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MiRNomics

Author : Malik Yousef

Publisher :

Page : 333 pages

File Size : 23,17 MB

Release : 2014

Category : RNA

ISBN : 9781627037488

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Book Description

In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective. These include methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, miRNomics: MicroRNA Biology and Computational Analysis seeks to aid scientists in the further study into miRNA research and statistics.





Applied Bioinformatics

Author : Paul Maria Selzer

Publisher : Springer Science & Business Media

Page : 297 pages

File Size : 19,25 MB

Release : 2008-01-18

Category : Science

ISBN : 3540728007

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Book Description

At last, here is a baseline book for anyone who is confused by cryptic computer programs, algorithms and formulae, but wants to learn about applied bioinformatics. Now, anyone who can operate a PC, standard software and the internet can also learn to understand the biological basis of bioinformatics, of the existence as well as the source and availability of bioinformatics software, and how to apply these tools and interpret results with confidence. This process is aided by chapters that introduce important aspects of bioinformatics, detailed bioinformatics exercises (including solutions), and to cap it all, a glossary of definitions and terminology relating to bioinformatics.



PlantOmics: The Omics of Plant Science

Author : Debmalya Barh

Publisher : Springer

Page : 839 pages

File Size : 45,63 MB

Release : 2015-03-18

Category : Science

ISBN : 8132221729

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Book Description

PlantOmics: The Omics of Plant Science provides a comprehensive account of the latest trends and developments of omics technologies or approaches and their applications in plant science. Thirty chapters written by 90 experts from 15 countries are included in this state-of-the-art book. Each chapter describes one topic/omics such as: omics in model plants, spectroscopy for plants, next generation sequencing, functional genomics, cyto-metagenomics, epigenomics, miRNAomics, proteomics, metabolomics, glycomics, lipidomics, secretomics, phenomics, cytomics, physiomics, signalomics, thiolomics, organelle omics, micro morphomics, microbiomics, cryobionomics, nanotechnology, pharmacogenomics, and computational systems biology for plants. It provides up to date information, technologies, and their applications that can be adopted and applied easily for deeper understanding plant biology and therefore will be helpful in developing the strategy for generating cost-effective superior plants for various purposes. In the last chapter, the editors have proposed several new areas in plant omics that may be explored in order to develop an integrated meta-omics strategy to ensure the world and earth’s health and related issues. This book will be a valuable resource to students and researchers in the field of cutting-edge plant omics.



Cancer and Noncoding RNAs

Author : Jayprokas Chakrabarti

Publisher : Academic Press

Page : 578 pages

File Size : 17,17 MB

Release : 2017-10-13

Category : Medical

ISBN : 0128134372

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Book Description

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches. This book will help researchers in genomic medicine and cancer biology better understand the role of noncoding RNAs in epigenetics, aiding in the development of useful biomarkers for diagnosis, prognosis and new RNA-based disease therapies. - Provides a comprehensive analysis of noncoding RNAs implicated in epigenetic regulation of gene expression and chromatin dynamics - Educates researchers and graduate students by highlighting, in addition to miRNAs, a range of noncoding RNAs newly associated with carcinogenesis - Applies current knowledge of noncoding RNAs and epigenomics towards developing cancer and RNA-based disease therapies - Features contributions by leading experts in the field



AI and Machine Learning Paradigms for Health Monitoring System

Author : Hasmat Malik

Publisher : Springer Nature

Page : 513 pages

File Size : 25,9 MB

Release : 2021-02-14

Category : Technology & Engineering

ISBN : 9813344121

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Book Description

This book embodies principles and applications of advanced soft computing approaches in engineering, healthcare and allied domains directed toward the researchers aspiring to learn and apply intelligent data analytics techniques. The first part covers AI, machine learning and data analytics tools and techniques and their applications to the class of several hospital and health real-life problems. In the later part, the applications of AI, ML and data analytics shall be covered over the wide variety of applications in hospital, health, engineering and/or applied sciences such as the clinical services, medical image analysis, management support, quality analysis, bioinformatics, device analysis and operations. The book presents knowledge of experts in the form of chapters with the objective to introduce the theme of intelligent data analytics and discusses associated theoretical applications. At last, it presents simulation codes for the problems included in the book for better understanding for beginners.



