Metabolic Pathways: Amino acids and tetrapyrroles


Book Description

Surveys the existing knowledge of the chemical steps in the metabolism of the constituents of major importance in living organisms -- Preface volume 1.




Biochemical Pathways


Book Description

The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function. Biochemical Pathways examines the biochemistry of bacteria, plants, and animals. It offers a quick overview of the metabolic sequences in biochemical pathways, the chemistry and enzymology of conversions, the regulation of turnover, the expression of genes, the immunological interactions, and the metabolic background of health disorders. A standard set of conventions is used in all illustrations, enabling readers to easily gather information and compare the key elements of different biochemical pathways. For both quick and in-depth understanding, the book uses a combination of: Illustrations integrating many different features of the reactions and their interrelationships Tables listing the important system components and their function Text supplementing and expanding on the illustrated facts In the second edition, the volume has been expanded by 50 percent. Text and figures have undergone a thorough revision and update, reflecting the tremendous progress in biochemical knowledge in recent years. A guide to the relevant biochemical databases facilitates access to the extensive documentation of scientific knowledge. Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems. From the reviews: “… highly recommended for every scientist and student working in biochemistry.” –Umwelt & Gesundheit 4/2012 (review in German language)




Prokaryotic Metabolism and Physiology


Book Description

Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.







The Organic Chemistry of Biological Pathways


Book Description

Intended for advanced undergraduates and graduate students in all areas of biochemistry, The Organic Chemistry of Biological Pathways provides an accurate treatment of the major biochemical pathways from the perspective of mechanistic organic chemistry.




Introduction to Modern Biochemistry 4e


Book Description

Introduction to Modern Biochemistry, Fourth Edition provides an understanding of the chemical background of biological phenomena. This book discusses the concepts of generation and utilization of free energy. Organized into 23 chapters, this edition starts with an overview of the important role of amides in biochemistry. This text then explores the chemical structure of proteins and describes the methods of determining the amino acids sequence of proteins. Other chapters consider the role of genes in protein and enzyme synthesis. This book discusses as well the significance of the submicroscopic structure of the cell in biochemical reactions. The reader is also introduced to the chemistry of the carbohydrates. The final chapter deals with biochemical functions of various organs, including the digestive tract, liver, kidney, nervous system, muscles, and connective tissues. This book is a valuable resource for biologists, biochemists, scientists, researchers, and readers who are interested in the field of biochemistry.




Biological Inorganic Chemistry


Book Description

The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on.Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject.Many colour illustrations. Enables easier visualization of molecular mechanismsWritten by a single author. Ensures homgeneity of style and effective cross referencing between chapters




Introduction to Modern Biochemistry 3e


Book Description

Introduction to Modern Biochemistry, Fourth Edition provides a better understanding of the chemical background of biological phenomena. The book presents an introduction and a survey of the facts and concepts of biochemistry. The text is intended to be an instructional material. Topics of general importance, such as the generation and utilization of free energy, the role of genes in protein and enzyme synthesis, and the importance of the submicroscopic structure of the cell in biochemical reactions, are emphasized. No distinction between descriptive biochemistry and dynamic biochemistry are made, for the sake of simplicity and better comprehension of concepts presented in the book. Students, biochemists, biologists, pharmacists, and medical practitioners will find this book as a good reference.




Tetrapyrroles


Book Description

Excluding the biological polymers proteins, lipids and nucleic acids, modified tetrapyrroles are the biological molecules that have had the greatest impact on the evolution of life over the past 4 billion years. They are involved in a wide variety of fundamental processes that underpin central primary metabolism in all kingdoms of life, from photosynthesis to methanogenesis. Moreover, they bring colour into the world and it is for this reason that these compounds have been appropriately dubbed the ‘pigments of life’. To understand how and why these molecules have been so universally integrated into the life processes one has to appreciate the chemical properties of the tetrapyrrole scaffold and, where appropriate, the chemical characteristics of the centrally chelated metal ion. This book addresses why these molecules are employed in Nature, how they are made and what happens to them after they have finished their usefulness.




The Porphyrin Handbook


Book Description

The Porphyrin Handbook, Volume 12: The Iron and Cobalt Pigments: Biosynthesis, Structure, and Degradation provides information pertinent to every aspect of the chemistry, synthesis, spectroscopy, and structure of phthalocyanines. This book presents the biochemical and clinical aspects of genetically transmitted or drug-induced diseases associated with errors in heme metabolism. Organized into eight chapters, this volume begins with an overview of the comparison of regulatory principles in animal and plant tetrapyrrole biosynthesis. This text then examines the biology and medical implications of porphyrin systems. Other chapters consider the transformation of hemes into bile pigments, the organic synthesis of bilins, and the pathways of degradation of chlorophyll in senescent plants. This book discusses as well the biosynthesis of porphyrins, vitamin B12, and chlorophylls. The final chapter deals with genome sequencing projects that provide sources of genes encoding the enzymes needed for the synthesis of the intermediates. This book is a valuable resource for research scientists, engineers, and clinicians.