Adult neurogenesis twenty years later: physiological function versus brain repair


Book Description

The discovery that mammalian brains contain neural stem cells which perform adult neurogenesis - the production and integration of new neurons into mature neural circuits - has provided a fully new vision of neural plasticity. On a theoretical basis, this achievement opened new perspectives for therapeutic approaches in restorative and regenerative neurology. Nevertheless, in spite of striking advancement concerning the molecular and cellular mechanisms which allow and regulate the neurogenic process, its exploitation in mammals for brain repair strategies remains unsolved. In non-mammalian vertebrates, adult neurogenesis also contributes to brain repair/regeneration. In mammals, neural stem cells do respond to pathological conditions in the so called "reactive neurogenesis", yet without substantial regenerative outcome. Why, even in the presence of stem cells in the brain, we lack an effective reparative outcome in terms of regenerative neurology, and which factors hamper the attainment of this goal? Essentially, what remains unanswered is the question whether (and how) physiological functions of adult neurogenesis in mammals can be exploited for brain repair purposes.




The Responsibility to Protect Twenty Years On


Book Description

This book focuses on measures pertaining to the three-pillar implementation strategy of R2P and examines how and to what extent the three pillars have been practised. Rich in its geographical scope, this edited book provides a critical analysis of R2P practice over the last two decades by focusing on representative cases from different regions. Analysing not only recent and/or underexplored cases but also widely studied cases from a fresh and alternative perspective, it sheds light on the depth and scope of the norm as well as the variety of actors involved and how they impact R2P practice. Diverging from most accounts, this edited book does not approach the cases as a ‘success’ or ‘failure’ of R2P. By studying the background to the conflicts and making assessments on a pillar-by-pillar basis, each chapter addresses the root causes, traces the process of implementation, investigates the actions of the actors involved, identifies elements of success and failure and finally questions the sustainability of the protection provided to date. Meanwhile, the conceptual chapters complement the case analyses through an overall evaluation of R2P’s first two decades and the progress achieved so far with the aim to draw lessons for future implementations of R2P.







Parliamentary Debates


Book Description







Contemporary Politics in Australia


Book Description

A diverse range of experts provide a comprehensive introduction to current theories, debates and research in Australian political science.




The Cambridge Handbook of Social Sciences in Australia


Book Description

First published in 2003, The Cambridge Handbook of Social Sciences in Australia is a high-quality reference on significant research in Australian social sciences. The book is divided into three main sections, covering the central areas of the social sciences-economics, political science and sociology. Each section examines the significant research in the field, placing it within the context of broader debates about the nature of the social sciences and the ways in which institutional changes have shaped how they are defined, taught and researched.