Mayo Clinic on Alzheimer's Disease


Book Description

Annotation This 13-volume set from the Mayo Clinic gives detailed information on various health conditions, for example, high blood pressure, depression, and prostate health. Each book contains a wealth of information including charts and graphs.




Neurology in Clinical Practice


Book Description

New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.




Neuropathology of Neurodegenerative Diseases


Book Description

This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.




Mild Cognitive Impairment


Book Description

What are the boundary zones between normal aging and Alzheimer's disease (AD)? Are many elderly people whom we regard as normal actually in the early stages of AD? Alzheimer's disease does not develop overnight; the early phases may last for years or even decades. Recently, clinical investigators have identified a transitional condition between normal aging and and very early Alzheimer's disease that they have called mild cognitive impairment, or MCI. This term typically refers to memory impairment beyond what one would expect in individuals of a given age whose other abilities to function in daily life are well preserved. Persons who meet the criteria for mild cognitive impairment have an increased risk of progressing to Alzheimer's disease in the near future. Though many questions about this condition and its underlying neuropathology remain open, full clinical trials are currently underway worldwide aimed at preventing the progression from MCI to Alzheimer's disease. This book addresses the spectrum of issues involved in mild cognitive impairment, and includes chapters on clinical studies, neuropsychology, neuroimaging, neuropathology, biological markers, diagnostic approaches, and treatment. It is intended for clinicians, researchers, and students interested in aging and cognition, among them neurologists, psychiatrists, geriatricians, clinical psychologists, and neuropsychologists.




Learning to Speak Alzheimer's


Book Description

A guide to more successful communication for the millions of Americans caring for someone with dementia: “Offers a fresh approach and hope.”—NPR Revolutionizing the way we perceive and live with Alzheimer’s, Joanne Koenig Coste offers a practical approach to the emotional well-being of both patients and caregivers that emphasizes relating to patients in their own reality. Her accessible and comprehensive method, which she calls habilitation, works to enhance communication between care partners and patients and has proven successful with thousands of people living with dementia. Learning to Speak Alzheimer’s also offers hundreds of practical tips, including how to: · cope with the diagnosis and adjust to the disease’s progression · help the patient talk about the illness · face the issue of driving · make meals and bath times as pleasant as possible · adjust room design for the patient’s comfort · deal with wandering, paranoia, and aggression “A fine addition to Alzheimer's and caregiving collections.”—Library Journal (starred review) “Promises to transform not only the lives of patients but those of care providers…This book is a gift.”—Sue Levkoff, coauthor of Aging Well




Live Younger Longer


Book Description

Most of us want to live a long, healthy life, but how do we do that? Drawing upon lessons from his own life, Mayo Clinic cardiologist Stephen Kopecky offers a holistic, evidence-based approach to preventing common diseases and chronic illnesses and living a longer life of pleasure and purpose. In the past century, the leading causes of death around the world have shifted from infectious diseases to long-term chronic illnesses. What’s killing us today isn’t so much flu or tuberculosis, but heart disease and cancer. In fact, more than 1.2 million Americans die from these two diseases each year. Paradoxically, these chronic diseases are a consequence of living longer than ever. But even if we’re living longer, are we living better? The overwhelming number of people now living under the burden of chronic illness indicates otherwise. After surviving two bouts of cancer, Dr. Stephen Kopecky, M.D set out to discover the behaviors people can adopt to live longer lives free of chronic illnesses and diseases. What he discovered was that the answer lies in just six habits that require small changes to your daily life, but reap big results long-term. From adopting better diet and exercise habits to managing stress and sleep, these behaviors will not only preserve your health, they can improve your quality of living and extend your life. The secret, however, lies not just in the steps themselves but in how you accomplish them. This book offers in-depth insights on: The best foods to eat and why Increasing physical activity and improving fitness Why your sleep habits matter The dangers of stress and what to do about them The true impact of alcohol and tobacco on our bodies How to make changes that will last a lifetime After 30 years of research in the field of cardiovascular disease prevention, Dr. Kopecky is sharing what he’s learned from his practice and own personal experience about staying healthy, preventing chronic illnesses, and living younger longer.




