computing - Diffeomorphic deformations and their applications As the methods described apply to domains such as signal processing (radar signal processing and brain computer interaction), computer vision (object and face recognition), and other domains where statistics of geometric features appear, this book is suitable for researchers and graduate students in medical imaging, engineering and computer science. - A complete reference covering both the foundations and state-of-the-art methods - Edited and authored by leading researchers in the field - Contains theory, examples, applications, and algorithms - Gives an overview of current research challenges and future applications




Fundamentals of Medical Imaging


Book Description

Fundamentals of Medical Imaging, second edition, is an invaluable technical introduction to each imaging modality, explaining the mathematical and physical principles and giving a clear understanding of how images are obtained and interpreted. Individual chapters cover each imaging modality – radiography, CT, MRI, nuclear medicine and ultrasound – reviewing the physics of the signal and its interaction with tissue, the image formation or reconstruction process, a discussion of image quality and equipment, clinical applications and biological effects and safety issues. Subsequent chapters review image analysis and visualization for diagnosis, treatment and surgery. New to this edition: • Appendix of questions and answers • New chapter on 3D image visualization • Advanced mathematical formulae in separate text boxes • Ancillary website containing 3D animations: www.cambridge.org/suetens • Full colour illustrations throughout Engineers, clinicians, mathematicians and physicists will find this an invaluable aid in understanding the physical principles of imaging and their clinical applications.




The Mathematics of Medical Imaging


Book Description

The basic mathematics of computerized tomography, the CT scan, are aptly presented for an audience of undergraduates in mathematics and engineering. Assuming no prior background in advanced mathematical analysis, topics such as the Fourier transform, sampling, and discrete approximation algorithms are introduced from scratch and are developed within the context of medical imaging. A chapter on magnetic resonance imaging focuses on manipulation of the Bloch equation, the system of differential equations that is the foundation of this important technology. Extending the ideas of the acclaimed first edition, new material has been adeed to render an even more accessible textbook for course usage. This edition includes new discussions of the Radon transform, the Dirac delta function and its role in X-ray imaging, Kacmarz’s method and least squares approximation, spectral filtering, and more. Copious examples and exercises, new computer-based exercises, and additional graphics have been added to further delineate concepts. The use of technology has been revamped throughout with the incorporation of the open source programming environment R to illustrate examples and composition of graphics. All R code is available as extra source material on SpringerLink. From the reviews of the first edition: “This book is valuable, for it addresses with care and rigor the relevance of a variety of mathematical topics to a real-world problem. ...T his book is well written. It serves its purpose of focusing a variety of mathematical topics onto a real-world application that is in its essence mathematics.” –The Journal of Nuclear Medicine, Vol. 51 (12), December, 2010 “This new book by Timothy Feeman, truly intended to be a beginner’s guide, makes the subject accessible to undergraduates with a working knowledge of multivariable calculus and some experience with vectors and matrix methods. ...author handles the material with clarity and grace...” –The Mathematical Association of America, February, 2010