Author :
Publisher : Academic Press
Page : 269 pages
File Size : 49,18 MB
Release : 2011-09-16
Category : Science
ISBN : 0123876982
This latest volume in Advances in Genetics covers the genetics of Circadian rhythms. With an international group of authors this volume is the latest offering in this widely praised series.
Author : Jean-Luc Guisset
Publisher : Springer Science & Business Media
Page : 235 pages
File Size : 49,80 MB
Release : 2012-12-06
Category : Medical
ISBN : 3642799035
Rambling of an elderly biochemist Most biochemists of my generation, who were trying to discover the pathways of metabolism, simply ignored membranes; or regarded them as a nuisance. Think of the difficulties experienced in studies on cytochromoxidase which one could not separate from « insoluble material )} or again of the desperate efforts during a quarter of a century to unravel oxidative phosphorylation without paying much attention to lipidic membranes, altough the system was known to be associated with them. Hence the amazement and the general skepticism that met at first Mitchell's theory, which was giving membranes the central function they deserve in oxidative phosphorylation and photosynthesis. This, I believe, was a turning point; enzymologists thereafter became aware of the importance of the membranes. Neurophysiologists, of course, had long been interested in the outer cell membrane with its electrical properties and the ion potentials. Histologists and electronmicroscopists also, who observed inside the cell.organelles of which membranes are essential components: nucleus, nucleoli, mitchondria, lysosomes,Golgi apparatus, endoplasmic reticulum, chloroplasts. For them at least, a cell did not look like a mere bag full of enzymes and small molecules; they knew, they could see that it is a highly structured system divided into many compartments by membranous formations.
Author : Urs Albrecht
Publisher : Springer Science & Business Media
Page : 306 pages
File Size : 26,49 MB
Release : 2010-01-23
Category : Science
ISBN : 1441912622
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
Author : Vinod Kumar
Publisher : Springer
Page : 663 pages
File Size : 15,2 MB
Release : 2017-02-15
Category : Science
ISBN : 8132236882
This book is a concise, comprehensive and up-to-date account of fundamental concepts and potential applications of biological timekeeping mechanisms in animals and humans. It also discusses significant aspects of the organization and importance of timekeeping mechanisms in both groups. Divided into seven sections, it addresses important aspects including fundamental concepts; animal and human clocks; clock interactions; clocks and metabolism and immune functions; pineal, melatonin and timekeeping; and clocks, photoperiodism and seasonal behaviours. The book also focuses on biological clock applications in a 24x7 human society, particularly in connection with life-style associated disorders like obesity and diabetes. It is a valuable resource for advanced undergraduates, researchers and professionals engaged in the study of the science of biological timekeeping.
Author : Paolo Sassone-Corsi
Publisher : Springer
Page : 141 pages
File Size : 28,57 MB
Release : 2016-04-04
Category : Medical
ISBN : 3319270699
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
Author : Daniel B. Forger
Publisher : MIT Press
Page : 369 pages
File Size : 31,54 MB
Release : 2024-08-06
Category : Science
ISBN : 0262552817
An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.
Author : Jon W. Jacklet
Publisher :
Page : 584 pages
File Size : 22,60 MB
Release : 1989
Category : Medical
ISBN :
Providing refined explanations for many of the known oscillators, this reference describes the membrane and cellular mechanisms of biological tissues that are repetitively active, including heart tissue, most neurons, and secretory cells. It examines three major types of oscillator: network oscillators involving synaptic interaction among neurons, cytoplasmic component oscillators, and cell membrane oscillators and their associated ion channels. For neurobiologists, anatomists, cell biologists, and zoologists. Annotation(c) 2003 Book News, Inc., Portland, OR (booknews.com)
Author : Josh Dubnau
Publisher : Cambridge University Press
Page : 309 pages
File Size : 22,67 MB
Release : 2014-06-26
Category : Medical
ISBN : 1107009030
A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.
Author : Stefano Mancuso
Publisher : Springer
Page : 405 pages
File Size : 23,80 MB
Release : 2015-06-29
Category : Science
ISBN : 331920517X
This second edition of a well-received book focuses on rhythmic behaviour in plants, which regulates all developmental and adaptive responses and can thus be regarded as quintessential to life itself. The chapters provide a timely update on recent advances in this field and comprehensively summarize the current state of knowledge concerning the molecular and physiological mechanisms behind circadian and ultradian oscillations in plants, their physiological implications for growth and development and adaptive responses to a dynamic environment. Written by a diverse group of leading researchers, the book will spark the interest of readers from many branches of science: from physicists and chemists wishing to learn about the multi-faceted rhythms in plants, to biologists and ecologists involved in the state-of-the-art modelling of complex rhythmic phenomena.
Author : I. Nir
Publisher :
Page : 420 pages
File Size : 18,38 MB
Release : 2015-01-07
Category :
ISBN : 9783709144282
