Author : Antonio Tito Fojo
Publisher : Springer Science & Business Media
Page : 629 pages
File Size : 50,96 MB
Release : 2009-01-14
Category : Medical
ISBN : 1597453366
This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.
Author : John J. Correia
Publisher : Academic Press
Page : 472 pages
File Size : 33,27 MB
Release : 2013-08-20
Category : Science
ISBN : 0124078885
There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This Second Edition brings together current research and protocols in the field of microtubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. Chapters reflect experimental procedures and new developments in the field of microtubule in vitro research Combines classical approaches and modern technologies Presents easy-to-use protocols and thorough background information, compiled by leaders in the field
Author : Bruce Alberts
Publisher :
Page : 0 pages
File Size : 45,20 MB
Release : 2002
Category : Cytology
ISBN : 9780815332183
Author : Jens Lüders
Publisher : Springer
Page : 193 pages
File Size : 11,3 MB
Release : 2016-04-08
Category : Science
ISBN : 3709119030
This book provides an overview on the organization and function of the microtubule cytoskeleton, which is essential to many cellular processes and profoundly linked to a range of human diseases. Covering basic concepts as well as molecular details, the book discusses how microtubules are nucleated and organized into ordered arrays, at different cell cycle stages and in distinct cell types. In addition, the book highlights how defects in the microtubule cytoskeleton are linked to diseases such as neurodevelopmental disorders. The book is intended for students, graduates and more senior researchers in cell and developmental biology as well as for medical doctors.
Author : Toshiyuki Nagata
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 39,38 MB
Release : 2013-03-09
Category : Technology & Engineering
ISBN : 3662105721
The first compilation of a wealth of knowledge on tobacco BY-2 cells, often cited as the HeLa cell line of higher plants. Basic issues of cell cycle progression, cytokinesis, cell organization and factors that are involved in these processes are covered in detail. Since the tobacco cell line is used as a tool for research in molecular and cellular biology, several chapters on such studies are also included. Further, changes of primary and secondary metabolites during culture and factors that affect these processes are treated. Last but not least, the so far unpublished historical background of the BY-2 cell line is described. This volume is a must for any scientist working in the field of plant biology.
Author : Pierre Dustin
Publisher : Springer Science & Business Media
Page : 499 pages
File Size : 44,36 MB
Release : 2012-12-06
Category : Science
ISBN : 364269652X
The decision, in 1975, to write alone a monograph on micro tubules was not without risks. While I was familiar from its start in Brussels in 1934 with the work on col chicine and other mitotic poisons, the literature on microtubules was, 8 years ago, already increasing at an impressive rate. However, this monograph, which, contrary to other works on microtubules, tried to cover the whole field of research, from the fundamentals of the tubulin molecule and the possible role of these organelles in some aspects of human pathology, to some medical applications of microtubule poisons, has been accepted as a useful tool for workers in these fields. Since 1976, (date of the last references mentioned in the monograph) until the middle of 1983, papers on microtubule research have literally been pouring in, at the rate of several hundred a year. This may justify a second edition, although the considerable difficulties in keeping the size of the book within the same limits while not forgetting to mention some important work, could not be overlooked. The need for an entirely revised and rewritten edition prompted this new venture and was possible with the help of the considerable amount of reprints kindly sent to me day after day over the years. This work would have been unthinkable if the author had not maintained the same enthusiasm for microtubule research, which has been disclosing new facts every day.
Author : Eric Wong
Publisher : Axolotl Academic Publishing
Page : 283 pages
File Size : 23,69 MB
Release : 2009
Category : Biology
ISBN : 0985226110
"Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.
Author : Bo Liu
Publisher : Springer Science & Business Media
Page : 333 pages
File Size : 45,9 MB
Release : 2010-11-23
Category : Science
ISBN : 1441909877
Plant cells house highly dynamic cytoskeletal networks of microtubules and actin microfilaments. They constantly undergo remodeling to fulfill their roles in supporting cell division, enlargement, and differentiation. Following early studies on structural aspects of the networks, recent breakthroughs have connected them with more and more intracellular events essential for plant growth and development. Advanced technologies in cell biology (live-cell imaging in particular), molecular genetics, genomics, and proteomics have revolutionized this field of study. Stories summarized in this book may inspire enthusiastic scientists to pursue new directions toward understanding functions of the plant cytoskeleton. The Plant Cytoskeleton is divided into three sections: 1) Molecular Basis of the Plant Cytoskeleton; 2) Cytoskeletal Reorganization in Plant Cell Division; and 3) The Cytoskeleton in Plant Growth and Development. This book is aimed at serving as a resource for anyone who wishes to learn about the plant cytoskeleton beyond ordinary textbooks.
Author : J. Reinert
Publisher : Springer Science & Business Media
Page : 354 pages
File Size : 48,21 MB
Release : 2013-11-11
Category : Science
ISBN : 3540363963
The first volume of the series, on "The Stability of the Differentiated State" received many favorable reviews from the scientific community. Many readers seem to agree with us that publication of topical volumes is a worthwhile alternative to periodic compilations of rather unrelated, though up-to-date reviews. Production of topical volumes is however, plagued with one great difficulty, that of "author synchronization". This difficulty explains the lag between volumes 1 and 2 of the series. Nevertheless we hope that the present volume will be appreciated as a valuable source of information on its central topic: How do cell organelles originate, and what mechanisms assure their continuity? Tübingen, Berlin, Zürich, \V. BEERMANN, J. REINERT, H. URSPRUNG, Heidelberg H. -W. HA GENS Contents Assembly, Continuity, and Exchanges in Certain Cytoplasmic Membrane Systems by W. GORDON WHALEY, MARIANNE DAUWALDER, aüd ]OYCE E. KEPHART 1 I. The Nature of the Membrane. . . . . . H. The Assembly of Membranes . . . . . . 5 III. The Growth and Transfer of Membranes. 6 A. The Nuclear Envelopc . . . 6 B. The Endoplasmic Reticulum 13 C. The Golgi Apparatus . 17 D. The Plasma Membrane 28 E. Vacuoles and Vesicles 31 IV. Concluding Remarks 37 References . . . . . 38 Origin and Continuity of Mitochondria by ROBERT BAXTER 1. Introduction . . . . . . . . . . . . . 46 H. Mitochondrial Biogenesis : thc Machincry 46 III. Limitations of Mitochondrial Autonomy 50 IV. The Replication of Mitochondria 53 V. Discussion and Conclusion 58 Referenccs . . . . . . . . . 59 Origin and Continuity of Plastids by \VILFRIED STUBBE 1. Introduction . . . . . . . . . . . . . 65 II. Arguments for the Continuity of Plastids .
Author : Ron Milo
Publisher : Garland Science
Page : 400 pages
File Size : 16,6 MB
Release : 2015-12-07
Category : Science
ISBN : 1317230698
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