Molecular Biology and Biotechnology

Author : Ralph Rapley

Publisher : Royal Society of Chemistry

Page : 574 pages

File Size : 25,18 MB

Release : 2015-11-09

Category : Science

ISBN : 1782625518

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Book Description

One of the exciting aspects of being involved in the field of molecular biology is the ever-accelerating rate of progress, both in the development of new methodologies and the practical applications of these methodologies. This popular textbook has been completely revised and updated to provide a comprehensive overview and to reflect key developments in this rapidly expanding area. Chapters on the impact of molecular biology in the development of biotechnology have been fully updated and include the applications of molecular biology in the areas of diagnostics, biosensors and biomarkers, therapeutics, agricultural biotechnology and vaccines. The first six chapters deal with the technology used in current molecular biology and biotechnology. These primarily deal with core nucleic acid techniques, genomics, proteomics and recombinant protein production. Further chapters address major advances in the applications of molecular biotechnology. By presenting information in an easily assimilated form, this book makes an ideal undergraduate text. Molecular Biology and Biotechnology 6th Edition will be of particular interest to students of biology and chemistry, as well as to postgraduates and other scientific workers who need a sound introduction to this ever rapidly advancing and expanding area.



Systems Biology Application in Synthetic Biology

Author : Shailza Singh

Publisher : Springer

Page : 166 pages

File Size : 27,91 MB

Release : 2016-09-08

Category : Science

ISBN : 813222809X

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Book Description

This book introduces students to methods that will help them understand behaviour in terms of cellular components and their interactions in non-intuitive ways, which calls for an interdisciplinary approach combining mathematical, chemical, computational and biological strategies. Tibor Ganti was one of the early pioneers who proposed a theoretical framework to understand living principles in terms of chemical transformation cycles and their coupling. The twenty-first century then brought with it a novel ‘systems’ paradigm, which shone new light on all previous work and was accompanied by numerous implications for the way we conceive of chemical and biological complexity today. This book seeks to equip students to take advantage of any field that investigates living systems. Based on a conceptualisation of science-oriented branches, engineering-oriented branches and biology as astoundingly complex fields, those structures laden with biochemical detail encompass a deeper theory unifying our knowledge of designed systems. Readers will be pleasantly surprised at how lucidly the topics are presented. The book offers an indispensable resource for students and professionals working in systems and synthetic biology or any of the various related fields of research.



Brachypodium Genomics

Author : Gaurav Sablok

Publisher : Humana Press

Page : 328 pages

File Size : 34,41 MB

Release : 2019-11-03

Category :

ISBN : 9781493984398

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Book Description

This volume presents protocols for Brachypodium genomics in numerous areas ranging from marker development, trait evolution, functional genomics, metabolomics, transcriptomics, genomics, and tilling. This book also explores techniques to study the widening genetic base of Brachypodium that will help researchers better understand the model plant using NGS technologies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Brachypodium Genomics: Methods and Protocols is a valuable resource for bench-oriented molecular biologists and computational biologists working towards further evolving this field.



Plant Epigenetics

Author : Nikolaus Rajewsky

Publisher : Springer

Page : 540 pages

File Size : 23,93 MB

Release : 2017-04-27

Category : Science

ISBN : 3319555200

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Book Description

This book presents, in 26 chapters, the status quo in epigenomic profiling. It discusses how functional information can be indirectly inferred and describes the new approaches that promise functional answers, collectively referred to as epigenome editing. It highlights the latest important advances in our understanding of the functions of plant epigenomics and new technologies for the study of epigenomic marks and mechanisms in plants. Topics include the deposition or removal of chromatin modifications and histone variants, the role of epigenetics in development and response to environmental signals, natural variation and ecology, as well as applications for epigenetics in crop improvement. Discussing areas ranging from the complex regulation of stress and heterosis to the precise mechanisms of DNA and histone modifications, it presents breakthroughs in our understanding of complex phenotypic phenomena.