Methionine Hydroxy Analog Production Process - Cost Analysis - Methionine E51A


Book Description

This report presents a cost analysis of Methionine Hydroxy Analog production from methional and hydrogen cyanide (HCN). The process examined is similar to a process developed by Novus. This process first involves the reaction between methional and hydrogen cyanide, producing the hydroxy methylthiobutyronitrile (HMBN) intermediate. The HMBN is further hydrolyzed to produce Methionine Hydroxy Analog. This report was developed based essentially on the following reference(s): (1) US Patent 6458997B2, issued to Novus International, Inc. in 2002 (2) US Patent 4524077, issued to Monsanto Company in 1985 (assigned to Novus International, Inc. in 1991) Keywords: MHA, HMTBA, HMBN, 3-Methylmercapto Propionaldehyde, MMP, Methional, Essential Amino Acid




Methionine Hydroxy Analog Production Process - Cost Analysis - Methionine E61A


Book Description

This report presents a cost analysis of Methionine Hydroxy Analog production from acrolein, methyl mercaptan, and hydrogen cyanide (HCN) The process examined is similar to a process developed by Novus. In this process methional is produced from acrolein and methyl mercaptan. The methional reacts with hydrogen cyanide to produce hydroxy methylthiobutyronitrile (HMBN) intermediate, which is hydrolyzed to Methionine Hydroxy Analog. The product is recovered from the reaction medium via a solvent extraction. This report was developed based essentially on the following reference(s): (1) US Patent 6458997B2, issued to Novus International, Inc. in 2002 (2) US Patent 6320076, issued to Novus International, Inc. in 2001 Keywords: MHA, HMTBA, HMBN, 3-Methylmercapto Propionaldehyde, MMP, Methional, Propenal, Methanethiol, Essential Amino Acid




DL-Methionine from Propylene, Methyl Mercaptan and HCN - Cost Analysis - Methionine E71A


Book Description

This report presents a cost analysis of Methionine production from propylene, methyl mercaptan and hydrogen cyanide (HCN) In the process examined, propylene starting material is oxidized to acrolein, which is then reacted with methyl mercaptan to generate methional (a.k.a. MMP). Finally, methional is reacted with hydrogen cyanide to form methionine. This report was developed based essentially on the following reference(s): (1) US Patent 20130231501, issued to Evonik in 2013 (2) US Patent 8877981, issued to Evonik in 2014 Keywords: Methanethiol, MeSH, Propenal, Oxidation, Propene, DLM, 3-Methylmercapto Propionaldehyde, MMP, Methional, Essential Amino Acid, Degussa




DL-Methionine from Methional and Hydrogen Cyanide - Cost Analysis - Methionine E11A


Book Description

This report presents a cost analysis of DL-Methionine production from methional and hydrogen cyanide (HCN) The process examined is a typical carbonate process. This process is a multi-step process including: hydantoin intermediate production; reaction of hydantoin with potassium carbonate to produce potassium methioninate; and methioninate conversion to DL-Methionine. This report was developed based essentially on the following reference(s): US Patent 20130231501, issued to Evonik in 2013 Keywords: DLM, 3-Methylmercapto Propionaldehyde, MMP, Methional, Essential Amino Acid, Degussa




Bio-Methionine Production from Glucose - Cost Analysis - Methionine E31A


Book Description

This report presents a cost analysis of L-Methionine production from glucose syrup using a direct fermentation process The process examined is similar to the one developed by Metabolic Explorer. In this process, a 70 wt% glucose-water syrup is used as raw material. Besides L-Methionine Powder, an aqueous Methionine solution is also produced in the process. This report was developed based essentially on the following reference(s): (1) US Patent 20150045434, issued to Roquette Freres in 2015 (assigned to Metabolic Explorer in 2015) (2) US Patent 20140134680, issued to Metabolic Explorer in 2014 Keywords: Dextrose, MetEx, Ajinomoto, CJ Bio, Arkema, Aerobic Fermentation, Essential Amino Acid, Roquette Freres




DL-Methionine from Acrolein, Methyl Mercaptan and HCN - Cost Analysis - Methionine E41A


Book Description

This report presents a cost analysis of DL-Methionine production from acrolein, methyl mercaptan, and hydrogen cyanide (HCN). The process examined is a typical carbonate process. In this process, refined acrolein and methyl mercaptan are reacted to form MMP (also called methional), which is further reacted with hydrogen cyanide to generate DL-Methionine. This multi-step process includes: methional production; hydantoin intermediate production (from methional and hydrogen cyanide); reaction of hydantoin with potassium carbonate to produce potassium methioninate; and methioninate conversion to DL-Methionine. This report was developed based essentially on the following reference(s): (1) US Patent 20130231501, issued to Evonik in 2013 (2) US Patent 8759592, issued to Evonik in 2014 Keywords: DLM, 3-Methylmercapto Propionaldehyde, MMP, Methional, Propenal, Methanethiol, Essential Amino Acid, Degussa




Bio-Methionine Production from Raw Sugar - Cost Analysis - Methionine E21B


Book Description

This report presents a cost analysis of L-Methionine production from raw sugar using a direct fermentation process The process examined is similar to the one developed by Metabolic Explorer. In this process, raw sugar (sucrose) is diluted and sucrose is hydrolyzed into glucose and fructose (invert sugars). The invert sugars are then fermented to produce L-Methionine. Besides L-Methionine powder, an aqueous Methionine solution is also produced in the process. This report was developed based essentially on the following reference(s): (1) US Patent 20150045434, issued to Roquette Freres in 2015 (assigned to Metabolic Explorer in 2015) (2) US Patent 20140134680, issued to Metabolic Explorer in 2014 Keywords: Dextrose, MetEx, Ajinomoto, CJ Bio, Arkema, Aerobic Fermentation, Essential Amino Acid, Roquette Freres




A Structural Perspective on Respiratory Complex I


Book Description

The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.