Mayo Clinic Guide to Fibromyalgia


Book Description

Called the “invisible disease,” fibromyalgia is estimated to impact more than 10 million Americans. And yet, so much is still misunderstood about this chronic disorder. Mayo Clinic Guide to Fibromyalgia is an invaluable resource for understanding fibromyalgia and its debilitating symptoms. Those living with fibromyalgia know it is an invasive disorder, one that can cause overwhelming fatigue, joint stiffness, sleep problems, migraines, digestive problems, and troubles with memory and concentration, a symptom so common it is often referred to as “fibrofog.” While it's believed that humans have suffered from fibromyalgia for hundreds, even thousands, of years, a delay in medical research means many people living with fibromyalgia are still in the dark, confused by their symptoms and what causes the painful disorder. By drawing upon decades of advanced research in studying and treating fibromyalgia, Mayo Clinic Guide to Fibromyalgia combines anecdotes from real cases with expertise from Mayo Clinic’s rheumatology and chronic pain experts to provide an all-encompassing guide for understanding one of the most common chronic illnesses affecting Americans today. This book also offers reasonable, proven strategies—like worksheets to help readers craft a personalized daily plan—for managing common fibromyalgia symptoms, while serving as a comforting guide for those who may feel alone in their journey with fibromyalgia. This book breaks down what fibromyalgia is—and isn’t—in 4 separate sections: · Section 1 introduces fibromyalgia, the history and modern discoveries of fibromyalgia research, as well as common myths and misconceptions associated with the condition · Section 2 outlines the different treatment options available to those who suffer from fibromyalgia, including prescription medications, therapies, and forms of integrative medicine · Section 3 offers helpful tips for managing—and improving—chronic pain through diet, exercise, sleep, and stress management · Finally, Section 4 explains how to find guidance and support from your family, friends, and physicians to help you live a life unhindered by fibromyalgia If you’re struggling to advance past your painful fibromyalgia symptoms, get the book Publisher’s Weekly described as “the first [book] a newly diagnosed patient should consult.”




Alzheimer's & Dementia For Dummies


Book Description

Your sensitive, authoritative guide to Alzheimer's and dementia If a loved one has recently been diagnosed with dementia or Alzheimer's disease, it's only natural to feel fraught with fear and uncertainty about what lies ahead. Fortunately, you don't have to do it alone. This friendly and authoritative guide is here to help you make smart, informed choices throughout the different scenarios you'll encounter as a person caring for someone diagnosed with dementia or Alzheimer's disease. From making sense of a diagnosis to the best ways to cope with symptoms, Alzheimer's and Dementia For Dummies is the trusted companion you can count on as you navigate your way through this difficult landscape. Affecting one's memory, thinking, and behavior, dementia and Alzheimer's disease can't be prevented, cured, or slowed—but a diagnosis doesn't mean you have to be left helpless! Inside, you'll find out how to make sense of the symptoms of dementia and Alzheimer's disease, understand the stages of the illnesses, and, most importantly, keep your loved one safe and comfortable—no matter how severe their symptoms are. Find out what to expect from Alzheimer's and dementia Discover what to keep in mind while caring for someone with Alzheimer's or dementia Uncover symptoms, causes, and risk factors of Alzheimer's and dementia Learn the critical information needed to help manage these illnesses Whether you're new to caring for a person affected by Alzheimer's or dementia or just looking for some answers and relief on your journey, this is the trusted resource you'll turn to again and again.




Sex and Gender Differences in Alzheimer's Disease


Book Description

Sex and Gender Differences in Alzheimer's Disease: The Women's Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer's disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer's disease families, in the frame of a precision medicine approach to Alzheimer's disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer's disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer's a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer's disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer's disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews: "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer's disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspired Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel




The Problem of Alzheimer's


Book Description

A definitive and compelling book on one of today's most prevalent illnesses. In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. 16 million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their seventies and eighties, the number of patients will rise to an estimated 13.8 million by 2050. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis. While it is an unambiguous account of decades of missed opportunities and our health care systems’ failures to take action, it tells the story of the biomedical breakthroughs that may allow Alzheimer’s to finally be prevented and treated by medicine and also presents an argument for how we can live with dementia: the ways patients can reclaim their autonomy and redefine their sense of self, how families can support their loved ones, and the innovative reforms we can make as a society that would give caregivers and patients better quality of life. Rich in science, history, and characters, The Problem of Alzheimer's takes us inside laboratories, patients' homes, caregivers’ support groups, progressive care communities, and Jason Karlawish's own practice at the Penn Memory Center.