Microbial Forensics


Book Description

Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science. Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes. A collection of microbiology, virology, toxicology and mycology as it relates to forensics, in one reference New and expanded content to include statistical analysis of forensic data and legal admissibility and the standards of evidence, to name a few Includes research information and application of that research to crime scene analysis, which will allow practitioners to understand and apply the knowledge to their practice with ease




Forensic Microbiology


Book Description

Forensic Microbiology focuses on newly emerging areas of microbiology relevant to medicolegal and criminal investigations: postmortem changes, establishing cause of death, estimating postmortem interval, and trace evidence analysis. Recent developments in sequencing technology allow researchers, and potentially practitioners, to examine microbial communities at unprecedented resolution and in multidisciplinary contexts. This detailed study of microbes facilitates the development of new forensic tools that use the structure and function of microbial communities as physical evidence. Chapters cover: Experiment design Data analysis Sample preservation The influence of microbes on results from autopsy, toxicology, and histology Decomposition ecology Trace evidence This diverse, rapidly evolving field of study has the potential to provide high quality microbial evidence which can be replicated across laboratories, providing spatial and temporal evidence which could be crucial in a broad range of investigative contexts. This book is intended as a resource for students, microbiologists, investigators, pathologists, and other forensic science professionals.




Science Needs for Microbial Forensics


Book Description

For these reasons, building awareness of and capacity in microbial forensics can assist in our understanding of what may have occurred during a biothreat event, and international collaborations that engage the broader scientific and policy-making communities are likely to strengthen our microbial forensics capabilities. One goal would be to create a shared technical understanding of the possibilities--and limitations--of the scientific bases for microbial forensics analysis. Science Needs for Microbial Forensics: Developing Initial International Research Priorities, based partly on a workshop held in Zabgreb, Croatia in 2013, identifies scientific needs that must be addressed to improve the capabilities of microbial forensics to investigate infectious disease outbreaks and provide evidence of sufficient quality to support legal proceedings and the development of government policies.




Forensic Ecogenomics


Book Description

Forensic Ecogenomics: The Application of Microbial Ecology Analyses in Forensic Contexts provides intelligence on important topics, including environmental sample provenance, how to indicate the body decomposition timeline to support postmortem interval (PMI) and postmortem submersion interval (PMSI) estimates, and how to enhance identification of clandestine and transit grave locations. A diverse group of international experts have come together to present a clear perspective of forensic ecogenomics that encapsulates cutting-edge, topical and relevant cross-disciplinary approaches vital to the field. Considers the effects of decomposition on bacterial, fungal and mesofaunal populations in pristine ecosystems Examines the role of the microbiome, necrobiome and thanatomicrobiome in postmortem interval estimations Focuses on the application of different analytical techniques across forensics to enhance/expand the crime scene investigation toolkit Written by a wide range of international experts in their respective fields




Microbial Diversity, Interventions and Scope


Book Description

This book focuses on the application of microbes in all fields of biology. There is an urgent need to understand and explore new microbes, their biological activities, genetic makeup and further opportunities for utilizing them. The book is divided into sections, highlighting the application of microbes in agriculture, nanotechnology, genetic engineering, bioremediation, industry, medicine and forensic sciences, and describing potential future advances in these fields. It also explores the potential role of microbes in space and how they might support life on a different planet.




Criminal and Environmental Soil Forensics


Book Description

Soils have important roles to play in criminal and environmental forensic science. Since the initial concept of using soil in forensic investigations was mooted by Conan Doyle in his Sherlock Holmes stories prior to real-world applications, this branch of forensic science has become increasingly sophisticated and broad. New techniques in chemical, physical, biological, ecological and spatial analysis, coupled with informatics, are being applied to reducing areas of search by investigators, site identification, site comparison and measurement for the eventual use as evidence in court. Soils can provide intelligence, in assisting the determination of the provenance of samples from artifacts, victims or suspects, enabling their linkage to locations or other evidence. They also modulate change in surface or buried cadavers and hence affect the ability to estimate post-mortem or post-burial intervals, and locate clandestine graves. This interdisciplinary volume explores the conceptual and practical interplay of soil and geoforensics across the scientific, investigative and legal fields. Supported by reviews, case-studies from across the world, and reports of original research, it demonstrates the increasing convergence of a wide range of knowledge. It covers conceptual issues, evidence (from recovery to use in court), geoforensics, taphonomy, as well as leading-edge technologies. The application of the resultant soil forensics toolbox is leading to significant advances in improving crime detection, and environmental and national security.




Estimation of the Time Since Death


Book Description

Estimation of the Time Since Death remains the foremost authoritative book on scientifically calculating the estimated time of death postmortem. Building on the success of previous editions which covered the early postmortem period, this new edition also covers the later postmortem period including putrefactive changes, entomology, and postmortem r




Tactical Sciences for Biosecurity in Animal and Plant Systems


Book Description

Agriculture is often under the threat of invasive species of animal pests and pathogens that do harm to crops. It is essential to have the best methods and tools available to prevent this harm. Biosecurity is a mixture of institutions, policies, and science applications that attempts to prevent the spread of unhealthy pests. Tactical Sciences for Biosecurity in Animal and Plant Systems focuses on the tactical sciences needed to succeed in the biosecurity objectives of preventing plant and animal pathogens from entering or leaving the United States. This book explores a divergence of tactics between plant and animal exotic disease response. Covering topics such as animal pests and pathogens, tactical management, and early detection, this book is an essential resource for researchers, academicians, university faculty, government biosecurity practitioners, customs officers, clinical scientists, and students.




The New Science of Metagenomics


Book Description

Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.




Applications in Forensic Proteomics


Book Description

Introduction to forensic proteomics -- A proteomics tutorial -- Proteomic sample preparation techniques : toward forensic proteomic applications -- NextGen serology : leveraging mass spectrometry for protein-based human body fluid identification -- Informatics approaches to forensic body fluid identification by proteomic mass spectrometry -- Fingermarks as a new proteomic specimen : state of the art and perspective of in situ proteomics -- Human identification using genetically variant peptides in biological forensic evidence -- Proteomics in the analysis of forensic, archaeological, and paleontological bone -- Proteomics for microbial forensics -- ISO 17025 accreditation of method-based mass spectrometry for bioforensic analyses -- Unambiguous identification of ricin and abrin with advanced mass spectrometric assays -- Challenges in the development of reference materials for protein toxins -- The statistical defensibility of forensic proteomics.